Pilot Study Examining the Frequency of Several Gene Polymorphisms Involved in Morphine Pharmacodynamics and Pharmacokinetics in a Morbidly Obese Population

2010 ◽  
Vol 21 (8) ◽  
pp. 1257-1264 ◽  
Author(s):  
Célia Lloret Linares ◽  
Aline Hajj ◽  
Christine Poitou ◽  
Guy Simoneau ◽  
Karine Clement ◽  
...  
2002 ◽  
Vol 12 (6) ◽  
pp. 759-764 ◽  
Author(s):  
Dimitri J. Koumanis ◽  
Nicolas V. Christou ◽  
Xiao Ling Wang ◽  
Brian M. Gilfix

Gene ◽  
2015 ◽  
Vol 566 (2) ◽  
pp. 189-193 ◽  
Author(s):  
Mohammed Salman ◽  
Shruti Dasgupta ◽  
A. Cholendra ◽  
P.N. Venugopal ◽  
G.L. Lakshmi ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Si-Jia Lee ◽  
Kelvin Howyow Quek

Transnasal Humidified Rapid Insufflation Ventilatory Exchange (THRIVE) is a relatively new noninvasive oxygenation technique with a broad range of applications. It is used in the treatment of type one respiratory failure, as a preoxygenation tool, as a rescue and temporising measure in difficult airways, and as step-down oxygen therapy in patients after extubation. Its use has also been described in laryngeal surgeries, but they mainly involved normal-weight subjects or were used as a bridging oxygenation therapy before definitive airway is secured. The major benefits of using THRIVE in obese subjects undergoing laryngeal surgery include a tubeless and uninterrupted surgical field. This advantage is especially crucial in obese patients as they tend to have limited oropharyngeal space, rendering a shared airway technically challenging for surgeons. However, concerns of potential difficult airway and shorter safe apnoeic time in the obese population limit its use. In this case, we report its use as the sole oxygenation strategy in a morbidly obese patient undergoing airway surgery. Our experience suggests that THRIVE can provide a conducive operating field and adequate oxygenation in short apnoeic laryngeal procedures in the obese population, without causing excessive hypercarbia.


2012 ◽  
Vol 42 (5) ◽  
pp. 151 ◽  
Author(s):  
Anika Daing ◽  
Sarvendra Vikram Singh ◽  
Charanjeet Singh Saimbi ◽  
Mohammad Akhlaq Khan ◽  
Srikanta Kumar Rath

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