Tamoxifen and hydroxytamoxifen as intramembraneous inhibitors of lipid peroxidation. Evidence for peroxyl radical scavenging activity

1994 ◽  
Vol 47 (11) ◽  
pp. 1989-1998 ◽  
Author(s):  
JoséB.A. Custódio ◽  
Teresa C.P. Dinis ◽  
Leonor M. Almeida ◽  
Vítor M.C. Madeira
Keyword(s):  
Lipid Peroxidation ◽  
Peroxyl Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity

Anti-hemolytic and Peroxyl Radical Scavenging Activity of Organoselenium Compounds: An In Vitro Study

2010 ◽  
Vol 140 (2) ◽  
pp. 127-138 ◽  
Author(s):  
B. Santhosh Kumar ◽  
Amit Kunwar ◽  
Beena G. Singh ◽  
Adeel Ahmad ◽  
K. Indira Priyadarsini
Keyword(s):  
Peroxyl Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
In Vitro Study ◽  
Vitro Study ◽  
Scavenging Activity ◽  
Organoselenium Compounds

scholarly journals CHEMICAL COMPOSITION AND HEPATOPROTECTIVE EFFECTS OF POLYPHENOLIC FRACTION FROM RIVEA HYPOCRATERIFORMIS IN PARACETAMOL INDUCED LIVER DAMAGE IN WISTAR ALBINO RATS

2016 ◽  
Vol 8 (10) ◽  
pp. 228
Author(s):  
Shivakumar S. Godipurge ◽  
Naveen J. Biradar ◽  
Jaiprakash S. Biradar ◽  
Nitin Mahurkar
Keyword(s):  
Lipid Peroxidation ◽  
Chemical Composition ◽  
Hydroxyl Radical ◽  
Liver Damage ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Aerial Parts ◽  
Hepatoprotective Effects ◽  
Phenolic And Flavonoid

<p><strong>Objective: </strong>This study was designed to chemical composition and hepatoprotective effects of a polyphenolic fraction of aerial parts of <em>R. hypocrateriformis </em>(PPFRH). It was shown to exhibit strong <em>in vitro</em> lipid peroxidation and scavenging activity against hydroxyl radical.</p><p><strong>Methods: </strong>The chemical composition of a polyphenolic fraction of <em>R. hypocrateriformis</em> was analyzed by High-performance liquid chromatography method. Hepatocellular injuries induced by paracetamol were assessed by liver damage in Wistar albino rat; the hepatoprotective effect was evaluated by biochemical parameters in rat serum, antioxidant hydroxyl radical scavenging activity and lipid peroxidation in liver tissue.</p><p><strong>Results: </strong>The polyphenolic fraction of aerial parts of <em>R. hypocrateriformis</em> for lipid peroxidation is significantly (p&lt;0.05). In the hepatoprotective activity of liver enzymes and hepatic necrosis were significantly (p&lt;0.001) closer to paracetamol. The correlation coefficient between the hydroxyl scavenging radical and total phenolic and flavonoid contents were found to be R² = 0.9045 and R² = 0.8876 suggesting the contribution of phenolic and flavonoid compounds of the polyphenolic fraction of aerial parts of <em>R. hypocrateriformis</em> by 90% and 88% to its radical scavenging activity.</p><p><strong>Conclusion: </strong>The polyphenolic fraction of aerial parts of <em>R. hypocrateriformis</em> possesses a significant protective effect against acute hepatotoxicity induced by paracetamol and which may be due to the phenolic and flavonoid components.</p>

Comparison of antioxidant activities of onion and garlic extracts by inhibition of lipid peroxidation and radical scavenging activity

2003 ◽  
Vol 81 (4) ◽  
pp. 485-493 ◽  
Author(s):  
Anna Maria Nuutila ◽  
Riitta Puupponen-Pimiä ◽  
Marjukka Aarni ◽  
Kirsi-Marja Oksman-Caldentey
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity

Peroxyl radical scavenging activity of Ginkgo biloba extract EGb 761

1995 ◽  
Vol 49 (11) ◽  
pp. 1649-1655 ◽  
Author(s):  
Indrani Maitra ◽  
Lucia Marcocci ◽  
Marie Therese Droy-Lefaix ◽  
Lester Packer
Keyword(s):  
Ginkgo Biloba ◽  
Peroxyl Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Ginkgo Biloba Extract ◽  
Scavenging Activity ◽  
Egb 761

scholarly journals Free Radical Scavenging Activity, Reducing Power and Anti-Hemolytic Capacity of Algerian Drimia maritima Baker Flower Extracts

2020 ◽  
Vol 10 (4) ◽  
pp. 70-78
Author(s):  
Abir Rezzagui ◽  
Abderrahmane Senator ◽  
Soumia Benbrinis ◽  
Hamama Bouriche
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Phenolic Compounds ◽  
Superoxide Anion ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Free Radical Scavenging ◽  
Scavenging Activity

This study was undertaken to evaluate the antioxidant and anti-hemolytic properties of Algerian Drimia maritima Baker flower extracts. Determination of phenolic content was carried out to estimate the chemical composition of D. maritima extracts. Antioxidant properties were investigated in all extracts using free radical scavenging activity (against DPPH, ABTS, hydroxyl radical, and superoxide anion), reducing power, inhibition of lipid peroxidation, and anti-hemolytic capacity. Phenolic determination revealed that D. maritima flowers contain phenolic compounds, flavonoids, and tannins. Ethyl acetate extract showed the highest reducing power and scavenging activity using DPPH and ABTS assays. However, aqueous extract was the most effective against hydroxyl radical, superoxide anion, and lipid peroxidation. The half-time of hemolysis indicates that chloroform extract exhibited the best anti-hemolytic capacity in the AAPH induced hemolysis model. The results of this study suggest that D. maritima could be used as a possible source of antioxidant phenolic compounds and that further determination of these compounds may provide more information on their medicinal value.  Keywords: Drimia maritima, phenolic compounds, scavenging activity, reducing power, anti-hemolytic.

scholarly journals Peroxyl Radical-Scavenging Activity of Plasma Determined by Electron Paramagnetic Resonance.

1999 ◽  
Vol 27 (2) ◽  
pp. 103-112 ◽  
Author(s):  
Takaaki FUJII ◽  
Toshikazu YOSHIKAWA ◽  
Yuji NAITO ◽  
Toru TANIGAWA ◽  
Motoharu KONDO ◽  
...  
Keyword(s):  
Electron Paramagnetic Resonance ◽  
Peroxyl Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Scavenging Activity ◽  
Paramagnetic Resonance ◽  
Electron Paramagnetic
Sign in / Sign up

Export Citation Format

Share Document