Lymphotoxin-induced changes in target-cell plasma-membrane protein: Enhancement of synthesis and content

1982 ◽  
Vol 67 (1) ◽  
pp. 14-22 ◽  
Author(s):  
Werner Rosenau ◽  
Gertrude Burke
1989 ◽  
Vol 264 (33) ◽  
pp. 19974-19978 ◽  
Author(s):  
A Galvan ◽  
P D Lampe ◽  
K C Hur ◽  
J B Howard ◽  
E D Eccleston ◽  
...  

1987 ◽  
Vol 241 (3) ◽  
pp. 801-807 ◽  
Author(s):  
R T Earl ◽  
E E Billett ◽  
I M Hunneyball ◽  
R J Mayer

Reconstituted Sendai-viral envelopes (RSVE) were produced by the method of Vainstein, Hershkovitz, Israel & Loyter [(1984) Biochim. Biophys. Acta 773, 181-188]. RSVE are fusogenic unilamellar vesicles containing two transmembrane glycoproteins: the HN (haemagglutinin-neuraminidase) protein and the F (fusion) factor. The fate of the viral proteins after fusion-mediated transplantation of RSVE into hepatoma (HTC) cell plasma membranes was studied to probe plasma-membrane protein degradation. Both protein species are degraded at similar, relatively slow, rates (t1/2 = 67 h) in HTC cells fused with RSVE in suspension. Even slower degradation rates for HN and F proteins (t1/2 = 93 h) were measured when RSVE were fused with HTC cells in monolayer. Lysosomal degradation of the transplanted viral proteins is strongly implicated by the finding that degradation of HN and F proteins is sensitive to inhibition by 10 mM-NH4Cl (81%) and by 50 micrograms of leupeptin/ml (70%).


2004 ◽  
Vol 54 (4) ◽  
pp. 887-904 ◽  
Author(s):  
Robert J. Cain ◽  
Richard D. Hayward ◽  
Vassilis Koronakis

2015 ◽  
Vol 7 (17) ◽  
pp. 7076-7094 ◽  
Author(s):  
Chih-Yun Hsia ◽  
Mark J. Richards ◽  
Susan Daniel

Lipid–protein interactions are essential for modulating membrane protein structures and biological functions in the cell plasma membrane. In this review we describe the salient features of classical and emerging methodologies for studying protein–lipid interactions and their limitations.


Blood ◽  
2013 ◽  
Vol 121 (14) ◽  
pp. 2659-2668 ◽  
Author(s):  
Jamie A. Lopez ◽  
Olivia Susanto ◽  
Misty R. Jenkins ◽  
Natalya Lukoyanova ◽  
Vivien R. Sutton ◽  
...  

Key Points Granzymes diffuse through perforin pores on the target cell plasma membrane.


Langmuir ◽  
2016 ◽  
Vol 32 (12) ◽  
pp. 2963-2974 ◽  
Author(s):  
Mark J. Richards ◽  
Chih-Yun Hsia ◽  
Rohit R. Singh ◽  
Huma Haider ◽  
Julia Kumpf ◽  
...  

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