Inhomogeneity effects on O2 and CO pulmonary diffusing capacity estimates by steady-state methods. Theory

1971 ◽  
Vol 13 (1) ◽  
pp. 1-22 ◽  
Author(s):  
A. Chinet ◽  
J.L. Micheli ◽  
P. Haab
Keyword(s):  
Steady State ◽  
Diffusing Capacity ◽  
Pulmonary Diffusing Capacity ◽  
Capacity Estimates

Comparison of steady state pulmonary diffusing capacity estimates for O2 and CO in dogs

1980 ◽  
Vol 42 (1) ◽  
pp. 43-59 ◽  
Author(s):  
J. Savoy ◽  
M.-C. Michoud ◽  
M. Robert ◽  
J. Geiser ◽  
P. Haab ◽  
...  
Keyword(s):  
Steady State ◽  
Diffusing Capacity ◽  
Pulmonary Diffusing Capacity ◽  
Capacity Estimates

Effect of exercise on pulmonary diffusing capacity

1963 ◽  
Vol 18 (3) ◽  
pp. 447-456 ◽  
Author(s):  
G. M. Turino ◽  
E. H. Bergofsky ◽  
R. M. Goldring ◽  
A. P. Fishman
Keyword(s):  
Carbon Monoxide ◽  
Young Adults ◽  
Steady State ◽  
Body Position ◽  
Diffusing Capacity ◽  
Pulmonary Diffusing Capacity ◽  
Graded Exercise ◽  
Normal Man ◽  
The Difference

The effect of graded exercise on the pulmonary diffusing capacity for both oxygen and carbon monoxide measured simultaneously was studied in healthy young adults by steady-state methods. Pulmonary diffusing capacity for oxygen increases progressively with increasing severity of exercise; it exceeds the DlCO at high levels of exercise by amounts greater than can be accounted for by the difference in diffusivity of the test gases. Diffusing capacity for carbon monoxide increases less than DlOO2 for comparable grades of exercise but no definite plateau value could be established. The supine or upright body position does not influence the values of either DlOO2 or DlCO during exercise. Diffusing capacity of the lung for oxygen does not limit the maximum levels of exercise which may be achieved by normal man. Submitted on August 6, 1962

Relationship of increased breath-holding diffusing capacity to ventilation in exercise

1963 ◽  
Vol 18 (4) ◽  
pp. 794-797 ◽  
Author(s):  
Joseph C. Ross ◽  
Ronald W. Reinhart ◽  
John F. Boxell ◽  
Leroy H. King
Keyword(s):  
Steady State ◽  
Ventilation Rate ◽  
The Other ◽  
Breath Holding ◽  
Diffusing Capacity ◽  
Voluntary Hyperventilation ◽  
Pulmonary Diffusing Capacity ◽  
Pulmonary Capillaries ◽  
The Mean ◽  
Relationship Of

Pulmonary diffusing capacity (Dl), as measured by all techniques, increases with exercise possibly due to an increase in the volume of blood in pulmonary capillaries (Vc), but the mechanism for the latter is not known. Previous studies have indicated that the steady-state Dl can be increased by hyperventilation alone, enough possibly to account for the increase in Dl as measured by this method with exercise. On the other hand, breath-holding Dl is not increased by voluntary hyperventilation preceding the measurement. The present study was carried out to determine whether or not the increase in ventilation rate is a necessary part of a combination of factors which account for the rise in Dl during exercise. In this study breath-holding Dl was measured in five subjects. All of the five subjects studied had an increase in Dl during exercise when ventilation was voluntarily restrained to the resting level, and the mean increase was as great as the mean increase during the same amount of exercise with normal unrestricted breathing. The increase in Dl when breathing was restricted during exercise could not be accounted for by differences in alveolar volumes or by differences in alveolar O2 and CO2 tensions in the two situations. This study demonstrates that increase in ventilation preceding the measurement is not a determinant of the increase in breath-holding Dl with exercise Submitted on January 7, 1963

Effect of Body Temperature on Pulmonary Gas Exchange

1957 ◽  
Vol 188 (2) ◽  
pp. 355-359 ◽  
Author(s):  
A. B. Otis ◽  
James Jude
Keyword(s):  
Carbon Dioxide ◽  
Carbon Monoxide ◽  
Steady State ◽  
Body Temperature ◽  
Gas Exchange ◽  
Diffusing Capacity ◽  
Body Temperatures ◽  
Pulmonary Diffusing Capacity ◽  
Normal Body ◽  
Anesthetized Dogs

Measurements were made of the arterial-alveolar carbon dioxide gradient in anesthetized dogs at body temperatures ranging from normal down to 16°C. Pulmonary diffusing capacity was determined by a steady-state carbon monoxide method in anesthetized dogs at normal body temperatures and at 25°C. From the results it is concluded that although diffusing capacity is reduced at low body temperatures, it is still adequate for transfer of both CO2 and O2 because the metabolic requirements for gas exchange are also reduced.

scholarly journals An Assessment of the Steady-state Carbon Monoxide Method of Estimating Pulmonary Diffusing Capacity

Thorax ◽  
1959 ◽  
Vol 14 (2) ◽  
pp. 166-175 ◽  
Author(s):  
J. MacNamara ◽  
F. J. Prime ◽  
J. D. Sinclair
Keyword(s):  
Carbon Monoxide ◽  
Steady State ◽  
Diffusing Capacity ◽  
Pulmonary Diffusing Capacity
Sign in / Sign up

Export Citation Format

Share Document