The hypertension detection and follow-up program design, methods, and baseline characteristics and blood pressure response of the study population

1986 ◽  
Vol 29 (3) ◽  
pp. 11-28 ◽  
Author(s):  
Barry R. Davis ◽  
Charles E. Ford ◽  
Richard D. Remington ◽  
Rose Stamler ◽  
C. Morton Hawkins
Keyword(s):  
Blood Pressure ◽  
Program Design ◽  
Blood Pressure Response ◽  
Design Methods ◽  
Pressure Response ◽  
Hypertension Detection ◽  
Study Population ◽  
Baseline Characteristics

Abstract 2552: Hypertrophic Cardiomyopathy in Children: Do Adult Risk Factors for Cardiac Death Apply

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Jamie A Decker ◽  
Joseph W Rossano ◽  
E. O’Brian Smith ◽  
Bryan C Cannon ◽  
Sarah K Clunie ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Hypertrophic Cardiomyopathy ◽  
Family History ◽  
Blood Pressure Response ◽  
Left Ventricular ◽  
Pressure Response ◽  
Systemic Hypertension ◽  
Response To Exercise

Introduction : Annual mortality in children with hypertrophic cardiomyopathy (HCM) has been reported to be 1– 6%. Risk factors for death in adult HCM patients have been characterized; their application to pediatric HCM is unknown. The purpose of this study was to correlate adult risk factors with outcomes in our pediatric population using a standard management strategy. Methods : A retrospective cohort study of children with HCM was performed. Death and cardiac transplant were the primary outcomes. Diagnosis was based on asymmetric septal or concentric hypertrophy as determined by echocardiography. Exclusion criteria included: genetic syndrome, mitochondrial or metabolic disorder, infants of diabetic mothers, congenital heart disease, systemic hypertension, diagnosis >18 years of age, or follow-up <1 year. Results : From 1/1/85 to 10/1/06, 96 patients met inclusion criteria. Mean age at diagnosis was 10.6 ± 5.4 years. Mean follow-up was 6.5 ± 5.2 years. 11 patients had an adverse outcome (7 deaths, 4 transplants). Kaplan-Meier analysis predicts an 82% survival over 20 years. Evidence of left ventricular outflow tract obstruction (LVOTO) occurred in =6% of patients, syncope in 23% and a family history for malignant HCM in 17%. Aborted sudden death occurred in 6%. 10% had non-sustained ventricular tachycardia. 58% of patients underwent at least one exercise treadmill test. All patients were restricted from strenuous activity. 95% of patients were on a β-blocker or calcium channel blocker, with 10% on both. Additional intervention depended on symptoms, family history, and degree of LVOTO. 17% had an implantable defibrillator (ICD). 10% were given a pacemaker due to LVOTO, and 5% underwent left ventricular myectomy. Only extreme LVH (>6 z-scores for BSA) and a blunted blood pressure response to exercise were statistically significant for worse outcomes (both p<0.02). Conclusions : A low mortality/transplantation rate occurred in children with isolated HCM whose management consisted of exercise restriction and medication, with or without an ICD. Management that included myectomy was uncommon. Patients with extreme LVH and a blunted blood pressure response to exercise are high-risk individuals.

scholarly journals A COMPARATIVE STUDY OF BLOOD PRESSURE IN MEDITATORS AND NON MEDITATORS

2019 ◽  
Vol 3 (12) ◽  
Author(s):  
A.R. Vidyullatha ◽  
D. Lavanya ◽  
G.Benny Sanfrancisco
Keyword(s):  
Quality Of Life ◽  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Developing Countries ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Autonomic Functions ◽  
Industrialized Nations ◽  
Study Population

Aims and Objectives: Cardiovascular disease (CVD) is the leading cause of death and disability in industrialized nations, as well as in developing countries, Leading to premature morbidity and mortality, and to preventable losses of employment, earnings, and quality of life. The present study includes the effect of meditation on blood pressure. Material and Methods: The study population of 100 subjects out of which 50 were Non-meditators and 50 were meditators attending sainath pathanjali yoga centre. Using sphygmomanometer and stethoscope Blood pressure response to standing was recorded. Results: The improvements in autonomic functions are seen meditators in this study which are similar to other studies done on meditation and yoga. Conclusion: In present study Blood pressure response to standing difference of both systolic &diastolic was significantly higher in meditators than in nonmeditators on change of posture from supine to erect indicating decreased sympathetic dominance. Keywords: Cardiovascular disease, Systolic blood pressure, Diastolic blood pressure.

Factors Associated With an Abnormal Blood Pressure Response During Exercise After Coarctation Repair

2021 ◽  
Vol 13 (1) ◽  
pp. 53-59
Author(s):  
Mia Pivirotto ◽  
Michael F. Swartz ◽  
Megan B. McGreevy ◽  
Nader Atallah-Yunes ◽  
Jill M. Cholette ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Aortic Arch ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Exercise Stress ◽  
Factors Associated ◽  
Coarctation Repair ◽  
Brachiocephalic Trunk ◽  
Aortic Arch Repair

Background Although resting blood pressures following aortic arch repair or the extended end-to-end anastomosis (EEA) repair for coarctation can be physiologic, factors associated with an abnormal blood pressure response after exercise are unknown. We measured blood pressure gradients following exercise in children who had undergone previous repair in accordance with a surgical selection algorithm and sought to identify factors associated with an abnormal blood pressure response. Methods In accordance with our practice's surgical algorithm for repair of coarctation, infants were stratified to aortic arch repair when the distal transverse arch-to-left carotid artery ratio (DTA:LCA) ≤ 1.0, or when a brachiocephalic trunk or intra-cardiac lesion requiring repair was present. A thoracotomy and EEA were otherwise used. A follow-up exercise stress test (EST) measured the arm:leg blood pressure gradient after exercise, and a gradient ≥ 20 mm Hg was defined as an abnormal blood pressure response. Results Thirty-seven infants who had previously undergone coarctation repair (aortic arch repair-19, EEA-18) completed an EST at 12.3 ± 2.2 years of age. Thirteen (35%) children (aortic arch repair-5, EEA-8; p = .3) exhibited an abnormal blood pressure response. Factors associated with an abnormal blood pressure response included: smaller DTA:LCA ratios prior to repair (1.0 ± .2 vs. 1.2 ± .3; p = .04) and greater body weight at the time of EST (57.5 ± 19.1 vs. 40.9 ± 15.6 kg; p = .03). Conclusion An abnormal blood pressure response following exercise is associated with smaller DTA:LCA ratios at the time of repair and increased weight during follow-up suggesting that patients with these factors warrant close observation.

Follow-up of normotensive men with exaggerated blood pressure response to exercise

1983 ◽  
Vol 106 (2) ◽  
pp. 316-320 ◽  
Author(s):  
Ronald A. Dlin ◽  
Nora Hanne ◽  
Donald S. Silverberg ◽  
Oded Bar-Or
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Response To Exercise

Abnormal Blood Pressure Response to Excercise in Borderline Hypertension: A Two Year Follow-up Study

1991 ◽  
Vol 4 (3 Pt 1) ◽  
pp. 271-273 ◽  
Author(s):  
G. Guerrera ◽  
D. Melina ◽  
F. Colivicchi ◽  
A. Santoliquido ◽  
G. Guerrera ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Borderline Hypertension ◽  
Follow Up Study

Exaggerated exercise blood pressure response in middle-aged men as a predictor of future blood pressure: a 10-year follow-up

2016 ◽  
Vol 38 (8) ◽  
pp. 696-700 ◽  
Author(s):  
Katsuyuki Ito ◽  
Masataka Iwane ◽  
Nobuyuki Miyai ◽  
Yukiko Uchikawa ◽  
Koichi Mugitani ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Middle Aged ◽  
Exercise Blood Pressure

Abstract 485: An Urologic-nephrologic Based Approach to Resistant Hypertension: Early Clinical Experience with a Non-vascular Treatment

Hypertension ◽  
2014 ◽  
Vol 64 (suppl_1) ◽  
Author(s):  
Richard Heuser ◽  
Terry Buena ◽  
Randy Cooper ◽  
Adam Gold ◽  
Rahul Rao ◽  
...  
Keyword(s):  
Blood Pressure ◽  
General Anesthesia ◽  
Resistant Hypertension ◽  
Blood Pressure Response ◽  
Pressure Response ◽  
Radiofrequency Energy ◽  
Small Series ◽  
Number Of Patients ◽  
Diseased Kidney

The Symplicity HTN-3 recently failed to meet its primary efficacy endpoint in blood pressure reduction. The natural orifice denervation system developed by Verve Medical directs radiofrequency energy to the renal pelvic space where the preponderance of afferent nerves originate. We have previously demonstrated the feasibility of the Verve Medical NephroBlate to ablate these nerves. We developed a protocol to treat a small number of patients (n=3, 4 kidneys) undergoing elective nephrectomy at Muljibhai Patel Urological Hospital on Nadiad, India. We treated three patients with end stage kidney disease prior to explants of the affected diseased kidney. One patient was pre-renal transplant and had both kidneys treated. One week after fluoroscopically aided transurethral treatment with the NephroBlate™ device, the previously planned nephrectomy was performed. Procedure time was between 9 to 15 minutes and no adverse effects were recorded. The histopathological results in all cases showed a significant destruction of the peri-pelvic nerves from the renal pelvic space to the serosa (1.75mm). With a significant elimination of most of the afferent and efferent nerves in the treated area(approximately 1cm), and no change to the adjacent nerves in the control segments in the histopathologic specimens, as well as a safe and painless procedure for the patients, we proceeded with our clinical studies on resistant hypertensive patients. As in the diseased kidney study, the procedures were done under general anesthesia. Within 30 seconds of treatment of the first kidney, a blood pressure response was noted (reduction of mean systolic blood pressure 44mmHg, reduction of mean diastolic blood pressure 13mmHg). Following the procedure, none of the patients had significant pain or bleeding. At one month follow-up, the patients continue to be normotensive with no renal issues. This very small series did not exclude any patients with renal disease and no patients received any anticoagulants. The blood pressure response was immediate and occurred while the patients were under general anesthesia. In this small series of humans treated with limited follow-up, we see a promising nonvascular alternative for renal denervation for treatment for resistant hypertension.

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