scholarly journals Trajectory correction for lunar flyby transfers to libration point orbits using continuous thrust

Astrodynamics ◽  
2021 ◽  
Author(s):  
Yi Qi ◽  
Anton de Ruiter

AbstractTrajectory corrections for lunar flyby transfers to Sun-Earth/Moon libration point orbits (LPOs) with continuous thrusts are investigated using an ephemeris model. The lunar flyby transfer has special geometrical and dynamical structures; therefore, its trajectory correction strategy is considerably different from that of previous studies and should be specifically designed. In this paper, we first propose a control strategy based on the backstepping technique with a dead-band scheme using an ephemeris model. The initial error caused by the launch time error is considered. Since the perturbed transfers significantly diverge from the reference transfers after the spacecraft passes by the Moon, we adopt two sets of control parameters in two portions before and after the lunar flyby, respectively. Subsequently, practical constraints owing to the navigation and propellant systems are introduced in the dynamical model of the trajectory correction. Using a prograde type 2 orbit as an example, numerical simulations show that our control strategy can efficiently address trajectory corrections for lunar flyby transfers with different practical constraints. In addition, we analyze the effects of the navigation intervals and dead-band scheme on trajectory corrections. Finally, trajectory corrections for different lunar flyby transfers are depicted and compared.

2005 ◽  
Vol 56 (7) ◽  
pp. 652-669 ◽  
Author(s):  
Gerard Gómez ◽  
Manuel Marcote ◽  
Josep J. Masdemont

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 312-OR
Author(s):  
AHMAD AL-MRABEH ◽  
SHADEN MELHEM ◽  
SVIATLANA V. ZHYZHNEUSKAYA ◽  
CARL PETERS ◽  
ALISON C. BARNES ◽  
...  

2020 ◽  
Vol 16 (2) ◽  
pp. 148-155 ◽  
Author(s):  
Ashraf Okba ◽  
Salwa Seddik Hosny ◽  
Alyaa Elsherbeny ◽  
Manal Mohsin Kamal

Background and Aims: Women who develop GDM (gestational diabetes mellitus) have a relative insulin secretion deficiency, the severity of which may be predictive for later development of diabetes. This study aimed to investigate the role of fasting plasma glucagon in the prediction of later development of diabetes in pregnant women with GDM. Materials and Methods: The study was conducted on 150 pregnant women with GDM after giving informed oral and written consents and being approved by the research ethical committee according to the declaration of Helsinki. The study was conducted in two phases, first phase during pregnancy and the second one was 6 months post-partum, as we measured fasting plasma glucagon before and after delivery together with fasting and 2 hour post-prandial plasma sugar. Results: Our findings suggested that glucagon levels significantly increased after delivery in the majority 14/25 (56%) of GDM women who developed type 2 DM within 6 months after delivery compared to 6/20 (30%) patients with impaired fasting plasma glucose (IFG) and only 22/105 (20%) non DM women, as the median glucagon levels were 80,76, 55, respectively. Also, there was a high statistical difference between fasting plasma glucagon post-delivery among diabetic and non-diabetic women (p ≤ 0.001). These results indicated the useful role of assessing fasting plasma glucagon before and after delivery in patients with GDM to predict the possibility of type 2 DM. Conclusion: There is a relatively high glucagon level in GDM patients, which is a significant pathogenic factor in the incidence of subsequent diabetes in women with a history of GDM. This could be important in the design of follow-up programs for women with previous GDM.


2004 ◽  
Vol 21 (7) ◽  
pp. 793-797 ◽  
Author(s):  
G. A. Nichols ◽  
J. B. Brown

2014 ◽  
Vol 58 (4) ◽  
pp. 369-376 ◽  
Author(s):  
Joelma Ines Tagliapietra Barros ◽  
Francisco Vagnaldo Fechine ◽  
Renan Magalhães Montenegro Júnior ◽  
Otoni Cardoso do Vale ◽  
Virgínia Oliveira Fernandes ◽  
...  

Objective: To evaluate the effect of sitagliptin on somatosensory-evoked potentials (SEPs) and metabolic control in patients with type 2 diabetes mellitus without clinical diabetic neuropathy. Materials and methods: Interventional, prospective, and open study. Patients with less than six months from the diagnosis were included. Examinations of SEPs and laboratory tests at fasting and after food stimulation were performed before and after three months of treatment with sitagliptin (100 mg/day). Results: There was a reduction in the mean levels of HbA1c (P < 0.0001), fasting glucose (P = 0.001), total cholesterol (P = 0.019), and ALT (P = 0.022). An increase in active GLP-1 was found at the end of the study (P = 0.0025). Several SEPs showed statistically significant differences when analyzed before and after treatment with sitagliptin. Conclusion: The results give a glimpse of the possible use of sitagliptin in the treatment of some neurodegenerative conditions of the peripheral nervous system, in addition to its already established role in glycemic control.


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