Probing the Combined Effect of Flunitrazepam and Lidocaine on the Stability and Organization of Bilayer Lipid Membranes. A Differential Scanning Calorimetry and Dynamic Light Scattering Study

2012 ◽  
Vol 66 (3) ◽  
pp. 461-475 ◽  
Author(s):  
Benjamín Caruso ◽  
Julieta M. Sánchez ◽  
Daniel A. García ◽  
Eneida Paula ◽  
María A. Perillo
Keyword(s):  
Differential Scanning Calorimetry ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Lipid Membranes ◽  
Combined Effect ◽  
Bilayer Lipid Membranes ◽  
Scanning Calorimetry ◽  
Bilayer Lipid ◽  
Scattering Study ◽  
The Stability

Novel Bionic Biomembrane Supported by Gold Nanoparticles/Cellulose Hybrid Films

2012 ◽  
Vol 84 ◽  
pp. 13-18 ◽  
Author(s):  
Zhi Ming Liu ◽  
Yuan Lin An ◽  
Wen Jian Wu
Keyword(s):  
Gold Nanoparticles ◽  
Aqueous Solutions ◽  
Lipid Membranes ◽  
Hybrid Film ◽  
Bilayer Lipid Membranes ◽  
Hybrid Films ◽  
Bilayer Lipid ◽  
Long Period ◽  
Highly Active ◽  
The Stability

As one of the main methods to study biomembranes, the construction of highly active bionic biomembrane systems is very important. Based on the hybrid film of gold nanoparticles and cellulose, a novel system of bionic biomembrane is demonstrated. The ratio effects of lecithin to cholesterin on the stability of bilayer lipid membranes are studied. Lipid solutions that can form stable membranes in the air and in some aqueous solutions are prepared. The bionic biomembranes composed of bilayer lipid membranes and hybrid films of gold nanoparticles and cellulose can be sustained for a long period in aqueous solutions. The bionic biomembranes also exhibit some interesting electrochemical properties.

Phase transitions of liposomes: When light meets heat

2021 ◽  
Author(s):  
C S Velez-Saboyá ◽  
J R Guzmán-Sepúlveda ◽  
Jesus Carlos Ruiz-Suárez
Keyword(s):  
Differential Scanning Calorimetry ◽  
Phase Transitions ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Membrane Thickness ◽  
Scanning Calorimetry ◽  
Contraction Process ◽  
Exothermic Process ◽  
Gel Phase ◽  
Derivatives Of

Abstract Phase transitions of liposomes are normally studied by differential scanning calorimetry (DSC). A suspension of liposomes is subjected to an increase (decrease) of temperature and when heat is absorbed (released), the liposomes transit from a gel (liquid) to a liquid (gel) phase. This endothermic (exothermic) process takes place at a temperature called the melting temperature Tm, which is distinctive of the type of lipids forming the vesicles. The vesicles, though, also modify their size in the transition. Indeed, the thickness of the membranes decreases (increases) because carbon tails misalign (align). Concomitant with the modifications in the membrane thickness, the diameter (D) of the liposomes changes too. Therefore, when they are inspected by light, the scattered signal carries information from such dilatation (contraction) process. We performed careful experiments using dynamic light scattering (DLS) as a function of temperature to detect the size changes of different liposomes. Gaussian fits of the derivatives of the D vs T curves coincide within 1% with thermograms, which hints to the possibility of performing thermodynamic studies of lipid systems employing light.

Effect of organic and inorganic ions on the lower critical solution transition and aggregation of PNIPAM

Soft Matter ◽  
2018 ◽  
Vol 14 (38) ◽  
pp. 7818-7828 ◽  
Author(s):  
Leonor Pérez-Fuentes ◽  
Delfi Bastos-González ◽  
Jordi Faraudo ◽  
Carlos Drummond
Keyword(s):  
Differential Scanning Calorimetry ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Inorganic Ions ◽  
Hofmeister Series ◽  
Scanning Calorimetry ◽  
Thermosensitive Polymer

We have studied the effect of different ions belonging to the extended Hofmeister series on the thermosensitive polymer poly(N-isopropylacrylamide) (PNIPAM), by combining Differential Scanning Calorimetry (DSC) and Dynamic Light Scattering (DLS).

INFLUENCE OF NANOPARTICLES OF $ \mathrm{CuO} $ ON THE STABILITY AND CONDUCTIVITY OF BLM

2018 ◽  
Vol 52 (1 (245)) ◽  
pp. 41-46
Author(s):  
A.L. Torosyan ◽  
G.V. Ananyan ◽  
V.B. Arakelyan
Keyword(s):  
Lipid Membranes ◽  
Cuo Nanoparticles ◽  
Bilayer Lipid Membranes ◽  
Electrical Field ◽  
Linear Tension ◽  
Bilayer Lipid ◽  
Nanoparticles Concentration ◽  
The Stability

This study aims to provide arguments for an increase in the stability of bilayer lipid membranes (BLM) in an electrical field in presence of $ \mathrm{CuO} $ nanoparticles. Moreover, the sustainability of BLM becomes more stable with increasing of nanoparticles concentration. It is shown that an increase in the stability of BLM in an electrical field is mainly due to an increase in the coefficient of linear tension of the edge of a pore, which is forming in BLM. It is shown as well, that the presence of nanoparticles of $ \mathrm{CuO} $ in the solution surrounding BLM leads to a decrease in the conductivity of the BLM.

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