Collision-Induced Dissociation of Deprotonated Peptides. Relative Abundance of Side-Chain Neutral Losses, Residue-Specific Product Ions, and Comparison with Protonated Peptides

2017 ◽  
Vol 29 (3) ◽  
pp. 463-469 ◽  
Author(s):  
Yuxue Liang ◽  
Pedatsur Neta ◽  
Xiaoyu Yang ◽  
Stephen E. Stein
Keyword(s):  
Relative Abundance ◽  
Side Chain ◽  
Collision Induced Dissociation ◽  
Specific Product ◽  
Protonated Peptides ◽  
Product Ions ◽  
Deprotonated Peptides

COLLISIONS OF LONG-LIVED EXCITED IONS OF OXYGEN AND NITROGEN

1964 ◽  
Vol 42 (11) ◽  
pp. 2086-2101 ◽  
Author(s):  
William McGowan ◽  
Larkin Kerwin
Keyword(s):  
Cross Section ◽  
Cross Sections ◽  
Ion Beam ◽  
Collision Induced Dissociation ◽  
Ion Molecule Reactions ◽  
Collision Region ◽  
Mean Lifetime ◽  
New States ◽  
Product Ions

The role of some excited ions in laboratory ion–molecule reactions has been investigated, and their possible importance in the upper atmosphere considered. The mass spectrometer techniques of Aston banding and of comparing I.P. curves of parent and product ions have been applied to studies of collision-induced dissociation and charge exchange of oxygen and nitrogen in their parent gas. In every case studied, cross sections depended markedly upon the presence in the ion beam of ions in metastable or long-lived radiative states. In order that an ion reach the collision region, it had to have a mean lifetime greater than 3 μsec.The a 4Πu and b 4Σg excited states of O2+ were identified in the collision[Formula: see text]Higher states of O2+, which have not as yet been identified spectroscopically, were found in the collision[Formula: see text]The thresholds of these new states are 23.9, 27.9, 31.3, and 34.1 eV with an uncertainty ±0.2 eV. From the collision-induced dissociation of N2+, the A 2Πu and the [Formula: see text] states have been identified. Also, the reported transfer of the ν = 3 level of the B [Formula: see text] to the ν = 14 level of the A 2Πu was found.The cross section for 10/01 charged exchange of N2+ in N2 exhibited a marked decrease as excited-state ions diluted the beam. The 10/01 collisions of N+ in N2 and O+ in O2 exhibited an increase in cross section as metastables were added to the parent ion beam. The 10/20 reaction of O2+ in O2 was also observed to depend on excited O2+ ions.

scholarly journals Dehydration versus deamination of N-terminal glutamine in collision-induced dissociation of protonated peptides

2007 ◽  
Vol 18 (1) ◽  
pp. 27-36 ◽  
Author(s):  
Pedatsur Neta ◽  
Quan -Long Pu ◽  
Lisa Kilpatrick ◽  
Xiaoyu Yang ◽  
Stephen E. Stein
Keyword(s):  
Collision Induced Dissociation ◽  
Protonated Peptides

Collision-Induced Dissociations of Deprotonated Peptides. Dipeptides Containing Asn, Arg and Lys

1993 ◽  
Vol 46 (5) ◽  
pp. 693 ◽  
Author(s):  
RJ Waugh ◽  
JH Bowie ◽  
ML Gross
Keyword(s):  
Collisional Activation ◽  
Mass Spectra ◽  
Fast Atom Bombardment ◽  
Side Chain ◽  
Deprotonated Peptides

The presence and position of Asn, Arg and Lys residues in dipeptides may be determined from a consideration of the collisional activation mass spectra of the (M-H)- ions formed by fast atom bombardment. All spectra show the basic dipeptide cleavage, i.e. NH2CH(R1)CONHCH(R2)CO2- → NH2C(R1)CONHCH(R2)CO2H → NH2C(R1)=C=O + -NHCH(R2)CO2H. There are a number of fragmentations characteristic of a particular α side chain: for example, Arg loses HN=C=NH (42 u).

Competitive McLafferty-type rearrangements of sodium adduct of anti-2,3-dihydroxy-1-phenylpentane-1,4-dione compounds in tandem mass spectrometry

2018 ◽  
Vol 24 (6) ◽  
pp. 437-441 ◽  
Author(s):  
Xiayan Zhang ◽  
Xu Xu ◽  
Xinmeng Chen ◽  
Lin Chen ◽  
Xiaoying Xu ◽  
...  
Keyword(s):  
Density Functional ◽  
Mass Difference ◽  
Fragmentation Pathway ◽  
Density Functional Theory Calculations ◽  
Sodium Cation ◽  
Membered Ring ◽  
Collision Induced Dissociation ◽  
Sodium Adducts ◽  
Main Fragmentation Pathway ◽  
Product Ions

Sodium adducts of anti-2,3-dihydroxy-1-phenylpentane-1,4-dione compounds with different substituents were studied by collision-induced dissociation. McLafferty-type rearrangements preceding fragmentation were found as their main fragmentation pathway. Coordination of sodium cation to the oxygen functions may either lead to formation of a five-membered or a six-membered ring. Two McLafferty-type rearrangement product ions exhibiting a mass difference of 2 u indicated that two competitive McLafferty-type rearrangements through a six-membered ring coordination occurred. Relative abundances of the corresponding product ions were studied by energy-resolved collision-induced dissociation experiments and density functional theory calculations. Furthermore, the influence of different substituents was probed.

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