Effects of flunarizine on postischemic blood flow, energy metabolism and neuronal damage in the rat brain

1988 ◽  
Vol 158 (3) ◽  
pp. 271-274 ◽  
Author(s):  
Thomas Beck ◽  
Jörg Nuglisch ◽  
Dirk Sauer ◽  
Gerhard Wilhelm Bielenberg ◽  
Hans Dieter Mennel ◽  
...  
2004 ◽  
Vol 24 (2) ◽  
pp. 188-190 ◽  
Author(s):  
Rie Hosoi ◽  
Maki Okada ◽  
Jun Hatazawa ◽  
Antony Gee ◽  
Osamu Inoue

Fluorocitrate, a selective astrocytic toxin, was microinjected into the right striatum of rat brain, and the regional distribution of 14C-acetate was measured using autoradiography. A significant reduction (more than 80%) in 14C-acetate uptake over a 5-minute period was observed in the right striatum, compared with that in the left striatum (saline infused), 4 hours after fluorocitrate (1 nmol/μL) infusion. This effect was transient, and 14C-acetate uptake had almost returned to normal at 24 hours after the fluorocitrate infusion. In contrast, the regional blood flow in the striatum, as determined using 14C-iodoamphetamine, was significantly increased by the fluorocitrate infusion. The present observations indicate that 14C-acetate uptake might be a useful characteristic for examining astrocytic energy metabolism in the intact brain.


1994 ◽  
Vol 86 (4) ◽  
pp. 287-293 ◽  
Author(s):  
M. Dellian ◽  
S. Walenta ◽  
F. Gamarra ◽  
G. E. H. Kuhnle ◽  
W. Mueller-Klieser ◽  
...  

2004 ◽  
Vol 339-339 (1-2) ◽  
pp. 230-235 ◽  
Author(s):  
Gerhard Wilhelm Bielenberg ◽  
Dir Sauer ◽  
J�rg Nughsch ◽  
Thomas Beck ◽  
Christine Ro�berg ◽  
...  
Keyword(s):  

2001 ◽  
Vol 13 (1) ◽  
pp. 119-128 ◽  
Author(s):  
Vemuganti L. Raghavendra Rao ◽  
Aclan Dogan ◽  
Kellie K. Bowen ◽  
Kathryn G. Todd ◽  
Robert J. Dempsey

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