A case report of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas and literature review

2010 ◽  
Vol 3 (4) ◽  
pp. 195-203 ◽  
Author(s):  
Yasuhiro Togawa ◽  
Akihiko Tonouchi ◽  
Tsuyoshi Chiku ◽  
Wataru Sano ◽  
Tomoko Doki ◽  
...  
2019 ◽  
Vol 80 (3) ◽  
pp. 585
Author(s):  
Tae Seop Choi ◽  
Jongmee Lee ◽  
Baek Hui Kim ◽  
Jae Woong Choi ◽  
Kyeong Ah Kim ◽  
...  

2019 ◽  
Vol 06 (01) ◽  
pp. 6-21
Author(s):  
Andreea Rusu ◽  
Simona Eliza Giusca ◽  
Delia Gabriela Ciobanu Apostol ◽  
Lidia Ionescu ◽  
Irina Draga Caruntu

2021 ◽  
Vol 11 (42) ◽  
pp. 74-80
Author(s):  
Ionut Tanase ◽  
Andra Virlan

Abstract We present a case of a 48-year-old male patient who was admitted in our clinic for right nasal obstruction, antero-posterior mucopurulent rhinorrhea, recurrent right micro-epistaxis, hyposmia, cacosmia and right hemicrania. ENT findings and CT scan detects proliferative, polylobate, vascularized tumor formation occupying the right nasal nostril, with muco-purulent secretions lining the tumor formation. The tumor pushes the intersinusal wall to the side and the nasal septum to the contralateral nostril. The apparent origin is at the level of the right middle nasal meatus, but we could not identify a clear limit from the nasopharynx lateral and posterior wall. Resection of the entire tumor formation was performed under endoscopic control. The histopathological outcome revealed undifferentiated carcinoma; immunohistochemical tests were performed and support the myoepithelial origins.


2021 ◽  
Vol 6 (4) ◽  
pp. 307-310
Author(s):  
Jyoti Parag Dekate ◽  
Manjula V Kelkeri ◽  
Gowri Garudadri

Undifferentiated carcinoma with osteoclastic giant cells is a distinctive rare neoplasm involving pancreas and rarely bile ducts. This neoplasm shows characteristic histologic features with variable admixture of mononuclear histiocytic cells, non- neoplastic osteoclastic giant cells and neoplastic mononuclear cell component. Though, this tumor has been shown to share genetic alterations with pancreatic ductal adenocarcinoma, clinically, it behaves unpredictably with a substantial proportion of patient showing prolonged survival period. We present a case of this rare pancreatic tumour with brief literature review discussing the key pathologic features, immunophenotype, genetic profile and clinical behavior. Undifferentiated carcinoma with osteoclastic giant cells is a rare neoplasm in pancreas which is believed to be of epithelial origin and shares genetic aberrations with ductal adenocarcinoma. Despite this, these tumours have better prognosis with prolonged survival period.


2018 ◽  
Vol 113 (Supplement) ◽  
pp. S736
Author(s):  
Rupesh Manam ◽  
Dhishna Chaudhary ◽  
Kevan Manraj ◽  
Lianne K. Cavell

HPB ◽  
2018 ◽  
Vol 20 ◽  
pp. S550
Author(s):  
M. Ahuja ◽  
S. Shah ◽  
R. Deshpande

2018 ◽  
Vol 51 ◽  
pp. 45-49 ◽  
Author(s):  
Masatsugu Hiraki ◽  
Kenji Kitahara ◽  
Atsushi Miyoshi ◽  
Hiroki Koga ◽  
Hiroaki Nakamura ◽  
...  

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