scholarly journals Improvement of Intranasal Drug Delivery with Intravail® Alkylsaccharide Excipient as a Mucosal Absorption Enhancer Aiding in the Treatment of Conditions of the Central Nervous System

Drugs in R&D ◽  
2021 ◽  
Author(s):  
Adrian L. Rabinowicz ◽  
Enrique Carrazana ◽  
Edward T. Maggio
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Nervous System ◽  
Absorption Enhancer ◽  
Intranasal Drug Delivery ◽  
Mucosal Absorption ◽  
The Central Nervous System

Intranasal Drug Delivery to the Central Nervous System: Present Status and Future Outlook

2013 ◽  
Vol 19 (3) ◽  
pp. 510-526 ◽  
Author(s):  
Seyed Khosrow Tayebati ◽  
Innocent Ejike Nwankwo ◽  
Francesco Amenta
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Nervous System ◽  
Present Status ◽  
Future Outlook ◽  
Intranasal Drug Delivery ◽  
The Central Nervous System

Intranasal Drug Delivery to the Central Nervous System: Present Status and Future Outlook

2012 ◽  
Vol 19 (3) ◽  
pp. 510-526 ◽  
Author(s):  
Seyed Khosrow Tayebati ◽  
Innocent Ejike Nwankwo ◽  
Francesco Amenta
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Nervous System ◽  
Present Status ◽  
Future Outlook ◽  
Intranasal Drug Delivery ◽  
The Central Nervous System

Nanoparticle-mediated Drug Delivery Systems (DDS) in the Central Nervous System

2016 ◽  
Vol 21 (3) ◽  
pp. 272-283 ◽  
Author(s):  
Guilong Zhang ◽  
Lukui Chen ◽  
Xiaoyuan Guo ◽  
Ahsan Khan ◽  
Yuchun Gu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Nervous System ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
The Central Nervous System

scholarly journals Nanoparticulate Systems for Drug Delivery and Targeting to the Central Nervous System

2010 ◽  
Vol 17 (6) ◽  
pp. 670-677 ◽  
Author(s):  
Emanuela Fabiola Craparo ◽  
Maria Luisa Bondì ◽  
Giovanna Pitarresi ◽  
Gennara Cavallaro
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Nervous System ◽  
The Central Nervous System ◽  
Nanoparticulate Systems

scholarly journals Interventional MRI-guided catheter placement and real time drug delivery to the central nervous system

2016 ◽  
Vol 16 (6) ◽  
pp. 635-639 ◽  
Author(s):  
Seunggu J. Han ◽  
Krystof Bankiewicz ◽  
Nicholas A. Butowski ◽  
Paul S. Larson ◽  
Manish K. Aghi
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Nervous System ◽  
Real Time ◽  
Interventional Mri ◽  
Catheter Placement ◽  
The Central Nervous System ◽  
Mri Guided

scholarly journals Convection-enhanced delivery to the central nervous system

2015 ◽  
Vol 122 (3) ◽  
pp. 697-706 ◽  
Author(s):  
Russell R. Lonser ◽  
Malisa Sarntinoranont ◽  
Paul F. Morrison ◽  
Edward H. Oldfield
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Clinical Trials ◽  
Nervous System ◽  
Convective Flow ◽  
Clinical Applications ◽  
Systemic Delivery ◽  
Convection Enhanced Delivery ◽  
The Central Nervous System ◽  
Real Time Tracking

Convection-enhanced delivery (CED) is a bulk flow–driven process. Its properties permit direct, homogeneous, targeted perfusion of CNS regions with putative therapeutics while bypassing the blood-brain barrier. Development of surrogate imaging tracers that are co-infused during drug delivery now permit accurate, noninvasive real-time tracking of convective infusate flow in nervous system tissues. The potential advantages of CED in the CNS over other currently available drug delivery techniques, including systemic delivery, intrathecal and/or intraventricular distribution, and polymer implantation, have led to its application in research studies and clinical trials. The authors review the biophysical principles of convective flow and the technology, properties, and clinical applications of convective delivery in the CNS.

Drug delivery to the central nervous system

2021 ◽  
Author(s):  
Elizabeth Nance ◽  
Suzie H. Pun ◽  
Rajiv Saigal ◽  
Drew L. Sellers
Keyword(s):  
Drug Delivery ◽  
Central Nervous System ◽  
Nervous System ◽  
The Central Nervous System
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