scholarly journals Enzymatic synthesis of polyphenol glycosides catalyzed by transglycosylation reaction of cyclodextrin glucanotransferase derived from Trichoderma viride

2018 ◽  
Vol 55 (8) ◽  
pp. 3026-3034
Author(s):  
Sohaib Nazir ◽  
Joko Sulistyo ◽  
Muhammad Iqbal Hashmi ◽  
Ai Ling Ho ◽  
Mohammad Shaheen Khan
2010 ◽  
Vol 3 ◽  
pp. BCI.S2768 ◽  
Author(s):  
Kei Shimoda ◽  
Hiroki Hamada

Curcumin 4‘- O-glucooligosaccharides were synthesized by a two step-enzymatic method using almond β-glucosidase and cyclodextrin glucanotransferase (CGTase). Curcumin was glucosylated to curcumin 4‘- O-β-D-glucopyranoside by almond β-glucosidase in 19% yield. Curcumin 4‘- O-β-D-glucopyranoside was converted into curcumin 4‘- O-β-glucooligosaccharides, i.e. 4‘- O-β-maltoside (51%) and 4‘- O-β-maltotrioside (25%), by further CGTase-catalyzed glycosylation. Curcumin 4‘- O-β-glycosides showed suppressive action on IgE antibody formation and inhibitory effects on histamine release from rat peritoneal mast cells.


Molecules ◽  
2018 ◽  
Vol 23 (6) ◽  
pp. 1271 ◽  
Author(s):  
José González-Alfonso ◽  
David Rodrigo-Frutos ◽  
Efres Belmonte-Reche ◽  
Pablo Peñalver ◽  
Ana Poveda ◽  
...  

2013 ◽  
Vol 774-776 ◽  
pp. 901-906
Author(s):  
Xin Zhi Cao ◽  
Jian Ming You ◽  
Kai Bin Lv

Gamma cyclodextrin was produced synthesized from beta cyclodextrin in the presence of glycyrrhizin, using Cyclodextrin glucanotransferase (EC 2.4.1.19) from AlkalophilicBacillus. The results showed that more than 32.7% of beta cyclodextrin substrate was converted to the corresponding gamma cyclodextrin under the following conditions, viz. 200 units enzyme/g of β-CD, 10mmol/L of β-CD concentration, 3% of glycyrrhizin concentration, 27 h of reaction time, 65°C of temperature and a reaction pH of 7.0.


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