Enzymatic glycosylation of menthol: optimization of synthesis and extraction processes using response surface methodology and biological evaluation of synthesized product

2022 ◽  
Author(s):  
Shafaq Nisar ◽  
Muhammad Asif Hanif ◽  
Muhammad Zahid ◽  
Abdul Ghaffar
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Biological Evaluation ◽  
Extraction Processes ◽  
Enzymatic Glycosylation

scholarly journals An Overview on the Use of Response Surface Methodology to Model and Optimize Extraction Processes in the Food Industry

2021 ◽  
Vol 9 (3) ◽  
pp. 745-754
Author(s):  
Vicente Amirpasha Tirado-Kulieva ◽  
Manuel Sánchez-Chero ◽  
Mario Villegas Yarlequé ◽  
Gretell Fiorela Villegas Aguilar ◽  
Gilberto Carrión-Barco ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Bioactive Compounds ◽  
Food Industry ◽  
Biological Activities ◽  
Food Products ◽  
Modeling And Optimization ◽  
Independent Variables ◽  
Extraction Processes ◽  
Food Processes

Response surface methodology (RSM) is a widely used tool for modeling and optimization for food processes. The objective of this review is to evaluate recent findings on the use of RSM in the extraction of compounds from agri-food products. First, the steps for the application of RSM were briefly detailed. According to the analysis performed, RSM is suitable because it evaluates the effects of the independent variables and their interactions on the responses, which is ideal for the optimization of different techniques for the extraction of multiple bioactive compounds and therefore, in the various studies, has allowed to significantly increase the yield and even the biological activities of the extracts; however, RSM has limitations and considering the complexity and dynamics of foods, the challenge is much greater. In this sense, it was determined that simultaneous use with other techniques is necessary in order to optimally describe the process and obtain more accurate results.

scholarly journals Subcritical Water Extraction of Epigallocatechin Gallate from Camellia sinensis and Optimization Study Using Response Surface Methodology

Processes ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 1028
Author(s):  
Nguyen Tuan Hiep ◽  
Hoang Thanh Duong ◽  
Dang Tuan Anh ◽  
Nguyen Hoai Nguyen ◽  
Do Quang Thai ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Green Tea ◽  
Camellia Sinensis ◽  
Subcritical Water ◽  
Epigallocatechin Gallate ◽  
Water Extraction ◽  
Fast Method ◽  
Subcritical Water Extraction ◽  
Extraction Processes

Background: Camellia sinensis is a plant whose leaves and buds are used to produce tea. With many medicinal activities already found, green tea has been consumed widely in the world. Methods: The subcritical water extraction (SWE) of epigallocatechin gallate (EGCG) from green tea leaves and the effect of the different extraction conditions are investigated by response surface methodology (RSM). Furthermore, the model of the extraction processes is reviewed for application at the industrial scale. Results: Based on the RSM data, the maximum yield of extraction is determined via optimizing different parameters of the extraction processes. Optimal conditions are as follows: extraction time of 6 min, extraction temperature at 120 °C, and a sample/solvent ratio of 1:40 g/mL. Under such conditions, the best yield of EGCG is 4.665%. Moreover, the model of the extraction processes, which can be utilized for industry scale purpose, indicates a good correlation with the experimental data. Conclusions: Overall, SWE is competent and environmental-friendly, and it is also a highly selective and fast method. SWE is a promising method to take the place of organic solvents used in the extraction of weak polar and even non-polar natural compounds. Further studies on the scale-up of the extraction processes are ongoing.

scholarly journals Overview on the Response Surface Methodology (RSM) in Extraction Processes

2016 ◽  
Vol 2 (1) ◽  
Author(s):  
Khairul Anwar Mohamad Said ◽  
Mohamed Afizal Mohamed Amin
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Response Prediction ◽  
Optimization Approach ◽  
Herbal Plants ◽  
Extraction Processes ◽  
Niche Area ◽  
The Relationship ◽  
Central Composite

Response Surface Methodology (RSM) is an optimization tool that can identify interrelationship between variables as being adopted by experiment/ research studies in food and herbal plants extraction niche area. This review discusses the optimization approach through utilization of research surface methodology either using central composite design or Box-Behnken method specifically in extraction processes. The use of analysis of variance (ANOVA) to evaluate the degree of accuracy held by the derived model is based on several responses. RSM helps to determine the best experimental design in order to identify the relationship between variables. This paper also discusses on the utilization of RSM to derive a model equation that later can be applied for response prediction and the determination of optimal conditions.

Optimization of Ultrasonic-Assisted Extraction of Embelin from Embelia ribes using Response Surface Methodology

Planta Medica ◽  
2013 ◽  
Vol 79 (10) ◽  
Author(s):  
M Mujeeb ◽  
S Alam ◽  
M Akhtar ◽  
AK Najmi ◽  
M Aqil ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Embelia Ribes ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction
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