Synthesis of polyvinyl alcohol hydrogel grafted by modified Fe3O4 nanoparticles: characterization and doxorubicin delivery studies

2017 ◽  
Vol 26 (5) ◽  
pp. 313-322 ◽  
Author(s):  
Mojtaba Abasian ◽  
Vahid Hooshangi ◽  
Peyman Najafi Moghadam
Keyword(s):  
Polyvinyl Alcohol ◽  
Fe3o4 Nanoparticles ◽  
Doxorubicin Delivery ◽  
Nanoparticles Characterization

scholarly journals One-pot Synthesis and Surface Modification of Fe3O4 Nanoparticles Using Polyvinyl Alcohol by Coprecipitation and Ultrasonication Methods

2018 ◽  
Vol 299 ◽  
pp. 012066 ◽  
Author(s):  
Aditya D Nugraha ◽  
Ika O Wulandari ◽  
L B Hutami Rahayu ◽  
Imam Riva’i ◽  
D J Djoko H Santojo ◽  
...  
Keyword(s):  
Surface Modification ◽  
Polyvinyl Alcohol ◽  
Fe3o4 Nanoparticles ◽  
One Pot ◽  
One Pot Synthesis

scholarly journals Ex-Situ Synthesis of Polyvinyl alcohol(PVA)-coated Fe3O4 Nanoparticles by Coprecipitation-Ultrasonication Method

2018 ◽  
Vol 299 ◽  
pp. 012065 ◽  
Author(s):  
Imam Riva’i ◽  
Ika Oktavia Wulandari ◽  
Hermin Sulistyarti ◽  
Akhmad Sabarudin
Keyword(s):  
Polyvinyl Alcohol ◽  
Fe3o4 Nanoparticles ◽  
Ex Situ

scholarly journals Effect of Stirring Speed on Characteristics of Fe3O4 Nanoparticles Coated with Polyvinyl Alcohol and Glutaldehyde as a Crosslinker

Natural-B ◽  
2018 ◽  
Vol 004 (03) ◽  
pp. 127-134 ◽  
Author(s):  
Lale Budi Hutami Rahayu ◽  
Ika Oktavia Wulandari ◽  
D. J. Djoko H. Santjojo ◽  
Akhmad Sabarudin
Keyword(s):  
Polyvinyl Alcohol ◽  
Fe3o4 Nanoparticles

scholarly journals Dual-Functional Iron Oxide Nanoparticles Coated with Polyvinyl Alcohol/5-Fluorouracil/Zinc-Aluminium-Layered Double Hydroxide for a Simultaneous Drug and Target Delivery System

Polymers ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 855
Author(s):  
Mona Ebadi ◽  
Saifullah Bullo ◽  
Kalaivani Buskaran ◽  
Mohd Zobir Hussein ◽  
Sharida Fakurazi ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Iron Oxide ◽  
Polyvinyl Alcohol ◽  
Iron Oxide Nanoparticles ◽  
Layered Double Hydroxide ◽  
Delivery System ◽  
Fe3o4 Nanoparticles ◽  
Cancer Drug ◽  
Oxide Nanoparticles ◽  
Double Hydroxide

Iron oxide nanoparticles are suitable for biomedical applications owing to their ability to anchor to various active agents and drugs, unique magnetic properties, nontoxicity, and biocompatibility. In this work, the physico-chemical and magnetic properties, as well as the cytotoxicity, of Fe3O4 nanoparticles coated with a polymeric carrier and loaded with a 5-fluorouracil (5-FU) anti-cancer drug are discussed. The synthesized Fe3O4 nanoparticles were coated with polyvinyl alcohol and Zn/Al-layered double hydroxide as the drug host. The XRD, DTA/TG, and FTIR analyzes confirmed the presence of the coating layer on the surface of nanoparticles. The results showed a decrease in saturation magnetization of bare Fe3O4 nanoparticles after coating with the PVA/5FU/Zn/Al-LDH layer. In addition, the presence of the coating prevented the agglomeration of nanoparticles. Furthermore, the pseudo-second-order equation governed the kinetics of drug release. Finally, the coated nanoparticles showed stronger activity against liver cancer cells (HepG2) compared to that of the naked 5-FU drug, and displayed no cytotoxicity towards 3T3 fibroblast cell lines. The results of the present study demonstrate the potential of a nano delivery system for cancer treatment.

scholarly journals Effect of Stirring Speed on Characteristics of Fe3O4 Nanoparticles Coated with Polyvinyl Alcohol and Glutaldehyde as a Crosslinker

Natural-B ◽  
2018 ◽  
Vol 4 (3) ◽  
pp. 127-134
Author(s):  
Lale Budi Hutami Rahayu ◽  
Ika Oktavia Wulandari ◽  
D.J Djoko H. Santjojo ◽  
Akhmad Sabarudin
Keyword(s):  
Polyvinyl Alcohol ◽  
Fe3o4 Nanoparticles
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