scholarly journals Unilateral Visual loss Due to Methanol Intoxication: A Case Report

2021 ◽  
Author(s):  
Hoorvash Faraji Dana ◽  
Nasim Zamani ◽  
Lida Shojaei Arani ◽  
Ali Faraji ◽  
Kiumars Bahmani
Keyword(s):  
Case Report ◽  
Visual Impairment ◽  
Visual Loss ◽  
Vision Loss ◽  
Blurred Vision ◽  
Methanol Intoxication ◽  
Methanol Poisoning

A 45-year-old man with bilateral blurred vision referred to toxicology department, after treatment he suffered from vision loss in left eye while his right eye was intact. Visual impairment due to methanol poisoning usually occurs bilaterally, but in our case was interestingly unilateral.

scholarly journals Reversible Total Vision Loss Caused by Severe Metformin-associated Lactic Acidosis: A Case Report

2021 ◽  
Vol 2 (5) ◽  
pp. 206-209
Author(s):  
Andrew Koons ◽  
Alexandra Amaducci ◽  
Kenneth Katz
Keyword(s):  
Diabetes Mellitus ◽  
Emergency Department ◽  
Case Report ◽  
Lactic Acidosis ◽  
Visual Loss ◽  
Vision Loss ◽  
Hospital Emergency Department ◽  
Type Ii ◽  
Hospital Emergency ◽  
Metformin Concentration

Introduction: Metformin is a biguanide used to treat diabetes mellitus (DM). Metformin-associated lactic acidosis (MALA) carries a high mortality and can occur in patients with renal failure from drug bioaccumulation. Reversible vision loss is a highly unusual, rarely reported complication of MALA. We present a case of a patient whose serum metformin concentration was unusually high and associated with vision loss. Case Report: A 60-year-old woman presented to an outside hospital emergency department with acute vision loss after being found at home confused, somnolent, and hypoglycemic, having last being seen normal two days prior. She reported vomiting and diarrhea during that time and a recently treated urinary tract infection. The visual loss resolved with continuous renal replacement therapy. Conclusion: This novel case of a patient with Type II DM prescribed metformin and insulin who developed reversible vision loss while suffering from MALA highlights the potential for vision loss in association with MALA.

scholarly journals Chorioretinal Folds in the Trabeculectomized Eye with Normal Intraocular Pressure after Phacoemulsification

Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 896
Author(s):  
Yi-Fen Lai ◽  
Ching-Long Chen ◽  
Ke-Hao Huang ◽  
Yi-Hao Chen
Keyword(s):  
Intraocular Pressure ◽  
Case Report ◽  
Visual Loss ◽  
Early Recognition ◽  
Open Angle Glaucoma ◽  
Eye Drops ◽  
Fundus Examination ◽  
Blurred Vision ◽  
Foveal Thickness ◽  
The Right

Background and Objectives: This case report discusses possible causes of chorioretinal fold (CRF) formation. Materials and Methods: A case report. Results: A 48-year-old man presented with a history of high myopia and primary open-angle glaucoma in both eyes. He underwent a trabeculectomy followed by phacoemulsification in both eyes. Two months later, he complained of blurred vision in the right eye. The intraocular pressure (IOP) was 17 mmHg in the left eye and 9 mmHg in the right eye. Refraction showed a hyperopic shift in both eyes. Slit-lamp examination showed a deep anterior chamber without cells and a well-functional bleb without leakage. Fundus examination revealed CRFs in the macula of the right eye. No papilledema, choroidal lesions, or other retinal lesions were found. Wrinkling of CRFs at the macula, an increase in central foveal thickness, and a fluid cleft were demonstrated by spectral-domain optical coherence tomography. After using steroid eye drops, the IOP in the right eye and refraction in both eyes recovered to the baseline level. Visual acuity improved in both eyes. Conclusions: CRFs in trabeculectomized eyes with normal IOP after phacoemulsification have not been reported. This case demonstrated that the trabeculectomized eye remains at risk of CRF formation, even if the IOP is normal without hypotony. The importance of a detailed fundus examination in patients with unexplained blurred vision may be necessary after having undergone these procedures. The early recognition of the cause of visual loss may facilitate immediate treatment and may avoid irreversible changes with permanent visual loss.

scholarly journals Rare occurrence of severe blindness and deafness in Friedreich ataxia: a case report

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Joana Damásio ◽  
Ana Sardoeira ◽  
Maria Araújo ◽  
Isabel Carvalho ◽  
Jorge Sequeiros ◽  
...  
Keyword(s):  
Case Report ◽  
Visual Impairment ◽  
Vision Loss ◽  
Severe Disease ◽  
Friedreich Ataxia ◽  
Sensorineural Deafness ◽  
Low Frequencies ◽  
Long Duration ◽  
Severe Vision Loss

Abstract Background Friedreich ataxia is the most frequent hereditary ataxia worldwide. Subclinical visual and auditory involvement has been recognized in these patients, with co-occurrence of severe blindness and deafness being rare. Case report We describe a patient, homozygous for a 873 GAA expansion in the FXN gene, whose first symptoms appeared by the age of 8. At 22 years-old he developed sensorineural deafness, and at 26 visual impairment. Deafness had a progressive course over 11 years, until a stage of extreme severity which hindered communication. Visual acuity had a catastrophic deterioration, with blindness 3 years after visual impairment was first noticed. Audiograms documented progressive sensorineural deafness, most striking for low frequencies. Visual evoked potentials disclosed bilaterally increased P100 latency. He passed away at the age of 41 years old, at a stage of extreme disability, blind and deaf, in addition to the complete phenotype of a patient with Friedreich ataxia of more than 30 years duration. Discussion Severe vision loss and extreme deafness has been described in very few patients with Friedreich ataxia. Long duration, severe disease and large expanded alleles may account for such an extreme phenotype; nonetheless, the role of factors as modifying genes warrants further investigation in this subset of patients.

scholarly journals Vision loss after accidental methanol intoxication: a case report

2013 ◽  
Vol 6 (1) ◽  
Author(s):  
Marilita M Moschos ◽  
Nikolaos S Gouliopoulos ◽  
Alexandros Rouvas ◽  
Ioannis Ladas
Keyword(s):  
Case Report ◽  
Vision Loss ◽  
Methanol Intoxication

scholarly journals Delirium And Visual Loss After İntravenous Ondansetron Application in a Pediatric Patient: A Case Report

2020 ◽  
pp. 1-2
Author(s):  
Muhammet Mesut Nezir Engin ◽  
◽  
Önder Kılıçaslan ◽  
Kenan Kocabay ◽  
◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Practice ◽  
Side Effects ◽  
Mental Disorder ◽  
Cancer Treatment ◽  
Cognitive Functions ◽  
Visual Loss ◽  
Vision Loss ◽  
Organic Mental Disorder ◽  
Short Period

Ondansetron is a selective 5-hydroxytryptamine receptor (5HT-3) antagonist caused by cancer treatment and put into clinical practice as an antiemetic for anesthesia-related nausea and vomiting. Delirium is an organic mental disorder that develops in a short period of time and manifests itself with impairments in various cognitive functions, especially consciousness. In this case report, we aimed to present the patient who presented to the another hospital due to vomiting, who received intravenous (IV) ondansetron treatment, followed by blurred consciousness and vision loss, and to draw attention to the side effects that may occur after ondansetron

scholarly journals Serous Retinal Detachment in Pre-eclampsia: Case Report and Literature Review

2020 ◽  
Vol 42 (11) ◽  
pp. 772-773
Author(s):  
Joana Teresa Botelho Vasconcelos Raposo ◽  
Bruna Carina Da Silva Melo ◽  
Nuno Filipe Bernardo Belo Maciel ◽  
Sara Dias Leite ◽  
Óscar Renato Coutinho Rebelo ◽  
...  
Keyword(s):  
Case Report ◽  
Retinal Detachment ◽  
Caesarean Delivery ◽  
Visual Loss ◽  
Rare Complication ◽  
Serous Retinal Detachment ◽  
Blurred Vision ◽  
Serous Macular Detachment ◽  
Choroidal Ischemia ◽  
Angiographic Findings

AbstractPre-eclampsia (PE) is an obstetric disease with a multifactorial cause that affects ∼ 5% of pregnant women. Vision can be affected with varying severity, and retinal detachment is a very rare complication. It tends to be bilateral, diagnosed postpartum, and more prevalent in women who are primiparous and/or undergo caesarean delivery. The condition typically resolves completely and rarely causes total visual loss in the affected women. Fluorescence angiographic findings support the hypothesis that retinal detachment in PE is secondary to choroidal ischemia from intense arteriolar vasospasm. The present article is related to a case of a 37-year-old pregnant woman who had PE associated with a progressive blurred vision, diagnosed by ophthalmology as serous macular detachment of the retina.

scholarly journals Bilateral putaminal hemorrhage related to methanol poisoning: a complication of hemodialysis? Case report

1995 ◽  
Vol 53 (3a) ◽  
pp. 485-487 ◽  
Author(s):  
Miguel Giudicissi Filho ◽  
Carlos V. M. Holanda ◽  
Nelson A. Nader ◽  
Sergio R. P. Gomes ◽  
Paulo H. F. Bertolucci
Keyword(s):  
Comparative Literature ◽  
Case Report ◽  
Literature Review ◽  
Retrograde Amnesia ◽  
Favorable Outcome ◽  
Methanol Intoxication ◽  
Methanol Poisoning ◽  
Visual Deficit ◽  
Putaminal Hemorrhage

A case of acute methanol intoxication is presented, in which bilateral putaminal hemorrhage developed after hemodialysis. Even though the patient was initially comatose and profoundly acidotic, favorable outcome was achieved, with long-term neurologic impairments essentially restricted to mild crural paraparesis, retrograde amnesia, and marked visual deficit. A comparative literature review is evaluated.

scholarly journals Case Report: Diagnosis of Late Spontaneous Intraocular Lens Dislocation on Point-of-care Ultrasound

2021 ◽  
Vol 5 (3) ◽  
pp. 332-334
Author(s):  
Alexandra Pizarro ◽  
Thompson Kehrl
Keyword(s):  
Case Report ◽  
Cataract Surgery ◽  
Intraocular Lens ◽  
Vision Loss ◽  
Imaging Modality ◽  
Point Of Care ◽  
Angle Closure ◽  
Point Of Care Ultrasound ◽  
Blurred Vision ◽  
Iol Dislocation

Introduction: Spontaneous intraocular lens (IOL) dislocation is a rare, but serious, complication following cataract surgery. Case Report: We report a case of patient with a remote history of cataract surgery presenting to the emergency department with monocular blurred vision. Ocular point-of-care ultrasound (POCUS) facilitated diagnosis of a late spontaneous IOL dislocation. Discussion: Prosthetic IOL dislocations are being reported with increasing frequency. Prompt recognition of IOL dislocation is essential to prevent secondary complications, including acute angle-closure glaucoma and retinal detachment, which can result in permanent vision loss. Conclusion: Point-of-care ultrasound is a rapid, noninvasive imaging modality for early detection of IOL dislocation to help guide management, improve patient outcomes, and mitigate long-term sequelae.

scholarly journals Zoledronate-induced acute anterior uveitis: a three-case report and brief review of literature

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Xue Jin ◽  
Zhangxuan Shou ◽  
Yuhong Shao ◽  
Pingda Bian
Keyword(s):  
Case Report ◽  
Anterior Uveitis ◽  
Vision Loss ◽  
Bisphosphonate Therapy ◽  
Phase Reaction ◽  
Acute Anterior Uveitis ◽  
Blurred Vision ◽  
Treatment Regimens ◽  
Keratic Precipitates

Abstract Purpose This three-case report aims to highlight the ocular adverse effects induced by bisphosphonate therapy and to call clinicians’ attention. Methods Three cases of acute anterior uveitis secondary to the initial dose of zoledronate infusion were reported with focus on their symptoms, treatment regimens, and outcomes. A review of published reports provided a basis for discussion. Results Three cases of acute anterior uveitis were either bilateral or unilateral. They demonstrated typical manifestations of bisphosphonate-induced acute anterior uveitis such as eye pain, blurred vision, conjunctival and ciliary hyperemia, keratic precipitates, and flare in the anterior chamber. After topical corticosteroid-containing comprehensive treatments, these symptoms resolved completely without any vision loss and long-term sequelae. Conclusions Acute anterior uveitis may be part of the acute phase reaction induced by zoledronate. Patients should be informed of its symptoms in advance and be monitored closely during and after administration. Clinicians should have a good awareness of the zoledronate-associated acute anterior uveitis and to treat it in a prompt and appropriate manner.

scholarly journals OP0149 VISUAL LOSS IN PATIENTS WITH GIANT CELL ARTERITIS TREATED WITH TOCILIZUMAB

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 95.2-95
Author(s):  
J. Amsler ◽  
I. Kysela ◽  
L. Christ ◽  
C. Tappeiner ◽  
L. Seitz ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Visual Impairment ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Visual Loss ◽  
Vision Loss ◽  
Laboratory Data ◽  
Favorable Effect ◽  
Reactive Protein ◽  
American College Of Rheumatology

Background:Whether Tocilizumab (TCZ) may prevent vision loss in Giant Cell Arteritis (GCA) to the same extent as glucocorticoids remains a key and unanswered question. A patient cohort observed over up to 8 years addresses this issue.Objectives:To investigate the frequency of vision loss/visual impariment in a GCA cohort treated with TCZ.Methods:In this observational monocentric study, the courses of 192 patients with GCA treated with TCZ between 01.01.2011 and 31.12.2018 were analyzed. Data were extracted from medical records and collected in a Clinical Trial Unit (CTU) - based registry. Demographic, clinical and laboratory data were analyzed.Results:192 patients with GCA were treated with TCZ; 121 (63%) were female, 112 (58%) fulfilled 1990 American College of Rheumatology (ACR) criteria, all others had large vessel vasculitis based on magnetic resonance-angiography (MRA). The cumulative duration of TCZ treatment was 3467 months; the median treatment duration was 13.8 (8.5; 22.8) months. At baseline, visual impairment was present in 71 (37%) and vision loss in 21 (7.8%) patients. Visual loss was associated with higher age (74 (70; 82) vs. 70 (63; 76) years; p=0.029), lower C-reactive protein at baseline (14.0 (3.5; 42.0) vs. 54.5 (21.0; 101.0) mg/l; p<0.001), cranial symptoms (p<0.0001), jaw claudication (p=0.030) and negative MRA of the aorta (p=0.020). Over the observed time span only one patient taking part in a clinical trial developed vision loss. In total 4 (2%) patients with vision impairment showed deterioration and 61 (32%) improvement.Conclusion:Collectively, our data suggest that TCZ is able to prevent visual loss and may have a favorable effect on visual impairment.Disclosure of Interests:Jennifer Amsler: None declared, Iveta Kysela: None declared, Lisa Christ Consultant of: BMS, Christoph Tappeiner: None declared, Luca Seitz: None declared, Godehard Scholz: None declared, Florian Kollert Employee of: Novartis, Stephan Reichenbach: None declared, Peter Villiger Consultant of: MSD, Abbvie, Roche, Pfizer, Sanofi, Speakers bureau: Roche, MSD, Pfizer

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