Stabilizing polymorphic transitions of tristearin using diacylglycerols and sucrose polyesters

Erythropoietic protoporphyria (EPP) is characterized by toxic accumulation of the hydrophobic compound protoporphyrin (PP). Ferrochelatase-deficient ( fch/ fch) mice are an animal model for human EPP. Recently, we have demonstrated that the accumulation of another hydrophobic compound, unconjugated bilirubin, could effectively be treated by stimulation of fecal fat excretion. We investigated whether stimulation of fecal fat excretion enhanced the disposal of PP in fch/ fch mice. Fch/ fch mice were fed for 8 wk with a high-fat diet (16 wt% fat; control) or with the high-fat diet mixed with either a nonabsorbable fat (sucrose polyester) or the intestinal lipase inhibitor orlistat. The effects of the treatments on fecal excretion of fat and PP and on hepatic PP concentrations were compared with control diets. Fecal fat excretion in fch/ fch mice on a high-fat diet was higher than in mice on a low-fat diet (+149%, P < 0.05). Sucrose polyesters and orlistat increased fecal fat excretion even more, up to sixfold of control values. However, none of the different treatments affected fecal PP excretion or hepatic PP concentration. Treatment of fch/ fch mice with a high-fat diet, a nonabsorbable fat diet, or with orlistat increased the fecal excretion of fat but did not increase fecal PP excretion or decrease hepatic PP concentration. The present data indicate that accumulation of PP is not amenable to stimulation of fecal fat excretion.

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Polymorphic transitions of V-type amylose upon hydration and dehydration

Food Hydrocolloids ◽

10.1016/j.foodhyd.2021.107372 ◽

2021 ◽

pp. 107372

Author(s):

Jiayue Guo ◽

Gregory R. Ziegler ◽

Lingyan Kong

Keyword(s):

Polymorphic Transitions ◽

Hydration And Dehydration

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Mortality of Bemisia tabaci biotype B (sternorrhyncha: aleyrodidae) adults by aliphatic and aromatic synthetic sucrose esters

Brazilian Archives of Biology and Technology ◽

10.1590/s1516-89132008000600005 ◽

2008 ◽

Vol 51 (6) ◽

pp. 1115-1119 ◽

Cited By ~ 3

Author(s):

Mariangela Alves ◽

Maurício Boscolo ◽

Odair Aparecido Fernandes ◽

Maria Andréia Nunes

Keyword(s):

Bemisia Tabaci ◽

Chemical Control ◽

Control Method ◽

Sucrose Esters ◽

Sodium Dodecylsulphate ◽

Insecticidal Effect ◽

Spray Tower ◽

Sucrose Polyesters ◽

Biotype B ◽

Bemisia Tabaci Biotype B

The B-strain of Bemisia tabaci Gennadius is a key pest of several crops and chemical control is the main control method used by growers, although reduction in efficacy due to insecticide resistance has already been reported. The aim of this work was to investigate the insecticidal effect of an array of synthetic sucrose esters with the aliphatic and aromatic groups on whitefly adults. Sucrose butyrate, caprate, octanoate, palmitate, oleate, octaacetate, phthalate, benzoate, and sucrose diacetate hexaisobutyrate were tested. The solutions were prepared and applied on the adults caught on yellow sticky traps using the Potter spray tower. Long-chains sucrose aliphatic esters were more effective against the silverleaf whiteflies and the highest mortality was obtained with sucrose oleate and sucrose octanoate. Since these compounds were tensoactive, sodium dodecylsulphate was also tested for the comparison but no effect was observed. Sucrose butyrate and other aliphatic and aromatic sucrose polyesters showed negligible effect on the silverleaf whiteflies.

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The Effect of Pressure on Polymorphic Transitions of Solids

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1.10.513 ◽

1915 ◽

Vol 1 (10) ◽

pp. 513-516 ◽

Cited By ~ 5

Author(s):

P. W. Bridgman

Keyword(s):

Polymorphic Transitions ◽

Effect Of Pressure

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Effect of sucrose polyesters on crystallization rate of vegetable ghee: solid fat content study

Grasas y Aceites ◽

10.3989/gya.2003.v54.i4.218 ◽

2003 ◽

Vol 54 (4) ◽

Author(s):

Mohammad Ibrahim Nasir

Keyword(s):

Solid Fat Content ◽

Crystallization Rate ◽

Fat Content ◽

Solid Fat ◽

Sucrose Polyesters

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Contribution of C−H⋯π Interactions to Polymorphic Transitions of a Molecular Crystal with Disordered Fragments

10.26434/chemrxiv.14345843 ◽

2021 ◽

Author(s):

Takuya Taniguchi ◽

Daisuke Takagi ◽

Toru Asahi

Keyword(s):

High Temperature ◽

Single Crystal ◽

Intermolecular Interaction ◽

Molecular Crystal ◽

Interaction Analysis ◽

Polymorphic Transition ◽

Underlying Mechanism ◽

Polymorphic Transitions ◽

Π Interactions ◽

Β Phase

Polymorphic transition is important for the functionality of crystalline materials. However, the underlying mechanism remains unclear, especially when the crystal structure contains disordered fragments. We report that C−H⋯π interactions play an important role in polymorphic transitions in a molecular crystal with disordered fragments. The crystal has three phases, namely the a (< -80°C), β (-80-40°C), and γ (< 40°C) phases, which are reversible through single-crystal-to-single-crystal transformation in association with temperature change. Disorder of bulky tert-butyl substituents appears at high-temperature in the β and γ phases. Intermolecular interaction analysis based on Hirshfeld surfaces and related fingerprint plots revealed that the proportion of π⋯π interactions decreased, while that of C−H⋯π interactions increased, at the transition from a to β phase. The proportion of C−H⋯π interactions also increased at the transition from β to γ phase, but continuously decreased in the β phase due to elevated temperature. Intermolecular interaction energies clarified the contribution of C−H⋯π interactions to the stability of high-temperature crystal β and γ phases via polymorphic transitions. Our results potentially lead to design molecular crystals with polymorphic transitions.

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3-sensor array for hand held breath diagnostic tool

MRS Proceedings ◽

10.1557/opl.2013.146 ◽

2013 ◽

Vol 1533 ◽

Cited By ~ 2

Author(s):

P. Gouma ◽

S. Sood

Keyword(s):

Diagnostic Tool ◽

Sensor Array ◽

Gas Sensing ◽

Orthorhombic Phase ◽

Structural Transformations ◽

Polymorphic Transitions ◽

Heat Treated ◽

Gas Sensing Properties ◽

Resistive Sensor ◽

Resistance Value

ABSTRACTPolymorphic transitions in nanocrystalline metal oxides leads to structural transformations resulting in differing properties at varying operating temperatures. Nanocrystalline MoO3 transforms from a metastable monoclinic phase to stable orthorhombic phase when heat treated in the temperature range of 420C to 500C. Gas sensing results have shown that at 420C MoO3 is sensitive to Isoprene, a 450C it shows sensitivity to CO2 and to ammonia at 500C. DSC data has proved that MoO3 changes crystal structure to monoclinic at 420C and to orthorhombic at about485C. This confirms a correlation between structure and gas sensing properties of MoO3. Using this knowledge a hand-held diagnostic tool is developed to monitor specific breath gases which can be biomarkers for diseases. The device consists of three sensors, the read-out gives a real time resistance value for each resistive sensor which is stored in a microprocessor. This is a one of a kind handheld tool for disease detection using ceramic sensors as detectors for gases which are known to be biomarkers for diseases.

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