scholarly journals Zoledronate-induced acute anterior uveitis: a three-case report and brief review of literature

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Xue Jin ◽  
Zhangxuan Shou ◽  
Yuhong Shao ◽  
Pingda Bian
Keyword(s):  
Case Report ◽  
Anterior Uveitis ◽  
Vision Loss ◽  
Bisphosphonate Therapy ◽  
Phase Reaction ◽  
Acute Anterior Uveitis ◽  
Blurred Vision ◽  
Treatment Regimens ◽  
Keratic Precipitates

Abstract Purpose This three-case report aims to highlight the ocular adverse effects induced by bisphosphonate therapy and to call clinicians’ attention. Methods Three cases of acute anterior uveitis secondary to the initial dose of zoledronate infusion were reported with focus on their symptoms, treatment regimens, and outcomes. A review of published reports provided a basis for discussion. Results Three cases of acute anterior uveitis were either bilateral or unilateral. They demonstrated typical manifestations of bisphosphonate-induced acute anterior uveitis such as eye pain, blurred vision, conjunctival and ciliary hyperemia, keratic precipitates, and flare in the anterior chamber. After topical corticosteroid-containing comprehensive treatments, these symptoms resolved completely without any vision loss and long-term sequelae. Conclusions Acute anterior uveitis may be part of the acute phase reaction induced by zoledronate. Patients should be informed of its symptoms in advance and be monitored closely during and after administration. Clinicians should have a good awareness of the zoledronate-associated acute anterior uveitis and to treat it in a prompt and appropriate manner.

scholarly journals Atypical Femoral Fracture during Long-term Bisphosphonate Therapy: A Case Report

2012 ◽  
Vol 61 (4) ◽  
pp. 795-798
Author(s):  
Kenichi Seo ◽  
Shinji Tomari ◽  
Yasumasa Ito ◽  
Tatsuya Yufu ◽  
Takahiro Yasuhara ◽  
...  
Keyword(s):  
Case Report ◽  
Femoral Fracture ◽  
Bisphosphonate Therapy ◽  
Atypical Femoral Fracture

scholarly journals Optic neuritis and acute anterior uveitis associated with influenza A infection: a case report

2017 ◽  
Vol Volume 10 ◽  
pp. 1-5 ◽  
Author(s):  
Hayate Nakagawa ◽  
Hidetaka Noma ◽  
Osamu Kotake ◽  
Ryosuke Motohashi ◽  
Kanako Yasuda ◽  
...  
Keyword(s):  
Case Report ◽  
Optic Neuritis ◽  
Anterior Uveitis ◽  
Influenza A ◽  
Acute Anterior Uveitis

scholarly journals When HIV Immunodeficiency and Heterochromia Confuse the Issue: Recurrent Zoster Uveitis Mistaken for Fuchs’ Uveitis

2021 ◽  
Author(s):  
Ioannis Papasavvas ◽  
Bruno Jeannin ◽  
Carle Pierre Herbort
Keyword(s):  
Case Report ◽  
Anterior Uveitis ◽  
Positive Patient ◽  
Hiv Positive ◽  
Laser Flare Photometry ◽  
Keratic Precipitates ◽  
Laser Flare ◽  
The Right

Purpose: We report a case with iris heterochromia misdiagnosed as Fuchs’ uveitis which finally turned out to be a unilateral zoster uveitis in an HIV-positive patient. Case Report: A 45-year old patient was seen for a recurrent right anterior uveitis treated with prednisolone 1% drops BID. The iris of the right eye was hypochromic and atrophic and several small granulomatous keratic precipitates (KPs) were present. After discontinuation of corticosteroid drops, severe uveitis developed with mutton-fat KPs, and laser flare photometry (LFP) increased from 20 to 50.3 ph/ms. He had presented with right zoster ophthalmicus two years earlier and HIV-serology revealed to be positive. Conclusion: Iris heterochromia is not a good disease-defining criterion for Fuch’s uveitis even when typical KPs are present and can lead to misdiagnosis. More reliable criteria including stellate KPs, low LFP values, absence of synechiae, vitreitis, and disc hyperfluorescence, all absent in this case, should be sought to confirm or exclude the diagnosis.

Anterior Uveitis and management in Ayurveda - A Case Study

2017 ◽  
Vol 2 (05) ◽  
Author(s):  
Nithyashree C. T. ◽  
Sujathamma K.
Keyword(s):  
Anterior Uveitis ◽  
Developed Countries ◽  
Treatment Modalities ◽  
Cystoid Macular Oedema ◽  
Recurrence Rates ◽  
Blurred Vision ◽  
Keratic Precipitates ◽  
Contemporary Science ◽  
Ayurvedic Treatment

Anterior uveitis is inflammation of the Uveal tissue from iris upto Pars plicata of ciliary body, which is a common cause for painful red eye. It usually affects people of 20 -50 years of age and account for 10 -15% of cases of legal blindness in developed countries. Depending on the clinical presentation it can be categorised as Iritis, Cyclitis or iridocyclitis. It is typically characterized by photophobia, pain, ciliary congestion, Blurred vision, Keratic precipitates, Aqueous flare and cells and often pooled with Auto immune diseases. If untreated, it can cause permanent visual loss and serious complications such as glaucoma, cataract, and cystoid macular oedema, Retinal detachment. Reducing the inflammation with the help of steroids, Immunosuppressant (topically, systematically) are the treatments indicated in contemporary science but these have their own side-effects and many entities are such that the recurrence rates are very high in spite of treatment or will be non-responsive. So it is coherent to adopt Ayurvedic treatment principles to resolve the ailment securely and to overcome the magnitudes of recurrence. The clinical features of Anterior Uveitis simulates to Pittaja and Raktaja Adhimanta to a greater extent and treatment modalities can be adopted based on Doshas and Samprapthi involved. In this paper, a special case report of a 51 years old male patient with Anterior Uveitis who showed marked improvement with Ayurvedic management is presented. The possible role of Ayurveda in its management and mode of action is also discussed here.

scholarly journals Case report: restored vision after ocular Closantel intoxication and blindness

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mohammad Reza Khalili ◽  
Athar Zareei
Keyword(s):  
Visual Acuity ◽  
Case Report ◽  
Visual Function ◽  
Vision Loss ◽  
Ocular Toxicity ◽  
Present Case Report ◽  
Hospital Arrival ◽  
Hand Motion ◽  
Complete Restoration

Abstract Background Closantel is the best-known anti-parasitic medicine for veterinarians, which is contraindicated in humans. After reviewing the literature on ocular toxicity following mistaken usage of Closantel in humans, this report was found as the first complete restoration of visual function after Closantel intoxication. This report could be useful in anticipating the possibility of a further improvement based on a dose-response relationship. An important point of this report is the apparent reversibility of the vision and Electrophysiological parameters after Closantel intoxication and blindness. To conclude, the present case report demonstrates the importance of immediate referral and management in Closantel intoxication to avoid the long-term adverse effects of drug on visual function. Case presentation A 47-year-old man mistakenly took about 20 cc of Closantel 5% (15.87 mg/kg). Four hours after mistaken usage of Closantel, he was transferred to the district hospital due to dizziness and nausea. His stomach was washed out immediately after hospital arrival. He was being hospitalized in that hospital for 3 days. Then, he was referred to our clinic due to progressive vision loss. Methylprednisolone acetate 250 mg was injected once on 5th day after taking Closantel. His vision was reducing gradually so low that he could only detect hand motion (HM) on the 14th day after taking Closantel. ERG test was requested. It showed an exclusive reduction in b-wave amplitude under photopic and scotopic conditions. Later, his vision surprisingly improved gradually and his visual acuity was fully restored on the 28th day after the incident. After 3 years, we checked him again. His visual acuity was 20/20 in both eyes and the patient did not have any problem and his ERG report was completely normal. Conclusions In low dose of Closantel and immediate referral, ocular toxicity could be resolved.

scholarly journals Probiotic Supplementation Improved Acute Anterior Uveitis of 3-Year Duration: A Case Report

2021 ◽  
Vol 22 ◽  
Author(s):  
Pasquale Napolitano ◽  
Mariaelena Filippelli ◽  
Luca D\'andrea ◽  
Marianna Carosielli ◽  
Roberto dell\'Omo ◽  
...  
Keyword(s):  
Case Report ◽  
Anterior Uveitis ◽  
Acute Anterior Uveitis ◽  
Probiotic Supplementation

scholarly journals Correction to: Treatment strategy for atypical ulnar fracture due to severely suppressed bone turnover caused by long-term bisphosphonate therapy: a case report and literature review

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Kensaku Abe ◽  
Hiroaki Kimura ◽  
Norio Yamamoto ◽  
Shingo Shimozaki ◽  
Takashi Higuchi ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Bone Turnover ◽  
Treatment Strategy ◽  
Bisphosphonate Therapy ◽  
Ulnar Fracture ◽  
Severely Suppressed Bone Turnover

An amendment to this paper has been published and can be accessed via the original article.

scholarly journals Unilateral Visual loss Due to Methanol Intoxication: A Case Report

2021 ◽  
Author(s):  
Hoorvash Faraji Dana ◽  
Nasim Zamani ◽  
Lida Shojaei Arani ◽  
Ali Faraji ◽  
Kiumars Bahmani
Keyword(s):  
Case Report ◽  
Visual Impairment ◽  
Visual Loss ◽  
Vision Loss ◽  
Blurred Vision ◽  
Methanol Intoxication ◽  
Methanol Poisoning

A 45-year-old man with bilateral blurred vision referred to toxicology department, after treatment he suffered from vision loss in left eye while his right eye was intact. Visual impairment due to methanol poisoning usually occurs bilaterally, but in our case was interestingly unilateral.

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