Acute renal failure in hypertensive disorders of pregnancy. Pregnancy outcome and remote prognosis in thirty-one consecutive cases

1991 ◽  
Vol 34 (1) ◽  
pp. 85-85
Author(s):  
BM Sibai ◽  
MA Villar ◽  
BC Mabie
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Pregnancy Outcome ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders

Hypertensive Disorders of Pregnancy and the Recent Increase in Obstetric Acute Renal Failure in Canada

2015 ◽  
Vol 35 (3) ◽  
pp. 136
Author(s):  
A. Mehrabadi ◽  
S. Liu ◽  
S. Bartholomew ◽  
J.A. Hutcheon ◽  
L.A. Magee ◽  
...  
Keyword(s):  
Renal Failure ◽  
Acute Renal Failure ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertensive Disorders ◽  
Recent Increase

Senior-Løken syndrome misdiagnosed as nephrosclerosis related to hypertensive disorders of pregnancy

2020 ◽  
Vol 13 (10) ◽  
pp. e236137
Author(s):  
Yuri Hirai ◽  
Aya Mizumoto ◽  
Kensuke Mitsumoto ◽  
Takashi Uzu
Keyword(s):  
Renal Failure ◽  
Molecular Genetic ◽  
Homozygous Deletion ◽  
Molecular Genetic Analysis ◽  
Inherited Disease ◽  
Hypertensive Disorders Of Pregnancy ◽  
Gene Encoding ◽  
Hypertensive Disorders ◽  
Basement Membrane Thickening ◽  
End Stage

A 31-year-old woman with retinitis pigmentosa who had been diagnosed with renal failure due to nephrosclerosis related to hypertensive disorders of pregnancy was referred to our hospital to prepare for renal replacement therapy. Ultrasonography and MRI of the kidneys revealed multiple corticomedullary cysts. A renal biopsy showed that the tubules were tortuous and atrophic with segmented tubular basement membrane thickening. These findings indicated that she had Senior-Løken syndrome. A molecular genetic analysis was performed, and homozygous deletion of the gene encoding nephronophthisis-1 was found. Thus, the clinical diagnosis of Senior-Løken syndrome was genetically confirmed. Because her renal function was gradually worsening, she was scheduled to undergo living donor kidney transplantation. Senior-Løken syndrome, which is recognised as a very rare paediatric inherited disease characterised by nephronophthisis and eye problems, can cause adult-onset end-stage renal failure.

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