Clinical Impact of Nutritional Status and Energy Balance in Elderly Hospitalized Patients

The incidence of nosocomial yeast infections has increased markedly in recent decades, especially among the elderly. The present study was therefore initiated not only to determine the predictive value of oral colonization by yeasts for the onset of a nosocomial Candida infection in elderly hospitalized patients (>65 years), but also to clarify the factors that promote infection and to establish a relationship between the intensity of oral carriage and the onset of yeast infection. During this prospective cohort study, 256 patients (156 women and 100 men with a mean age of 83±8 years) were surveyed for yeast colonization or infection. Samples were collected every 4 days from day 0 to day 16 from four sites in the mouth, and intrinsic and extrinsic factors that might promote infection were recorded for each patient. Pulsed field gel electrophoresis was performed on Candida albicans isolates from all infected patients. Poor nutritional status was observed in 81 % of the patients and hyposalivation in 41 %. The colonization level was 67 % on day 0 (59 % C. albicans) and a heavy carriage of yeasts (>50 c.f.u.) was observed for 51 % of the patients. The incidence of nosocomial colonization reached 6·9 % on day 4 (6·1 % on day 8 and 2·7 % on day 12), and that of nosocomial infection was 3·7 % on day 4 (6·8 % on day 8, 11·3 % on day 12 and 19·2 % on day 16). Of the 35 patients infected, 57 % were suffering from oral candidiasis. The principal risk factors for colonization were a dental prosthesis, poor oral hygiene and the use of antibiotics. The risk factors for infection, in addition to those already mentioned for colonization, were endocrine disease, poor nutritional status, prolonged hospitalization and high colony counts. Genotyping revealed person-to-person transmission in two patients. Thus, this study demonstrates a significant association between oral colonization and the onset of yeast infections in elderly hospitalized patients. Therefore, oral samples should be collected at admission and antifungal treatment should be administered in cases of colonization, especially in patients presenting a heavy carriage of yeasts. Genotyping of the strains confirmed the possibility of person-to-person transmission.

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Anemia in elderly hospitalized patients: prevalence and clinical impact

Internal and Emergency Medicine ◽

10.1007/s11739-015-1197-5 ◽

2015 ◽

Vol 10 (5) ◽

pp. 581-586 ◽

Cited By ~ 24

Author(s):

Margherita Migone De Amicis ◽

Erika Poggiali ◽

Irene Motta ◽

Francesca Minonzio ◽

Giovanna Fabio ◽

...

Keyword(s):

Clinical Impact ◽

Hospitalized Patients ◽

Elderly Hospitalized Patients

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Differences in nutritional status and activities of daily living and mobility in elderly hospitalized patients with heart failure

ESC Heart Failure ◽

10.1002/ehf2.12393 ◽

2019 ◽

Vol 6 (2) ◽

pp. 344-350 ◽

Cited By ~ 2

Author(s):

Masahiro Kitamura ◽

Kazuhiro P. Izawa ◽

Masakazu Yaekura ◽

Yumi Mimura ◽

Hitomi Nagashima ◽

...

Keyword(s):

Heart Failure ◽

Nutritional Status ◽

Activities Of Daily Living ◽

Daily Living ◽

Hospitalized Patients ◽

Patients With Heart Failure ◽

Elderly Hospitalized Patients

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The Relationship between Nutrition and Cancer in Elderly Hospitalized Patients: A Retrospective Chart Analysis

10.21203/rs.3.rs-636627/v1 ◽

2021 ◽

Author(s):

Lina Yang ◽

Lan Wu

Keyword(s):

Nutritional Status ◽

Elderly Patients ◽

Cancer Patients ◽

Blood Parameters ◽

Hospitalized Patients ◽

Nutritional Risk ◽

Cancer Group ◽

Close Relationship ◽

The Relationship ◽

Elderly Hospitalized Patients

Abstract Background: The purpose of the present study was to retrospectively analyze the relationship between nutrition and cancer in elderly hospitalized patients. Methods: A total of 339 elderly patients were divided into cancer and non-cancer groups. Information regarding nutritional blood parameters (NBP), including TP, ALB, PA, TLC, and Hb; nutritional risk screening (NRS), including ADL, MNA-SF, WST; and polypharmacy was collected and analyzed.Results: Among the 339 patients, 94 (27.7%) were women, 81 (23.9%) were cancer patients, and 258 (76.1%) were non-cancer patients. Overall, 25.3% of patients were malnourished. Patients in the cancer group were younger, with higher rates of inflammation, lower rates of polypharmacy and swallow dysfunction, increased ADL, and decreased MNA-SF score. The BMI, TP, PA, Hb, and TLC were notably decreased in cancer patients. The MNA-SF score had a positive correlation with BMI, TP, ALB, PA, Hb, TLC, and ADL, but a negative correlation with CRP, WST score, polypharmacy, and age. Conclusion: There was a close relationship between nutritional status and cancer in elderly patients. Geriatric patients with cancer were more prone to a poor nutritional status. Nutritional screening, assessment, and intervention should be increased to improve the prognosis in cancer patients.

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