Development of Tunable Silk Fibroin/Xanthan Biopolymeric Scaffold for Skin Tissue Engineering Using L929 Fibroblast Cells

2021 ◽  
Vol 18 (1) ◽  
pp. 103-117
Author(s):  
Shailendra Singh Shera ◽  
Rathindra Mohan Banik
2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Witoo Luangbudnark ◽  
Jarupa Viyoch ◽  
Wiroon Laupattarakasem ◽  
Palakorn Surakunprapha ◽  
Pisamai Laupattarakasem

Chitosan/silk fibroin (CS/SF) blend films were prepared and evaluated for feasibility of using the films as biomaterial for skin tissue engineering application. Fourier transform infrared spectroscopy and differential scanning calorimetry analysis indicated chemical interaction between chitosan and fibroin. Chitosan enhancedβ-sheet conformation of fibroin and resulted in shifting of thermal degradation of the films. Flexibility, swelling index, and enzyme degradation were also increased by the chitosan content of the blend films. Biocompatibility of the blend films was determined by cultivation with fibroblast cells. All films showed no cytotoxicity by XTT assay. Fibroblast cells spread on CS/SF films via dendritic extensions, and cell-cell interactions were noted. Cell proliferation on CS/SF films was also demonstrated, and their phenotype was examined by the expression of collagen type I gene. These results showed possibility of using the CS/SF films as a supporting material for further study on skin tissue engineering.


2015 ◽  
Vol 7 (1) ◽  
pp. 53-63 ◽  
Author(s):  
Nandana Bhardwaj ◽  
Wan Ting Sow ◽  
Dipali Devi ◽  
Kee Woei Ng ◽  
Biman B. Mandal ◽  
...  

Development of highly vascular dermal tissue-engineered skin substitutes with appropriate mechanical properties and cellular cues is in need for significant advancement in the field of dermal reconstruction.


2014 ◽  
Vol 55 (4) ◽  
pp. 907-916 ◽  
Author(s):  
Caihong Lei ◽  
Hailin Zhu ◽  
Jingjing Li ◽  
Jiuming Li ◽  
Xinxing Feng ◽  
...  

2017 ◽  
Vol 62 ◽  
pp. 88-95 ◽  
Author(s):  
Xiaolan Zhang ◽  
Chuanlong Jia ◽  
Xiuying Qiao ◽  
Tianyi Liu ◽  
Kang Sun

2019 ◽  
Vol 7 (12) ◽  
pp. 5232-5237 ◽  
Author(s):  
Ying Zhang ◽  
Leihao Lu ◽  
Yuping Chen ◽  
Jie Wang ◽  
Yuyin Chen ◽  
...  

Natural polymer-based wound dressings have gained great attention in skin tissue engineering.


2015 ◽  
Vol 7 (1) ◽  
pp. 142-142 ◽  
Author(s):  
Nandana Bhardwaj ◽  
Wan Ting Sow ◽  
Dipali Devi ◽  
Kee Woei Ng ◽  
Biman B. Mandal ◽  
...  

Correction for ‘Silk fibroin–keratin based 3D scaffolds as a dermal substitute for skin tissue engineering’ by Nandana Bhardwaj et al., Integr. Biol., 2015, DOI: 10.1039/c4ib00208c.


2013 ◽  
Vol 26 (1_suppl) ◽  
pp. 43-49 ◽  
Author(s):  
T. Chlapanidas ◽  
M.C. Tosca ◽  
S. Faragò ◽  
S. Perteghella ◽  
M. Galuzzi ◽  
...  

2020 ◽  
Vol 112 ◽  
pp. 110939 ◽  
Author(s):  
Antonios Keirouz ◽  
Mariia Zakharova ◽  
Jaehoon Kwon ◽  
Colin Robert ◽  
Vasileios Koutsos ◽  
...  

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