scholarly journals Beclin-1 Expression is a Predictor of Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma and Correlated to Hypoxia-Inducible Factor (HIF)-1α Expression

2009 ◽  
Vol 15 (3) ◽  
pp. 487-493 ◽  
Author(s):  
Yongshun Chen ◽  
You Lu ◽  
Changli Lu ◽  
Lei Zhang
Keyword(s):  
Squamous Cell Carcinoma ◽  
Clinical Outcome ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Hypoxia Inducible Factor ◽  
Beclin 1

scholarly journals PAX5 gene as a novel methylation marker that predicts both clinical outcome and cisplatin sensitivity in esophageal squamous cell carcinoma

Epigenetics ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. 865-874 ◽  
Author(s):  
Keisuke Kurimoto ◽  
Masamichi Hayashi ◽  
Rafael Guerrero-Preston ◽  
Masahiko Koike ◽  
Mitsuro Kanda ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Clinical Outcome ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Methylation Marker ◽  
Cisplatin Sensitivity ◽  
Pax5 Gene

scholarly journals A three-protein signature and clinical outcome in esophageal squamous cell carcinoma

Oncotarget ◽  
2014 ◽  
Vol 6 (7) ◽  
pp. 5435-5448 ◽  
Author(s):  
Hui-Hui Cao ◽  
Shi-Yi Zhang ◽  
Jin-Hui Shen ◽  
Zhi-Yong Wu ◽  
Jian-Yi Wu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Clinical Outcome ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Protein Signature

Expression of p53 Protein in Esophageal Squamous Cell Carcinoma: Relation to Hypoxia-Inducible Factor-1α, Angiogenesis and Apoptosis

Pathobiology ◽  
2005 ◽  
Vol 72 (4) ◽  
pp. 179-185 ◽  
Author(s):  
Shigeru Kimura ◽  
Yasuhiko Kitadai ◽  
Toshio Kuwai ◽  
Shinji Tanaka ◽  
Jun Hihara ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
P53 Protein ◽  
Hypoxia Inducible Factor ◽  
Hypoxia Inducible Factor 1Α

scholarly journals Expression of hypoxia-inducible factor-1alpha in esophageal squamous cell carcinoma

2005 ◽  
Vol 96 (3) ◽  
pp. 176-182 ◽  
Author(s):  
Tomokazu Matsuyama ◽  
Kuniaki Nakanishi ◽  
Takuya Hayashi ◽  
Yutaka Yoshizumi ◽  
Satoshi Aiko ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Hypoxia Inducible Factor

scholarly journals The Postoperative Lymphocyte to Monocyte Ratio Change Predicts Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma Undergoing Curative Resection

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Qian Song ◽  
Jun-zhou Wu ◽  
Hui-fen Jiang ◽  
Sheng Wang ◽  
Shu-nv Cai
Keyword(s):  
Squamous Cell Carcinoma ◽  
Clinical Outcome ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Dynamic Change ◽  
Disease Free Survival ◽  
Prognostic Predictor ◽  
Lymphocyte To Monocyte Ratio ◽  
Curative Operation

Background. Postoperative lymphocyte to monocyte ratio (post-LMR) change (LMRc) reflects the dynamic change of balance between inflammatory reaction and immune reaction after curative operation. An elevated preoperative LMR (pre-LMR) has been shown to be a prognostic factor in patients with esophageal squamous cell carcinoma (ESCC), but the clinical value of the LMRc remains unknown. Methods. 674 patients in ESCC undergoing curative operation were enrolled in this study. LMRc (LMRc=pre‐LMR–post‐LMR) was counted on the basis of data within one week before and after operation. The median of LMRc was chosen to be the optimal cut-off value to evaluate the prognostic value of LMRc. Results. Kaplan-Meier curves revealed that LMRc≤1.59 was significantly associated with worse overall survival (OS) (P=0.003) and disease-free survival (DFS) (P=0.008). Multivariate analysis suggested that LMRc could serve as an independent prognostic predictor for both OS (P=0.006, HR=0.687, 95% CI 0.526-0.898) and DFS (P=0.003, HR=0.640, 95% CI 0.476-0.859). Conclusions. LMRc is a promising prognostic predictor for predicting the worse clinical outcome in patients with ESCC undergoing curative operation.

Sign in / Sign up

Export Citation Format

Share Document