Intra-abdominal bleeding caused by amyloid transthyretin amyloidosis in the gastrointestinal tract: a case report

Author(s):  
Shinsei Yumoto ◽  
Koichi Doi ◽  
Takaaki Higashi ◽  
Yoshiya Shimao ◽  
Mitsuharu Ueda ◽  
...  
2015 ◽  
Vol 24 (2) ◽  
pp. 235-239 ◽  
Author(s):  
Jan Ulrych ◽  
Vladimir Fryba ◽  
Helena Skalova ◽  
Zdenek Krska ◽  
Tomas Krechler ◽  
...  

Heterotopic pancreas is a congenital pathology of the gastrointestinal tract, particularly rare in the esophagus. Both symptomatology and findings during preoperative examinations are non-specific and therefore do not often lead to an accurate diagnosis, which is usually revealed only by histopathological assessment of a resected specimen. We report an unusual case of a patient suffering from severe dysphagia caused by heterotopic pancreas in the distal esophagus with chronic inflammation and foci of premalignant changes. This article also reviews 14 adult cases of heterotopic pancreas in the esophagus previously reported in the literature, with the aim of determining the clinical features of this disease and possible complications including rare premalignant lesions and malignant transformation. Especially with regard to those complications, we suggest that both symptomatic and incidentally found asymptomatic lesions should be resected.


2021 ◽  
Author(s):  
Bahareh Ebrahimi ◽  
Seyed Vahid Hosseini ◽  
Neda Haghighat ◽  
Nader Moeinvaziri ◽  
Masoud Amini ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Faruk Karateke ◽  
Ebru Menekşe ◽  
Koray Das ◽  
Sefa Ozyazici ◽  
Pelin Demirtürk

Crohn's disease may affect any segment of the gastrointestinal tract; however, isolated duodenal involvement is rather rare. It still remains a complex clinical entity with a controversial management of the disease. Initially, patients with duodenal Crohn' s disease (DCD) are managed with a combination of antiacid and immunosuppressive therapy. However, medical treatment fails in the majority of DCD patients, and surgical intervention is required in case of complicated disease. Options for surgical management of complicated DCD include bypass, resection, or stricturoplasty procedures. In this paper, we reported a 33-year-old male patient, who was diagnosed with isolated duodenal Crohn’s diseases, and reviewed the surgical options in the literature.


2006 ◽  
Vol 130 (2) ◽  
pp. 201-204 ◽  
Author(s):  
Payal Kapur ◽  
Dinesh Rakheja ◽  
Michael Bastasch ◽  
Kyle H. Molberg ◽  
Venetia R. Sarode

Abstract Primary thymic mucinous adenocarcinoma is extremely rare; to our knowledge, only 2 cases have been reported to date. We describe a third case of primary mucinous adenocarcinoma of the thymus in a 41-year-old man who presented with an anterior mediastinal mass with subsequent metastasis to the lung. The initial diagnosis was of metastatic mucinous adenocarcinoma, but extensive clinical workup of the patient failed to reveal a primary tumor elsewhere in the body. The specific identification of mucinous adenocarcinoma as a primary thymic neoplasm can be difficult or impossible. Morphologic and immunophenotypic similarities to mucinous adenocarcinomas of the gastrointestinal tract can pose diagnostic challenges for surgical pathologists, especially in small biopsy specimens.


Author(s):  
Fareeha Farooqui ◽  
Sehrish Latif ◽  
Humera Naz Altaf ◽  
Sania Waseem ◽  
Sohaib Khan ◽  
...  

Abstract Mucinous cystadenoma is a rare tumor of appendix it accounts for only 0.4% of the gastrointestinal tract malignancies and is reported rarely in literature. Therefore the surgical management is not yet established. Here we report a case of a 65 year old female who presented with a dragging sensation and a feeling of mass in right iliac fossa. Her computed tomography (CT) suggested an abscess formation of the parietal peritoneum. She was planned for laparotomy and upon exploration a mass was found arising from tip of retroperitoneal appendix. Whole of the appendix was studded with mucoid material. Limited right hemicolectomy was performed and histopathology of appendix showed mucinous cystadenoma with no evidence of malignant changes. Patient remained uneventful and was discharged on 4th post operative day. The unusual presentation of retroperitoneal pseudomyxoma without any intraperitoneal pathology, prompted us to report this case. Continuous...


2016 ◽  
Vol 38 (2) ◽  
Author(s):  
Marco Gasparella ◽  
Maurizio Marzaro ◽  
Mario Ferro ◽  
Carlo Benetton ◽  
Vittorina Ghirardo ◽  
...  

Meckel’s diverticulum is a common anomaly of the gastrointestinal tract. The most common complications of Meckel’s diverticulum are inflammation, bleeding and obstruction. We present a 12-year-old boy with bowel obstruction due to phytobezoar in a Meckel’s diverticulum. We describe diagnostic difficulties and our surgery approach comparing it to the literature.


2017 ◽  
Vol 45 (12) ◽  
pp. 1137-1141 ◽  
Author(s):  
Takashi Kato ◽  
Shin Ichihara ◽  
Hiroko Gotoda ◽  
Shunji Muraoka ◽  
Terufumi Kubo ◽  
...  

Author(s):  
Anca Florian ◽  
Michael Bietenbeck ◽  
Anna Hüsing-Kabar ◽  
Matthias Schilling ◽  
Hartmut H Schmidt ◽  
...  

Abstract Background Hereditary or variant transthyretin amyloidosis (ATTRv) is a progressive disease manifesting with neuropathy and/or cardiomyopathy. An early and accurate diagnosis of cardiac amyloidosis is a prerequisite for timely and appropriate patient management, including anti-amyloid therapies, as it is associated with heart failure, conduction disease and arrhythmias, leading to reduced quality of life and early death. Case Summary We present the case of an ATTRv male patient presenting with a mixed amyloidosis phenotype (neuropathy and cardiomyopathy). Cardiac disease manifestation comprised tachyarrhythmias (atrial fibrillation) and conduction abnormalities (AV-block) in addition to segmental left ventricular (LV) hypertrophy (septal wall) due to regionally pronounced amyloid deposits in the basal LV myocardium. Interestingly, by means of serial CMR studies, we were able to demonstrate an impressive and unexpected improvement of cardiomyopathy findings within a relatively short period-of-time after implementation of genome-silencer therapies. Discussion This is our second case report that showed ATTRv cardiomyopathy reversal under anti-amyloid therapy—documented by multiparametric CMR. Our findings support the hypothesis that amyloid infiltration leading to cardiomyopathy is not an irreversible pathological process—but rather a dynamic one, that cannot only be stopped but even reversed (to a certain degree) by currently emerging anti-amyloid therapies. Moreover, the role of serial multi-parametric CMR imaging for surveillance of cardiomyopathy dynamics under these therapies is nicely illustrated.


Author(s):  
Snigdha Elaprolu ◽  
Gowri Sankar Marimuthu ◽  
Raghul Sekar ◽  
Sunil Kumar Saxena

<p class="abstract">Unusual foreign bodies in the digestive tract are common in psychiatric patients and children requiring screening of the entire gastrointestinal tract. We here report two cases of unusual ingested blunt foreign body in the upper digestive tract managed differently.</p>


Sign in / Sign up

Export Citation Format

Share Document