scholarly journals Human Epididymis Protein 4 and Lewis y Enhance Chemotherapeutic Resistance in Epithelial Ovarian Cancer Through the p38 MAPK Pathway

2021 ◽  
Author(s):  
Jian Gao ◽  
Liancheng Zhu ◽  
Huiyu Zhuang ◽  
Bei Lin
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
P38 Mapk ◽  
Mapk Pathway ◽  
Chemotherapeutic Resistance ◽  
Human Epididymis Protein 4 ◽  
Human Epididymis ◽  
P38 Mapk Pathway ◽  
Lewis Y

1315 Clinical role of human epididymis protein 4 (HE4) in epithelial ovarian cancer

2009 ◽  
Vol 7 (2) ◽  
pp. 143
Author(s):  
E. Bandiera ◽  
M. Ragnoli ◽  
L. Zanotti ◽  
E. Bignotti ◽  
C. Romani ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Clinical Role ◽  
Human Epididymis Protein 4 ◽  
Human Epididymis

scholarly journals Utility of Comprehensive Serum Glycopeptide Spectra Analysis (CSGSA) for the Detection of Early Stage Epithelial Ovarian Cancer

Cancers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2374
Author(s):  
Koji Matsuo ◽  
Kazuhiro Tanabe ◽  
Masaru Hayashi ◽  
Masae Ikeda ◽  
Miwa Yasaka ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Epithelial Ovarian Cancer ◽  
Diagnostic Performance ◽  
Screening Tool ◽  
Early Stage ◽  
Cancer Antigen 125 ◽  
Cancer Antigen ◽  
Spectra Analysis ◽  
Human Epididymis Protein 4 ◽  
Human Epididymis

Comprehensive serum glycopeptide spectra analysis (CSGSA) evaluates >10,000 serum glycopeptides and identifies unique glycopeptide peaks and patterns via supervised orthogonal partial least-squares discriminant modeling. CSGSA was more accurate than cancer antigen 125 (CA125) or human epididymis protein 4 (HE4) for detecting early stage epithelial ovarian cancer. Combined CSGSA, CA125, and HE4 had improved diagnostic performance. Thus, CSGSA may be a useful screening tool for detecting early stage epithelial ovarian cancer.

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