scholarly journals 3-Butenyl isothiocyanate: a hydrolytic product of glucosinolate as a potential cytotoxic agent against human cancer cell lines

2016 ◽  
Vol 53 (9) ◽  
pp. 3437-3445 ◽  
Author(s):  
Rohit Arora ◽  
Rakesh Kumar ◽  
Jyoti Mahajan ◽  
Adarsh P. Vig ◽  
Bikram Singh ◽  
...  
2011 ◽  
Vol 25 (12) ◽  
pp. 1770-1775 ◽  
Author(s):  
Suresh Awale ◽  
Thein Zaw Linn ◽  
Feng Li ◽  
Yasuhiro Tezuka ◽  
Aung Myint ◽  
...  

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
IO Mondranondra ◽  
A Suedee ◽  
A Kijjoa ◽  
M Pinto ◽  
N Nazareth ◽  
...  

2020 ◽  
Vol 17 (5) ◽  
pp. 345-351
Author(s):  
Syndla Premalatha ◽  
G. Rambabu ◽  
Islavathu Hatti ◽  
Dittakavi Ramachandran

A new series of 3-(3,4,5-trimethoxyphenyl)-5-(2-(5-arylbenzo[b]thiophen-3-yl)oxa zol-5- yl)isoxazole derivatives were designed and synthesized. All these derivatives were evaluated for their anticancer activity against various human cancer cell lines such as MCF-7 (breast cancer), A549 (lung cancer), DU-145 (prostate cancer) and MDA MB-231 (breast cancer)-four human cancer cell lines by using MTT assay. Here, etoposide was used as a standard reference drug and most of the compounds were exhibited good anticancer activity with respect to cell lines. Among all compounds, five compounds 11b, 11c, 11f, 11i and 11j showed more potent activity than standard drug, in which, compound 11f was the most promising compound.


Sign in / Sign up

Export Citation Format

Share Document