Risk factors predicting subsequent falls and osteoporotic fractures at 4 years after distal radius fracture—a prospective cohort study

2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Neha Dewan ◽  
Joy C. MacDermid ◽  
Ruby Grewal ◽  
Karen Beattie
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Distal Radius Fracture ◽  
Distal Radius ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Osteoporotic Fractures ◽  
Radius Fracture

Patient-centered care and distal radius fracture outcomes: A prospective cohort study analysis

2014 ◽  
Vol 27 (3) ◽  
pp. 177-184 ◽  
Author(s):  
Marissa K. Constand ◽  
Joy C. MacDermid ◽  
Mary Law ◽  
Vanina Dal Bello-Haas
Keyword(s):  
Cohort Study ◽  
Distal Radius Fracture ◽  
Distal Radius ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Patient Centered Care ◽  
Radius Fracture ◽  
Study Analysis ◽  
Patient Centered ◽  
Centered Care

scholarly journals Radial BMD and serum CTX-I can predict the progression of carotid plaque in rheumatoid arthritis: a 3-year prospective cohort study

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Seungwoo Han ◽  
Na-Ri Kim ◽  
Jong-Wan Kang ◽  
Jung-Su Eun ◽  
Young-Mo Kang
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Cohort Study ◽  
Distal Radius ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Carotid Plaque ◽  
Plaque Progression ◽  
Bone Parameters ◽  
Atherosclerotic Burden

Abstract Objective Patients with rheumatoid arthritis (RA) are almost twice as likely to develop cardiovascular disease (CVD) as those without. However, traditional CVD risks have been shown to underperform in RA patients; thus, we aimed to identify new surrogate risk factors to better reflect their atherosclerotic burden. Methods A total of 380 RA patients with carotid atherosclerosis data were analyzed in this prospective cohort study. The primary outcome was carotid plaque progression over the 3-year follow-up period. Risk parameters assessed for the progression of carotid plaque were categorized as demographics, traditional CVD risks, RA-related risks, and bone parameters. Results The progression of carotid plaque was associated with the level of rheumatoid factor (p = 0.025), serum C-terminal telopeptide of type-I collagen (CTX-I) (p = 0.014), and femur and distal radius bone mass density (BMD) (p = 0.007 and 0.004, respectively), as well as traditional CVD risk factors. In multivariable analyses, the bone parameters of serum CTX-I and distal radius BMD proved to be independent predictors of the progression of carotid plaque along with hyperlipidemia, smoking, and baseline carotid plaque (all, p < 0.05). Adding both serum CTX-I and distal radius BMD increased the carotid plaque progression prediction model’s percentage of explained variance from 24 to 30%. Conclusion High serum CTX-I and lower radius BMD, reflecting high bone turnover, were independent risk factors for the progression of carotid plaque in RA patients, implicating the direct or indirect role of bone metabolism on the atherosclerotic burden.

scholarly journals Radial BMD and serum CTX-I can Predict the Progression of Carotid Plaque in Rheumatoid Arthritis: A 3-year Prospective Cohort Study

2021 ◽  
Author(s):  
Seungwoo Han ◽  
Na-Ri Kim ◽  
Jong-Wan Kang ◽  
Jung-Su Eun ◽  
Young Mo Kang
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Cohort Study ◽  
Distal Radius ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Carotid Plaque ◽  
Plaque Progression ◽  
Bone Parameters ◽  
Atherosclerotic Burden

Abstract Objective. Patients with rheumatoid arthritis (RA) are almost twice as likely to develop cardiovascular disease (CVD) as those without. However, traditional CVD risks have been shown to underperform in RA patients; thus, we aimed to identify new surrogate risk factors to better reflect their atherosclerotic burden.Methods. A total of 380 RA patients with carotid atherosclerosis data were analyzed in this prospective cohort study. The primary outcome was carotid plaque progression over the 3-year follow-up period. Risk parameters assessed for the progression of carotid plaque were categorized as demographics, traditional CVD risks, RA-related risks, and bone parameters. Results. The progression of carotid plaque was associated with the level of rheumatoid factor (p = 0.025), serum C-terminal telopeptide of type-I collagen (CTX-I) (p = 0.014), and femur and distal radius bone mass density (BMD) (p = 0.007 and 0.004, respectively), as well as traditional CVD risk factors. In multivariable analyses, the bone parameters of serum CTX-I and distal radius BMD proved to be independent predictors of the progression of carotid plaque along with hyperlipidemia, smoking, and baseline carotid plaque (all, p < 0.05). Adding both serum CTX-I and distal radius BMD increased the carotid plaque progression prediction model’s percentage of explained variance from 24% to 30%.Conclusion. High serum CTX-I and lower radius BMD, reflecting high bone turnover, were independent risk factors for the progression of carotid plaque in RA patients, implicating the direct or indirect role of bone catabolism on the atherosclerotic burden.

The Natural Course and Risk Factors for Progression of Diabetic Retinopathy-KNDP Prospective Cohort Study

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1571-P
Author(s):  
HYUN UK MOON ◽  
JA YOUNG JEON ◽  
SOOJIN LEE ◽  
SEUNG JIN HAN ◽  
HAE JIN KIM ◽  
...  
Keyword(s):  
Risk Factors ◽  
Diabetic Retinopathy ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Natural Course

scholarly journals Prenatal Sociodemographic Factors Predicting Maltreatment of Children up to 3 Years Old: A Prospective Cohort Study Using Administrative Data in Japan

2021 ◽  
Vol 18 (5) ◽  
pp. 2505
Author(s):  
Aya Isumi ◽  
Kunihiko Takahashi ◽  
Takeo Fujiwara
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Child Maltreatment ◽  
Survey Data ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Characteristic Curve ◽  
Risk Scores ◽  
Prenatal Risk ◽  
Prenatal Risk Factors

Identifying risk factors from pregnancy is essential for preventing child maltreatment. However, few studies have explored prenatal risk factors assessed at pregnancy registration. This study aimed to identify prenatal risk factors for child maltreatment during the first three years of life using population-level survey data from pregnancy notification forms. This prospective cohort study targeted all mothers and their infants enrolled for a 3- to 4-month-old health check between October 2013 and February 2014 in five municipalities in Aichi Prefecture, Japan, and followed them until the child turned 3 years old. Administrative records of registration with Regional Councils for Children Requiring Care (RCCRC), which is suggestive of child maltreatment cases, were linked with survey data from pregnancy notification forms registered at municipalities (n = 893). Exact logistic regression was used for analysis. A total of 11 children (1.2%) were registered with RCCRC by 3 years of age. Unmarried marital status, history of artificial abortion, and smoking during pregnancy were significantly associated with child maltreatment. Prenatal risk scores calculated as the sum of these prenatal risk factors, ranging from 0 to 7, showed high predictive power (area under receiver operating characteristic curve 0.805; 95% confidence interval (CI), 0.660–0.950) at a cut-off score of 2 (sensitivity = 72.7%, specificity = 83.2%). These findings suggest that variables from pregnancy notification forms may be predictors of the risk for child maltreatment by the age of three.

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