Toxicity of low doses of ultrafine diesel exhaust particles on bovine brain microvessel endothelial cells

2014 ◽  
Vol 10 (3) ◽  
pp. 245-250 ◽  
Author(s):  
Young-Sook Choi ◽  
Sang-Yong Eom ◽  
Heejin Park ◽  
Syed F. Ali ◽  
Susan M. Lantz-McPeak ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Diesel Exhaust ◽  
Bovine Brain ◽  
Diesel Exhaust Particles ◽  
Low Doses ◽  
Exhaust Particles ◽  
Microvessel Endothelial Cells ◽  
Brain Microvessel

Role of diesel exhaust particles in the induction of allergic asthma to low doses of soybean

2020 ◽  
pp. 110337
Author(s):  
M. de Homdedeu ◽  
M.J. Cruz ◽  
S. Sánchez-Díez ◽  
S. Gómez-Ollés ◽  
I. Ojanguren ◽  
...  
Keyword(s):  
Allergic Asthma ◽  
Diesel Exhaust ◽  
Diesel Exhaust Particles ◽  
Low Doses ◽  
Exhaust Particles

scholarly journals Effect of Pluronic P85 on Amino Acid Transport in Bovine Brain Microvessel Endothelial Cells

2008 ◽  
Vol 4 (1) ◽  
pp. 35-46 ◽  
Author(s):  
Xiaobin Zhang ◽  
Daria Y. Alakhova ◽  
Elena V. Batrakova ◽  
Shu Li ◽  
Zhihui Yang ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Amino Acid ◽  
Amino Acid Transport ◽  
Bovine Brain ◽  
Acid Transport ◽  
Microvessel Endothelial Cells ◽  
Brain Microvessel ◽  
Pluronic P85

In Vitro Permeation Study With Bovine Brain Microvessel Endothelial Cells

2004 ◽  
pp. 77-87 ◽  
Author(s):  
Seong-Hee Park ◽  
Sung-Hack Lee ◽  
Yaming Su ◽  
Patrick J. Sinko
Keyword(s):  
Endothelial Cells ◽  
Bovine Brain ◽  
Permeation Study ◽  
In Vitro Permeation ◽  
Microvessel Endothelial Cells ◽  
Brain Microvessel

scholarly journals Diesel exhaust particles override natural injury-limiting pathways in the lung

2010 ◽  
Vol 299 (2) ◽  
pp. L263-L271 ◽  
Author(s):  
N. Chaudhuri ◽  
C. Paiva ◽  
K. Donaldson ◽  
R. Duffin ◽  
L. C. Parker ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Western Blotting ◽  
Diesel Exhaust ◽  
Diesel Exhaust Particles ◽  
Low Doses ◽  
Human Monocytes ◽  
Tlr Agonists ◽  
Low Concentrations ◽  
Exhaust Particles ◽  
Inflammatory Milieu

Induction of effective inflammation in the lung in response to environmental and microbial stimuli is dependent on cooperative signaling between leukocytes and lung tissue cells. We explored how these inflammatory networks are modulated by diesel exhaust particles (DEP) using cocultures of human monocytes with epithelial cells. Cocultures, or monoculture controls, were treated with DEP in the presence or absence of LPS or flagellin. Production of cytokines was explored by Western blotting and ELISA; cell signaling was analyzed by Western blotting. Here, we show that responses of epithelial cells to DEP are amplified by the presence of monocytes. DEP amplified the responses of cellular cocultures to very low doses of TLR agonists. In addition, in the presence of DEP, the responses induced by LPS or flagellin were less amenable to antagonism by the physiological IL-1 antagonist, IL-1ra. This was paralleled by the uncoupling of IL-1 production and release from monocytes, potentially attributable to an ability of DEP to sequester or degrade extracellular ATP. These data describe a model of inflammation where DEP amplifies responses to low concentrations of microbial agonists and alters the nature of the inflammatory milieu induced by TLR agonists.

Modulation of cellular adhesion in bovine brain microvessel endothelial cells by a decapeptide

1997 ◽  
Vol 747 (1) ◽  
pp. 103-113 ◽  
Author(s):  
Dhananjay Pal ◽  
Kenneth L Audus ◽  
Teruna J Siahaan
Keyword(s):  
Endothelial Cells ◽  
Cellular Adhesion ◽  
Bovine Brain ◽  
Microvessel Endothelial Cells ◽  
Brain Microvessel

The effect of protein binding on ivermectin uptake by bovine brain microvessel endothelial cells

1992 ◽  
Vol 16 (5) ◽  
pp. 365-377 ◽  
Author(s):  
K. L. Audus ◽  
S. R. Knaub ◽  
F. L. Guillot ◽  
J. M. Schaeffer
Keyword(s):  
Endothelial Cells ◽  
Protein Binding ◽  
Bovine Brain ◽  
Microvessel Endothelial Cells ◽  
Brain Microvessel
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