Electrophoretic Deposition of Titanium Oxide on Wollastonite Glass–Ceramic Scaffold for Tissue Engineering

2020 ◽  
Vol 29 (5) ◽  
pp. 2767-2782
Author(s):  
Kiana Karimi ◽  
Parvin Alizadeh ◽  
Hamid Abdoli
Keyword(s):  
Tissue Engineering ◽  
Titanium Oxide ◽  
Electrophoretic Deposition ◽  
Glass Ceramic ◽  
Ceramic Scaffold

scholarly journals Placenta Derived Mesenchymal Stem Cells Hosted on RKKP Glass-Ceramic: A Tissue Engineering Strategy for Bone Regenerative Medicine Applications

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Mario Ledda ◽  
Marco Fosca ◽  
Angela De Bonis ◽  
Mariangela Curcio ◽  
Roberto Teghil ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Regenerative Medicine ◽  
Glass Ceramic ◽  
Phase Distribution ◽  
Sol Gel ◽  
Pcr Analysis ◽  
Cycle Phase ◽  
Cell Delivery ◽  
Limiting Factor

In tissue engineering protocols, the survival of transplanted stem cells is a limiting factor that could be overcome using a cell delivery matrix able to support cell proliferation and differentiation. With this aim, we studied the cell-friendly and biocompatible behavior of RKKP glass-ceramic coated Titanium (Ti) surface seeded with human amniotic mesenchymal stromal cells (hAMSCs) from placenta. The sol-gel synthesis procedure was used to prepare the RKKP glass-ceramic material, which was then deposited onto the Ti surface by Pulsed Laser Deposition method. The cell metabolic activity and proliferation rate, the cytoskeletal actin organization, and the cell cycle phase distribution in hAMSCs seeded on the RKKP coated Ti surface revealed no significant differences when compared to the cells grown on the treated plastic Petri dish. The health of of hAMSCs was also analysed studying the mRNA expressions of MSC key genes and the osteogenic commitment capability using qRT-PCR analysis which resulted in being unchanged in both substrates. In this study, the combination of the hAMSCs’ properties together with the bioactive characteristics of RKKP glass-ceramics was investigated and the results obtained indicate its possible use as a new and interesting cell delivery system for bone tissue engineering and regenerative medicine applications.

Development of a novel 3D glass-ceramic scaffold for endometrial cell in vitro culture

2018 ◽  
Vol 44 (12) ◽  
pp. 14920-14924 ◽  
Author(s):  
Marta Súarez ◽  
Enrique Gómez ◽  
Antonio Murillo ◽  
Adolfo Fernández ◽  
Susana Carrocera ◽  
...  
Keyword(s):  
In Vitro Culture ◽  
Glass Ceramic ◽  
Endometrial Cell ◽  
Ceramic Scaffold

Fully Interconnected Globular Porous Biphasic Calcium Phosphate Ceramic Scaffold Facilitates Osteogenic Repair

2007 ◽  
Vol 361-363 ◽  
pp. 119-122 ◽  
Author(s):  
J.H. Lim ◽  
J.H. Park ◽  
Eui Kyun Park ◽  
Hae Jung Kim ◽  
Il Kyu Park ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Calcium Phosphate ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Bone Substitute ◽  
Biphasic Calcium Phosphate ◽  
Bone Defects ◽  
Calcium Phosphate Ceramic ◽  
Ceramic Scaffold ◽  
Porous Biphasic Calcium Phosphate

An appropriate scaffold, which provides structural support for transplanted cells and acts as a vehicle for the delivery of biologically active molecules, is critical for tissue engineering. We developed a fully interconnected globular porous biphasic calcium phosphate ceramic scaffold by adopting a foaming method, and evaluated its efficiency as a bone substitute and a scaffold for bone tissue engineering by in vitro and in vivo biocompatible analysis and its osteogenic healing capacity in rat tibial bone defects. They have spherical pores averaging 400um in diameter and interconnecting interpores averaging 70um in diameter with average 85% porosity. They elicited no cytotoxicity and noxious effect on cellular proliferation and osteoblastic differentiation during the cell-scaffold construct formation. Also the bone defects grafted with fully interconnected globular porous biphasic calcium phosphate ceramic blocks revealed excellent bone healing within 3 weeks. These findings suggest that the fully interconnected porous biphasic calcium phosphate scaffold formed by the foaming method can be a promising bone substitute and a scaffold for bone tissue engineering.

Preparation of Macroporous Glass-Ceramic Composites Containing β-TCP

2006 ◽  
Vol 11-12 ◽  
pp. 223-226
Author(s):  
Akiko Obata ◽  
Megumi Sasaki ◽  
Toshihiro Kasuga
Keyword(s):  
Tissue Engineering ◽  
Compressive Strength ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Glass Ceramic ◽  
Tricalcium Phosphate ◽  
Ceramic Composites ◽  
Calcium Pyrophosphate ◽  
Macroporous Glass ◽  
Glass Powders

A macroporous phosphate invert glass ceramic (PIGC) was prepared by dipping polymer sponges in the powder-slurry of the mother glass with a composition of 60CaO-30P2O-3TiO2- 7Na2O in mol%, and subsequent burning off the sponge at 850°C for 1 hr. The macroporous PIGC consists predominantly of ß-tricalcium phosphate (β-TCP) and ß-calcium pyrophosphate, and it has macropores of 500 μm in diameter and porosity of 83 %. Its compressive strength was estimated to be 160 kPa. The PIGC composite containing a large amount of β-TCP was also prepared by heating the mixture of Ca(OH)2 with the mother glass powders of the PIGC. Solubility of the composite was higher than PIGC. The macroporous PIGC and PIGC composite were expected to be applicable in high resorbable scaffolds for bone tissue engineering.

scholarly journals Bioactive Glass and Glass-Ceramic Scaffolds for Bone Tissue Engineering

Materials ◽  
2010 ◽  
Vol 3 (7) ◽  
pp. 3867-3910 ◽  
Author(s):  
Lutz-Christian Gerhardt ◽  
Aldo R. Boccaccini
Keyword(s):  
Tissue Engineering ◽  
Bioactive Glass ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Glass Ceramic
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