Detecting grades of diabetic retinopathy by extraction of retinal lesions using digital fundus images

2021 ◽  
Author(s):  
Anirban Dutta ◽  
Parul Agarwal ◽  
Anushka Mittal ◽  
Shishir Khandelwal
Keyword(s):  
Diabetic Retinopathy ◽  
Fundus Images ◽  
Retinal Lesions

Two-Tier Grading System for NPDR Severities of Diabetic Retinopathy in Retinal Fundus Images

2020 ◽  
Vol 14 ◽  
Author(s):  
Charu Bhardwaj ◽  
Shruti Jain ◽  
Meenakshi Sood
Keyword(s):  
Diabetic Retinopathy ◽  
Statistical Analysis ◽  
Early Stage ◽  
Image Feature ◽  
Grading System ◽  
Fundus Images ◽  
Fundus Image ◽  
Retinal Fundus Images ◽  
Retinal Fundus ◽  
Timely Treatment

: Diabetic Retinopathy is the leading cause of vision impairment and its early stage diagnosis relies on regular monitoring and timely treatment for anomalies exhibiting subtle distinction among different severity grades. The existing Diabetic Retinopathy (DR) detection approaches are subjective, laborious and time consuming which can only be carried out by skilled professionals. All the patents related to DR detection and diagnoses applicable for our research problem were revised by the authors. The major limitation in classification of severities lies in poor discrimination between actual lesions, background noise and other anatomical structures. A robust and computationally efficient Two-Tier DR (2TDR) grading system is proposed in this paper to categorize various DR severities (mild, moderate and severe) present in retinal fundus images. In the proposed 2TDR grading system, input fundus image is subjected to background segmentation and the foreground fundus image is used for anomaly identification followed by GLCM feature extraction forming an image feature set. The novelty of our model lies in the exhaustive statistical analysis of extracted feature set to obtain optimal reduced image feature set employed further for classification. Classification outcomes are obtained for both extracted as well as reduced feature set to validate the significance of statistical analysis in severity classification and grading. For single tier classification stage, the proposed system achieves an overall accuracy of 100% by k- Nearest Neighbour (kNN) and Artificial Neural Network (ANN) classifier. In second tier classification stage an overall accuracy of 95.3% with kNN and 98.0% with ANN is achieved for all stages utilizing optimal reduced feature set. 2TDR system demonstrates overall improvement in classification performance by 2% and 6% for kNN and ANN respectively after feature set reduction, and also outperforms the accuracy obtained by other state of the art methods when applied to the MESSIDOR dataset. This application oriented work aids in accurate DR classification for effective diagnosis and timely treatment of severe retinal ailment.

scholarly journals Deep Learning for Diabetic Retinopathy Detection and Classification Based on Fundus Images: A Review

2021 ◽  
pp. 104599
Author(s):  
Nikos Tsiknakis ◽  
Dimitris Theodoropoulos ◽  
Georgios Manikis ◽  
Emmanouil Ktistakis ◽  
Ourania Boutsora ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Deep Learning ◽  
Fundus Images

scholarly journals Adversarial Attack and Defence through Adversarial Training and Feature Fusion for Diabetic Retinopathy Recognition

Sensors ◽  
2021 ◽  
Vol 21 (11) ◽  
pp. 3922
Author(s):  
Sheeba Lal ◽  
Saeed Ur Rehman ◽  
Jamal Hussain Shah ◽  
Talha Meraj ◽  
Hafiz Tayyab Rauf ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Feature Fusion ◽  
Speckle Noise ◽  
Fundus Images ◽  
Adversarial Examples ◽  
Adversarial Training ◽  
Adversarial Attack ◽  
Retinal Fundus Images ◽  
Attacks And Defenses ◽  
Retinal Fundus

Due to the rapid growth in artificial intelligence (AI) and deep learning (DL) approaches, the security and robustness of the deployed algorithms need to be guaranteed. The security susceptibility of the DL algorithms to adversarial examples has been widely acknowledged. The artificially created examples will lead to different instances negatively identified by the DL models that are humanly considered benign. Practical application in actual physical scenarios with adversarial threats shows their features. Thus, adversarial attacks and defense, including machine learning and its reliability, have drawn growing interest and, in recent years, has been a hot topic of research. We introduce a framework that provides a defensive model against the adversarial speckle-noise attack, the adversarial training, and a feature fusion strategy, which preserves the classification with correct labelling. We evaluate and analyze the adversarial attacks and defenses on the retinal fundus images for the Diabetic Retinopathy recognition problem, which is considered a state-of-the-art endeavor. Results obtained on the retinal fundus images, which are prone to adversarial attacks, are 99% accurate and prove that the proposed defensive model is robust.

An Explainable Deep Learning Ensemble Model for Robust Diagnosis of Diabetic Retinopathy Grading

2021 ◽  
Vol 17 (3s) ◽  
pp. 1-24
Author(s):  
Mohammad Shorfuzzaman ◽  
M. Shamim Hossain ◽  
Abdulmotaleb El Saddik
Keyword(s):  
Diabetic Retinopathy ◽  
Deep Learning ◽  
Vision Loss ◽  
Final Diagnosis ◽  
Learning Rate ◽  
Ensemble Model ◽  
Fundus Images ◽  
Robust Detection ◽  
Retinal Fundus Images ◽  
Retinal Fundus

Diabetic retinopathy (DR) is one of the most common causes of vision loss in people who have diabetes for a prolonged period. Convolutional neural networks (CNNs) have become increasingly popular for computer-aided DR diagnosis using retinal fundus images. While these CNNs are highly reliable, their lack of sufficient explainability prevents them from being widely used in medical practice. In this article, we propose a novel explainable deep learning ensemble model where weights from different models are fused into a single model to extract salient features from various retinal lesions found on fundus images. The extracted features are then fed to a custom classifier for the final diagnosis of DR severity level. The model is trained on an APTOS dataset containing retinal fundus images of various DR grades using a cyclical learning rates strategy with an automatic learning rate finder for decaying the learning rate to improve model accuracy. We develop an explainability approach by leveraging gradient-weighted class activation mapping and shapely adaptive explanations to highlight the areas of fundus images that are most indicative of different DR stages. This allows ophthalmologists to view our model's decision in a way that they can understand. Evaluation results using three different datasets (APTOS, MESSIDOR, IDRiD) show the effectiveness of our model, achieving superior classification rates with a high degree of precision (0.970), sensitivity (0.980), and AUC (0.978). We believe that the proposed model, which jointly offers state-of-the-art diagnosis performance and explainability, will address the black-box nature of deep CNN models in robust detection of DR grading.

Diabetic Retinopathy Detection and Classification from Fundus Images Using Deep Learning

2021 ◽  
Author(s):  
Pratiksha Shetgaonkar ◽  
Shailendra Aswale ◽  
Saurabh Naik ◽  
Amey Gaonkar ◽  
Swapnil Gawade ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Deep Learning ◽  
Fundus Images

scholarly journals Automatic detection of diabetic retinopathy and its progression in sequential fundus images of patients with diabetes

2018 ◽  
Vol 97 (4) ◽  
pp. e667-e669
Author(s):  
Alexander Dietzel ◽  
Carolin Schanner ◽  
Aura Falck ◽  
Nina Hautala
Keyword(s):  
Diabetic Retinopathy ◽  
Automatic Detection ◽  
Fundus Images ◽  
Patients With Diabetes

scholarly journals Modified Curvature-based Trigonometric Identities for Retinal Blood Vessel Tortuosity Measurement in Diabetic Retinopathy Fundus Images

2018 ◽  
Vol 7 (4.11) ◽  
pp. 133
Author(s):  
N. Badariah A. Mustafa ◽  
W. Mimi Diyana W. Zaki ◽  
Aini Hussain ◽  
Jemaima Che Hamzah
Keyword(s):  
Diabetic Retinopathy ◽  
Blood Vessel ◽  
False Negative ◽  
False Negative Rate ◽  
Fundus Images ◽  
Current Clinical Practice ◽  
Clinical Experiences ◽  
Retinal Blood Vessel ◽  
Specific Standard ◽  
Vessel Curvature

In current clinical practice, there is no specific standard and grading system that can be used to measure the behaviour of the retinal blood vessel curvature. The retinal blood vessel curvature is measured based on clinical experiences. It is very subjective and inconsistent to describe the presence of tortuosity in fundus images. Thus, this paper aims to measure the tortuosity of retinal blood vessel using curvature-based method and investigate its relationship with diabetic retinopathy (DR) disease. The proposed tortuosity measures have been tested on 43 fundus images belonging to patients who have been diagnosed with DR disease and validated by two clinical experts from our collaborative hospital. On average, the proposed algorithm achieved 90.7% (accuracy), 98.72% (sensitivity) and 9.3% (false negative rate), that shows significant tortuosity presence in diabetic retinopathy fundus images. 

scholarly journals ANN and SVM to recognize Texture features for spontaneous Detection and Rating of Diabetic Retinopathy

2019 ◽  
Vol 9 (1) ◽  
pp. 5590-5595
Keyword(s):  
Diabetic Retinopathy ◽  
Research Work ◽  
Texture Features ◽  
Support Vector ◽  
Fundus Images ◽  
Small Vessels ◽  
The Neural Network ◽  
Major Loss ◽  
Occurrence Matrix ◽  
Fluid Leak

The higher levels of blood glucose most often causes a metabolic disorder commonly called as Diabetes, scientifically as Diabetes Mellitus. A consequence of this is a major loss of vision and in long terms may eventually cause complete blindness. It initiates with swelling on blood vessels, formation of microaneurysms at the end of narrow capillaries. Haemorrhages due to rupture of small vessels and fluid leak causes exudates. The specialist examines it to diagnose and gives proper treatment. Fundus images are the fundamental tool for proper diagnosis of patients by medical experts. In this research work the fundus images are taken for processing, the neural network and support vector machine are trained for the proposed model. The features are extracted from the diabetic retinopathy image by using texture based algorithms such as Gabor, Local binary pattern and Gray level co-occurrence matrix for rating the level of diabetic retinopathy. The performance of all methods is calculated based on accuracy, precision, Recall and f-measure.

Sign in / Sign up

Export Citation Format

Share Document