Potentiometric acid-base titrations in molten salts—V. A comparative study on the acid character of some of group 1 and group 2 cations

Purpose. To compare the capsule edges ultrastructure obtained by two femtosecond laser-assisted cataract surgery (FLACS) platforms and manual continuous curvilinear capsulorhexis (CCC) using scanning electron microscopy (SEM). Setting. Eye Clinic, University of Trieste, Italy. Design. Experimental comparative study. Methods. 150 anterior capsules were collected and divided into three groups as follows: Group 1 (50 capsules) obtained with manual CCC, Groups 2 and 3 (each with 50 capsules) obtained with the Catalys Laser and the LenSx Laser, respectively. All samples were imaged by means of SEM and regularity of the cut surface, and thickness of the capsule edge were evaluated and compared. Results. All femtosecond laser (FSL) capsules were perfectly circular, whereas some alteration of the circular shape was observed in the manual ones. Group 1 showed a smooth and regular capsule edge without any surface irregularity, conversely Groups 2 and 3 showed postage-stamp perforations on the capsule edge. The cut surface irregularity value in Group 2 was 1.4 ± 0.63, while it was 0.7 ± 0.49 in Group 3 (p<0.05). Group 1 had a significantly lower thickness of the capsule edge than the FSL groups (p<0.05). No statistically significant difference in the capsule edge thickness between the FSL groups was found (p=0.244). Conclusions. Despite the presence of slight cut surface irregularities, both FSL capsulotomies showed a better geometry and circularity than the manual ones. Capsulotomy specimens obtained using both FSL capsulotomies showed laser-induced alterations of the capsule edge when compared with smooth and regular edges obtained using manual CCC.

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Reduction of the Risk of Relapse of Symptoms When Using Esophagoprotector in Patients Requiring Temporary Cancellation of Antisecretory Therapy

Effective Pharmacotherapy ◽

10.33978/2307-3586-2021-17-16-26-30 ◽

2021 ◽

Vol 17 (16) ◽

pp. 26-30

Author(s):

Yu.A. Kucheryavy ◽

◽

P.R. Movtaeva ◽

D.N. Andreev ◽

R.I. Shaburov ◽

...

Keyword(s):

Comparative Study ◽

Underlying Disease ◽

On Demand ◽

Long Time ◽

Prospective Comparative Study ◽

Group 2 ◽

Significant Regression ◽

Risk Of Relapse ◽

Group 1

Objective: to evaluate the effectiveness of an esophagoprotector in reducing the risk of recurrent symptoms of gastroesophageal reflux disease (GERD) in patients who requiring temporary cancellation of therapy with proton pump inhibitors (PPIs). Material and methods. For the prospective comparative study there were selectively chose patients who had been taking PPIs for a long time (at least one month) for the underlying disease and who required temporary discontinuation of antisecretory therapy due to objective medical reasons. The study included patients with endoscopically and/or pH-metrically verified GERD, as well as histologically verified Barrett's esophagus. In the process of randomization of patients, two equal groups were formed, depending on the therapy received at the time of PPI withdrawal: group 1 received antacids on demand, group 2 received antacids on demand, as well as the esophagoprotector Alfasoxx at a dose of 10 ml four times a day (after each meal and at night). The follow-up period was two weeks. The patients recorded episodes of heartburn in their personal diaries. Results. The study included 60 patients (28 men and 32 women). The average age of the examined patients was 43.1 ± 5.3 years. By the end of the two-week follow-up period, the frequency of recurrent symptoms in group 1 was 36.7%, while in group 2 it was 13.3%. The use of the esophagoprotector Alfasoxx contributed to the significant regression of the risk of heartburn recurrence (odds ratio 0.2657; 95% confidence interval (CI) 0.07328-0.9637; p = 0.0438) in comparison with the group of patients who received only antacids in the on-demand mode. When analyzing the population of patients who had relapsed symptoms, it was demonstrated that the average number of heartburn episodes in group 1 was 6.18 (95% CI 4,1930-8,1706), and in group 2 – 4.50 (95% CI 0,7121-8,2879). Conclusion. This prospective comparative study demonstrated that the use of the esophagoprotector Alfasoxx helps to reduce the risk of relapse of GERD symptoms in patients requiring temporary cancellation of PPI therapy.

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A COMPARATIVE STUDY TO EVALUATE THE OUTCOME OF PONSETI'S TECHNIQUE AND ACCELERATED PONSETI'S TECHNIQUE FOR CORRECTION OF CLUBFOOT

10.36106/ijar/2802068 ◽

2021 ◽

pp. 59-61

Author(s):

Ashok Vidhyarthi ◽

H.S. Varma ◽

Rajeev Singh ◽

Rajendra Thakur ◽

Darwin Kumar Thakur

Keyword(s):

Comparative Study ◽

Ponseti Method ◽

Congenital Deformity ◽

Duration Of Treatment ◽

Protocol Group ◽

Pirani Score ◽

Prospective Comparative Study ◽

Group 2 ◽

Accelerated Ponseti ◽

Group 1

Introduction: Clubfoot is a common congenital deformity with incidence of1-6.8/1000 live births. Ponseti method is currently the gold standard for treatment of clubfoot which conventionally involves weekly plaster changes. A prospective comparative study was carried out at our hospital where we compared one group with weekly plaster change to other group with twice weekly plaster change, using the classical Ponseti protocol of manipulation. A total 50 feet (36 children ), divided into two Methods: groups, were randomly allocated to either Group 1 – 25 feet(accelerated Ponseti) or Group 2 – 25 feet (standard Ponseti). Group 2 underwent serial manipulations and casting once a week and Group 1 received manipulations and castings twice a week. Pirani score was documented at the time of presentation, after each cast, and at the time of removalof nal cast to assess the success of treatment ( Pirani score ≤1). A tota Results: l 43 feet (29 patients) underwent the entire course of treatment, while 7 patients discontinued the treatment during the course of the study. 14 patients, i.e, 21 feet were treated with Accelerated Ponseti Protocol (APP),i.e Group -1, and 15 patients, i.e, 22 feet were treated with Standard Ponseti Protocol (SPP), i.e Group-2. Mean duration of treatment from the rst cast to tenotomy in the accelerated ponseti protocol group was 20.57 ± 4.5 days (ranging from 12 to 29 days), and in standard ponseti protocol group was 39.66 ± 6.9 days (ranging from 29 to 51 days). Conclusion: Both the methods proved to be equally efcacious for the management of clubfoot in our study. However, the accelerated method had an overall shorter treatment duration making it convenient for the parents. As the patient is under direct observation of surgeons, complications, in any, are detected early and easily. Overall, the accelerated technique is more practical, benecial, and equally efcacious as standard ponseti technique, providing a more rapid correction of the deformity.

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Topical Nitroglycerine Versus Lateral Sphincterectomy for Fissure in Ano: A Hospital Based Comparative Study

Journal of Nepalgunj Medical College ◽

10.3126/jngmc.v16i2.24875 ◽

2018 ◽

Vol 16 (2) ◽

pp. 40-43

Author(s):

Bimarsh Adhikari ◽

Sunil Kumar Yadav ◽

S. N. Gupta

Keyword(s):

Comparative Study ◽

College Teaching ◽

Pain Reduction ◽

Lateral Sphincterotomy ◽

Female Ratio ◽

Benign Condition ◽

Number Of Patients ◽

The Mean ◽

Group 2 ◽

Group 1

Background: Anal fissure is a common benign condition presenting as severe pain, constipations and bleeding per rectum. It is defined as longitudinal tear or defect in anal canal skin. Surgical treatment of this conditions requires hospital admission and complications, like bleeding, infection and to its severe extent continence disturbances. That warrants a new treatment modality as pharmacological sphincterotomy i. e topical GTN (glycerine trinitrate) whose effects are reversible, cost effective and simple. Objective: The objective is to compare the effectiveness of topical GTN over lateral sphincterotomy in terms of pain management and healing of fissure. Method: This was a comparative study carried out in the department of Surgery at Nepalgunj Medical College, Teaching Hospital. Two groups were created and 25 patients in each group were put randomly. First group (Group 1) used topical GTN whereas second group(Group 2) underwent lateral sphincterotomy for treatment of fissure. The two groups were reassessed at 4 and 8 weeks for pain and fissure healing. Result: Total number of patients was 50. Each group consisted of 25 patients. The male to female ratio in group 1 was 1:1.5 and in group 2 it was 1: 1.8. In group 1 patients after 4 weeks of application of GTN pain reduced from the mean of 80±15 at the time of presentation to 50±9.27. When these patients were seen after 8 weeks, the pain reduction on VAS was nil in 21 patients out of 25. In group 2 the mean score fell from 75±15 to 20±10 after 4 weeks and at 8weeks 23 out of 25 patients didn't have any pain. It was observed that the pain reduction and healing were faster in group 2 patients when evaluated after 4 weeks (p=0.0029). but at the end of 8 weeks both group patients were similar in terms of pain reduction and healing of fissure (p=.28). Conclusion: According to study local GTN application is as effective as lateral sphincterotomy with cost effectiveness, simple with tolerable side effect and no continence disturbances.

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Comparative study of laparoscopic hernia repair versus open hernia repair

Journal of Nobel Medical College ◽

10.3126/jonmc.v7i2.22303 ◽

2018 ◽

Vol 7 (2) ◽

pp. 30-34

Author(s):

Rohit Prasad Yadav ◽

Dipendra Thakur ◽

Bashu Dev Baskota ◽

Amit Kumar Shah ◽

Kaushal Samsher Thapa ◽

...

Keyword(s):

Hernia Repair ◽

Comparative Study ◽

Hospital Stay ◽

Laparoscopic Hernia Repair ◽

Fatty Tissue ◽

Duration Of Surgery ◽

Group 2 ◽

Lower Pain Score ◽

Open Hernia Repair ◽

Group 1

Background: Hernia is the abnormal exit of an organ or fatty tissue, such as the bowel, through the weak wall of the cavity in which it normally resides. Repair of inguinal hernia is common surgical procedures. This study aims to compare between laparoscopic and open hernia repair. Method: Study is non randomized comparative study. Study includes 76 patients who had undergone surgery for hernioplasty. Among them 38 undergone laparoscopic hernioplasty and 38 undergone open hernioplasty from June 2016 to August 2018. Results: Mean hospital stay was 2.95 days in group 1 and 4.03 in group 2 .VAS was found to be 2.45 in group 1 and 5.71 in group 2 which is significantly low in group 1 patients with p<0.001. Duration of surgery is more in group 1 with mean duration of 94.08 minutes comparing to group 2 with mean duration of 43.55 minutes (with p<0.001). Conclusion: Laparoscopic hernia repair offers advantages over open repair in terms of less hospital stay and lower pain score for patient not contraindicated for general anesthesia and complicated hernia.

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Comparative study of pharmacological and combined pharmaco-mechanical method of induction of labour: a randomised study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20211523 ◽

2021 ◽

Vol 10 (5) ◽

pp. 1977

Author(s):

Anshu Kumari ◽

Mahantappa A. Chiniwar ◽

Sharada B. Menasinkai

Keyword(s):

Comparative Study ◽

Active Phase ◽

Induction Of Labour ◽

Research Centre ◽

Cervical Canal ◽

Mechanical Method ◽

Randomised Study ◽

Group 2 ◽

Foley’S Catheter ◽

Group 1

Background: Comparative study of Pharmacological and Pharmaco- Mechanical method of induction of labour- A Randomised study. The objective of the study was to compare efficacy of pharmacological and combined pharmaco-mechanical method of induction of labour.Methods: A study was conducted in the department of Obstetrics and gynaecology, Adichunchanagiri Institute of Medical Sciences and Research Centre for a period of 18 months. 200 pregnant women requiring induction of labour were included in the study. In group 1 Dinoprostone 0.5 mg gel was inserted into cervical canal. In group 2 Foley’s catheter No 18 F was inserted within the cervix. The balloon of the catheter was filled with 30 ml normal saline and at the same time Dinoprostone 0.5 mg gel was inserted into posterior vaginal fornix. The Excel and SPSS (SPSS Inc, Chicago V 18.5) software packages were used for data entry and analysis. The results were averaged (mean ± Std Deviation) for each parameter for continuous data in tables.Results: Mean induction to active phase interval in group 1 was 8.43±4.11 hrs, in group 26.82±3.01 hrs (p =0.001). The rate of vaginal delivery in group 1 and group 2 was 55% and 66% respectively, difference was statistically significant (p=0.026).Conclusions: Synchronous use of intracervical Foley’s catheter and Dinoprostone 0.5 mg resulted in a shorter time for progress to active phase and also shortened induction to delivery interval as compared to Dinoprostone 0.5 mg alone. Higher risk of caesarean delivery was associated with single method as compared to combined methods.

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Unilateral Versus Bilateral Frontalis Suspension Sling Surgery for Correction of Severe Unilateral Congenital Ptosis.

Asian Journal of Medical Research ◽

10.47009/ajmr.2020.9.1.ot2 ◽

2020 ◽

Vol 9 (1) ◽

pp. OT05-OT08

Author(s):

Jyoti Dhaka ◽

Ashok Kumar Grover

Keyword(s):

Comparative Study ◽

Surgical Outcome ◽

Fascia Lata ◽

P Value ◽

Congenital Ptosis ◽

Sling Surgery ◽

Frontalis Suspension ◽

Cosmetic Outcomes ◽

Group 2 ◽

Group 1

Background: To compare the surgical outcome of unilateral silicone sling with bilateral fascia latafrontalis suspension surgery for severe unilateral congenital ptosis.Subjects and Methods:This prospective, interventional and comparative study examined 30 patients of severe unilateral congenital ptosis. 30 patients were divided in to 2 groups, group 1 included 15 patients who underwent unilateral silicone sling frontalis suspension surgery and group 2 included 15 patients who underwent contralateral levator excision with bilateral fascia latafrontalis sling surgery.Results:Mean improvement in MRD1 after surgery in group 1 who underwent unilateral silicone sling surgery was 3.9+1.18 mm and in group 2 who underwent bilateral fascia lata it was 4.9+0.89 mm (p value 0.0001). Excellent results (difference of lid height <1 mm) were seen in 93.3% patients who underwent bilateral fascia latafrontalis sling while in 73.3% patients of unilateral silicone sling. All patients who underwent bilateral fascia lata showed excellent lid crease (symmetric without obliteration) and 80% of the patients who underwent unilateral silicone sling surgery (p value 0.032).Conclusion: Functional and cosmetic outcomes regarding MRD1, symmetry of lid height, lid crease were noted better in group 2 patients who underwent contralateral levator excision with bilateral fascia latafrontalis suspension surgery as compared to group 1 patients who underwent unilateral silicone sling surgery.

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Comparative study between open and laparoscopic lymphadenectomy (pelvic and para-aortic) in gynecological malignancies

International Surgery Journal ◽

10.18203/2349-2902.isj20181583 ◽

2018 ◽

Vol 5 (5) ◽

pp. 1657

Author(s):

Hytham R. Yassin ◽

Soliman ALShakhs ◽

Mohammed Hamed ◽

Adel Karam ◽

Mohammed Mouneer

Keyword(s):

Comparative Study ◽

Radical Surgery ◽

Safe Procedure ◽

Gynecological Malignancies ◽

Number Of Patients ◽

Significant Difference ◽

Operative Complications ◽

Group 2 ◽

Group 1

Background: Objective of present study was to compare the results of lymphaenectomy (pelvic and para-aortic) between laparoscopy and laparotomy in gynecological malignancies.Methods: Authors analyze the results of 30 patients suffering from gynecological malignancies (Enometrial, Ovarian and cervical) submitted to surgery as apart of treatment. Patients were classified in Two Groups Group (1) included15 patients were submitted to open radical surgery and group (2) included 15 patients Were submitted to laparoscopic radical surgery between May 2016 and October 2017.Results: In present comparative study, there was significant difference regarding intra operative blood loss, operative time and post operative hospital stay (P<0.001) and there was no significant difference regarding intra-operative complications, post-operative complications, total number of lymph node harvested, number of positive lymphnodes (P>0.05).Conclusions: Laparoscopic lymphadenectomy is a technically feasible and safe procedure. Authors recommend further study in large number of patients with longer duration and follow up period for assessment of oncological out-come.

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Comparative study of the effectiveness and residual effect of preoperative antisepsis with 4% chlorhexidine gluconate associated with 70% ethyl alcohol and 0.5% alcoholic chlorhexidine gluconate in dogs

Acta Veterinaria Brasilica ◽

10.21708/avb.2021.15.2.9801 ◽

2021 ◽

Vol 15 (2) ◽

pp. 161-165

Author(s):

Joseneia Boeing ◽

Amanda Marcondes Pires ◽

Danielli Aparecida Lavelli ◽

Gabriel Godoi de Moraes ◽

Paola Castro Moraes ◽

...

Keyword(s):

Comparative Study ◽

Ethyl Alcohol ◽

Bacterial Growth ◽

Residual Effect ◽

Chlorhexidine Gluconate ◽

Alcohol Group ◽

Skin Bacteria ◽

Colony Forming Units ◽

Group 2 ◽

Group 1

The effectiveness of antisepsis of surgical sites in 20 animals (canine species) was compared and subdivided into two groups, using 4% chlorhexidine gluconate associated with alcohol (group 1) and 0.5% chlorhexidine gluconate (group 2). The samples were collected through skin swab after trichotomy (T1), after definitive antisepsis (T2) and one hour after the use of antiseptic (T3), and then submitted to the count of colony forming units (CFU). In both groups, bacterial growth occurred in T1; in T2, the reduction of CFUs was significant for both groups (G1 and G2); however, if we consider absolute values, we can see in T1 a greater amount of CFUs in G2, and when evaluating the results of T2, we can see values which are very similar between G1 and G2, which may suggest greater efficiency of G2 in initial times after antisepsis. In T3, the reduction of CFUs was more effective for G1, suggesting a greater residual effect when compared to G2. Both antiseptic protocols were effective as they significantly reduced the number of skin bacteria, both in T2 and T3.

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A retrospective comparative study to evaluate the efficacy and safety of mifepristone with misoprostol over misoprostol alone in induction in labor

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20184981 ◽

2018 ◽

Vol 7 (12) ◽

pp. 5140

Author(s):

Reena Sharma ◽

B. R. Sharma ◽

Poojan Dogra

Keyword(s):

Comparative Study ◽

Induction Of Labour ◽

Cervical Ripening ◽

Efficacy And Safety ◽

Group A ◽

The Mean ◽

Group 2 ◽

Group B ◽

Retrospective Comparative Study ◽

Group 1

Background: The aim is to compare the improvement in pre-induction Bishop’s score, proportion of patients going in labor and induction–delivery interval after using the Misoprostol versus Mifepristone and Misoprostol as cervical ripening and labor inducing agent.Methods: It is retrospective comparative study conducted on 110 women. Women were randomized in group A and in group B of 55 patients in each group. Group A received tab Mifepristone 200 mg orally on day 1 followed by Misoprostol 25 ug after 48 hours and continued 6 hourly till maximum four tablets and group B patients received tablet Misoprostol 25ug and continued 25ug 6hrly maximum 4 doses. Women observed for improvement in Bishop‟s score, induction-delivery interval and requirement of subsequent doses of Misoprostol.Results: Present study concluded that tablet Mifepristone is an efficient cervical ripening and inducing agent of labor as pre-induction Bishop’s score was improved. 36.4%patients went into labor only with tablet Mifepristone. The mean induction-delivery interval was,19±12.2hrs in Group 1 as compare to 13.1±13.0 hrs in Group 2. Mean Bishop’s score observed in Group 1 were 2.5±1.78 and 1.67±1.25 in Group 2. It was observed that there was significant improvement in the Bishop’s score after giving Mifepristone to the patients; mean Bishop’s 24hrs after mifepristone were 4.03±1.80. Repeated dose of Misoprostol required in Group 1 was observed to be higher than group 2 as shown in table 8. Mean misoprostol doses required in group 1 was 2.56±1.15 as compared to 1.71±1.58 in group 2.Conclusions: Mifepristone with Misoprostol reduce the induction delivery interval and more potent in combination for induction of labour as compared to Misoprostol alone.

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