scholarly journals Current Methods and Caveats to Risk Factor Assessment in Cutaneous Squamous Cell Carcinoma (cSCC): A Narrative Review

2022 ◽  
Author(s):  
Aaron S. Farberg ◽  
Alison L. Fitzgerald ◽  
Sherrif F. Ibrahim ◽  
Stan N. Tolkachjov ◽  
Teo Soleymani ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Narrative Review ◽  
Risk Factor Assessment

scholarly journals Persistence of Betapapillomavirus Infections as a Risk Factor for Actinic Keratoses, Precursor to Cutaneous Squamous Cell Carcinoma

2009 ◽  
Vol 69 (23) ◽  
pp. 8926-8931 ◽  
Author(s):  
Elsemieke I. Plasmeijer ◽  
Rachel E. Neale ◽  
Maurits N.C. de Koning ◽  
Wim G.V. Quint ◽  
Penelope McBride ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Actinic Keratoses

scholarly journals Outdoor work as a risk factor for high-grade cutaneous squamous cell carcinoma of the head and neck

2018 ◽  
Vol 35 (4) ◽  
pp. 408-412
Author(s):  
Mateusz Szewczyk ◽  
Jakub Pazdrowski ◽  
Paweł Golusiński ◽  
Aleksandra Dańczak-Pazdrowska ◽  
Mariola Pawlaczyk ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Cutaneous Squamous Cell Carcinoma ◽  
High Grade ◽  
Outdoor Work

Oral squamous cell carcinoma: epidemiological study and risk factor assessment based on a 39-year series

2020 ◽  
Vol 49 (12) ◽  
pp. 1525-1534 ◽  
Author(s):  
A. Capote-Moreno ◽  
P. Brabyn ◽  
M.F. Muñoz-Guerra ◽  
J. Sastre-Pérez ◽  
V. Escorial-Hernandez ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Epidemiological Study ◽  
Squamous Cell ◽  
Risk Factor Assessment

scholarly journals Enhanced metastatic risk assessment in cutaneous squamous cell carcinoma with the 40-gene expression profile test

2021 ◽  
Author(s):  
Sherrif F Ibrahim ◽  
Julia M Kasprzak ◽  
Mary A Hall ◽  
Alison L Fitzgerald ◽  
Jennifer J Siegel ◽  
...  
Keyword(s):  
Gene Expression ◽  
Squamous Cell Carcinoma ◽  
Risk Factor ◽  
Cell Carcinoma ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Squamous Cell ◽  
Cox Regression ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Primary Tumors

Aim: To clinically validate the 40-gene expression profile (40-GEP) test for cutaneous squamous cell carcinoma patients and evaluate coupling the test with individual clinicopathologic risk factor-based assessment methods. Patients & methods: In a 33-site study, primary tumors with known patient outcomes were assessed under clinical testing conditions (n = 420). The 40-GEP results were integrated with clinicopathologic risk factors. Kaplan–Meier and Cox regression analyses were performed for metastasis. Results: The 40-GEP test demonstrated significant prognostic value. Risk classification was improved via integration of 40-GEP results with clinicopathologic risk factor-based assessment, with metastasis rates near the general cutaneous squamous cell carcinoma population for Class 1 and ≥50% for Class 2B. Conclusion: Combining molecular profiling with clinicopathologic risk factor assessment enhances stratification of cutaneous squamous cell carcinoma patients and may inform decision-making for risk-appropriate management strategies.

Sign in / Sign up

Export Citation Format

Share Document