The millennial generation has been known as the most anxious and depressed one, due to lack of more physical attachment. During these COVID-19 times, these problem had been widened for everyone - many had been panic about the illness, the media had played an awful hole on it, creating a scenario of huge risk for lives and jobs. We are facing a perfect storm, where we are not allowed to do most of the recreation and healthie programs - like visit the ones beloved, go to gym, go to a party. The use of internet have a lot of misinformation about the pandemic and even physicians, scientists and health politicians overload us with useless information. It was really hard to identify what was important. In this situation, dealing with uncertainty, anxiety and depression had created a huge problem for physicians and psychologists. How to help and support that. There are many strategies that we have used. First to diminish the search of information over COVID-19, selecting one trustable source. Second, contact your beloved ones, if possible with video call on an everyday basis. Third, develop a routine of physical activities in order to keep your body health. Fourth try to develop a health pattern of food. Together they can diminish the chance of having anxiety and depression. But if you need support for a professional, it’s important to have teams of professional available to give attention to that issues. The very first is a phone support or internet support, by teams that could discuss the problems and develop a personal strategy to deal with this situation. But when that is not enough, we must have a consultation with a physician or a psychologist. The approach must discuss fillings, worries and how to plan this isolation times. Most of us have a hidden agenda and fear that must be addressed and at this time it is important to allow the patients to talk about freely, and to develop empathy with their worries. After that we can promote some activities to diminish the fillings of anxiety and depression.