scholarly journals The role of early adversity and cognitive vulnerability in postnatal stress and depression

Author(s):  
Agnes Bohne ◽  
Ragnhild Sørensen Høifødt ◽  
Dag Nordahl ◽  
Inger Pauline Landsem ◽  
Vibeke Moe ◽  
...  

AbstractThe purpose of the present study was to examine vulnerability factors in expecting parents that might lead to mental illness in the perinatal period. Specifically, we studied how parental early adversity, attentional bias to infant faces, repetitive negative thinking, and demographic factors, were associated with pre- and postnatal depressive symptoms and parenting stress. Participants were expecting parents taking part in the Northern Babies Longitudinal Study, where assessments were made both pre- and postnatally. Assessments included both questionnaires and cognitive tasks. About half of the participants received the Newborn Behavior Observation (NBO)-intervention after birth, between pre- and postnatal assessments. Results show that repetitive negative thinking was a significant predictor of both depressive symptoms and parenting stress, while education, social support, and parity came out as protective factors, especially in mothers. Parental early adversity had an indirect effect on postnatal depressive symptoms and parenting stress, mediated by prenatal and postnatal depressive symptoms, respectively. The NBO intervention did not affect the results, signifying the importance of early childhood adverse events and negative thinking on parents' postnatal adjustment and mood, even when an intervention is provided. In conclusion, repetitive negative thinking is a significant vulnerability factor independent of the presence of depressive symptoms, and health professionals must be aware of parents’ thinking style both during pregnancy and after birth.

2017 ◽  
Vol 5 (3) ◽  
pp. 522-536 ◽  
Author(s):  
Catherine A. Burrows ◽  
Kiara R. Timpano ◽  
Lucina Q. Uddin

Many high-functioning individuals with autism spectrum disorder (ASD) also experience depression and anxiety, yet little is known about mechanisms underlying this comorbidity. Repetitive negative thinking (RNT) about self-referential information is a transdiagnostic cognitive vulnerability factor that may account for the relationship between these two classes of symptoms. We propose a model where negative self-referential processing and cognitive inflexibility interact to increase risk for RNT, leading to internalizing problems in ASD. Examination of interactions within and between two well-characterized large-scale brain networks, the default mode network and the salience network, may provide insights into neurobiological mechanisms underlying RNT in ASD. We summarize previous literature supporting this model, emphasizing moving toward understanding RNT as a factor accounting for the high rates of internalizing problems in ASD. Future research avenues include understanding heterogeneity in clinical presentation and treating cognitive flexibility and RNT to reduce comorbid internalizing problems in ASD.


2021 ◽  
pp. 216770262110094
Author(s):  
Mina Stefanovic ◽  
Tabea Rosenkranz ◽  
Thomas Ehring ◽  
Edward R. Watkins ◽  
Keisuke Takano

A reciprocal relationship between repetitive negative thinking (RNT) and negative affect (NA) has been found in various types of psychopathology. Recent studies have suggested that the magnitude of this association can vary across time and individuals, which may inform future psychopathology. Here, we explored how these dynamics and interplays are manifested in student and general populations using a statistical clustering algorithm. Across three experience-sampling data sets, our clustering analyses consistently identified two groups of individuals; one group had a higher bidirectional association between RNT and NA (and also higher inertia) than the other group. Furthermore, a prospective analysis revealed that the group with the higher bidirectional association is at risk of developing depressive symptoms during the 3-month follow-up period if they had experienced high levels of NA over the experience-sampling phase. These findings suggest that the dysfunctional affective and cognitive dynamics would be a promising target of preventive intervention.


2020 ◽  
Vol 2 (4) ◽  
Author(s):  
Colette R. Hirsch ◽  
Frances Meeten ◽  
Calum Gordon ◽  
Jill M. Newby ◽  
Debra Bick ◽  
...  

Background Repetitive negative thinking (RNT; e.g., worry about the future, rumination about the past) and the tendency to interpret ambiguous information in negative ways (interpretation bias) are cognitive processes that play a maintaining role in anxiety and depression, and recent evidence has demonstrated that interpretation bias maintains RNT. In the context of perinatal mental health, RNT has received minimal research attention (despite the fact that it predicts later anxiety and depression), and interpretation bias remains unstudied (despite evidence that it maintains depression and anxiety which are common in this period). Method We investigated the relationship between RNT, interpretation bias and psychopathology (depression, anxiety) in a pregnant sample (n = 133). We also recruited an age-matched sample of non-pregnant women (n = 104), to examine whether interpretation bias associated with RNT emerges for ambiguous stimuli regardless of its current personal relevance (i.e., pregnancy or non-pregnancy-related). Results As predicted, for pregnant women, negative interpretation bias, RNT, depression and anxiety were all positively associated. Interpretation bias was evident to the same degree for material that was salient (pregnancy-related) and non-salient (general), and pregnant and non-pregnant women did not differ. RNT was associated with interpretation bias for all stimuli and across the full sample. Conclusion Our findings highlight the need to further investigate the impact of interpretation bias in pregnant women, and test the effectiveness of interventions which promote positive interpretations in reducing RNT in the perinatal period.


2019 ◽  
Vol 46 (6) ◽  
pp. E202-E210
Author(s):  
Patrick Pössel ◽  
Amanda Mitchell ◽  
Brooks Harbison ◽  
G. Rafael Fernandez-Botran

2021 ◽  
pp. 140349482110117
Author(s):  
Shefal Y Shorey ◽  
Esperanza D. Ng ◽  
Cornelia Y.I. Chee

Aims: The prevalence of perinatal anxiety and depressive symptoms have been speculated to increase during an infectious disease outbreak but remains unknown in the context of the COVID-19 situation. Therefore, this review aimed to examine the prevalence of antenatal and postnatal anxiety and depressive symptoms among pregnant women and postpartum mothers during the COVID-19 period. Methods: Six electronic databases were systematically searched for articles from November 2019 to December 2020. Twenty-six observational studies and brief reports were included in the meta-analysis. Results: Overall, the prevalence of anxiety was greater than depression in both antenatal and postnatal periods, and the prevalence of depression was higher in the antenatal period than the postnatal period. The pooled prevalence for antenatal anxiety symptoms, antenatal depressive symptoms and postnatal depressive symptoms were 40% (95% confidence intervals (CI): 0.27–0.52), 27% (95% CI: 0.20–0.33) and 17% (95% CI: 0.10–0.24), respectively. Europe (56%, 95% CI: 0.28–0.85) had significantly higher prevalence of antenatal anxiety than Asia (16%, 95% CI: 0.09–0.23). Conclusions: The heightened prevalence of perinatal psychological disorders served as an impetus for healthcare professionals and policy makers to ramp up their support and mitigation strategies for pregnant women and mothers in times of health crisis.


2020 ◽  
Vol 7 (1) ◽  
pp. 34-50
Author(s):  
Joshua J. Knabb ◽  
Veola E. Vazquez ◽  
Fernando L. Garzon ◽  
Kristy M. Ford ◽  
Kenneth T. Wang ◽  
...  

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