Electron microscopy and other physical methods for the characterization of extracellular matrix components: Laminin, fibronectin, collagen IV, collagen VI, and proteoglycans

1987 ◽  
pp. 3-78 ◽  
Author(s):  
Jürgen Engel ◽  
Heinz Furthmayr
Keyword(s):  
Electron Microscopy ◽  
Extracellular Matrix ◽  
Collagen Iv ◽  
Collagen Vi ◽  
Physical Methods ◽  
Extracellular Matrix Components ◽  
Matrix Components

scholarly journals Metabolic Dysregulation and Adipose Tissue Fibrosis: Role of Collagen VI

2008 ◽  
Vol 29 (6) ◽  
pp. 1575-1591 ◽  
Author(s):  
Tayeba Khan ◽  
Eric S. Muise ◽  
Puneeth Iyengar ◽  
Zhao V. Wang ◽  
Manisha Chandalia ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Adipose Tissue ◽  
Whole Body ◽  
Positive Energy ◽  
Main Function ◽  
Collagen Vi ◽  
Free Expansion ◽  
Tissue Fibrosis ◽  
Extracellular Matrix Components ◽  
Matrix Components

ABSTRACT Adipocytes are embedded in a unique extracellular matrix whose main function is to provide mechanical support, in addition to participating in a variety of signaling events. During adipose tissue expansion, the extracellular matrix requires remodeling to accommodate adipocyte growth. Here, we demonstrate a general upregulation of several extracellular matrix components in adipose tissue in the diabetic state, therefore implicating “adipose tissue fibrosis” as a hallmark of metabolically challenged adipocytes. Collagen VI is a highly enriched extracellular matrix component of adipose tissue. The absence of collagen VI results in the uninhibited expansion of individual adipocytes and is paradoxically associated with substantial improvements in whole-body energy homeostasis, both with high-fat diet exposure and in the ob/ob background. Collectively, our data suggest that weakening the extracellular scaffold of adipocytes enables their stress-free expansion during states of positive energy balance, which is consequently associated with an improved inflammatory profile. Therefore, the disproportionate accumulation of extracellular matrix components in adipose tissue may not be merely an epiphenomenon of metabolically challenging conditions but may also directly contribute to a failure to expand adipose tissue mass during states of excess caloric intake.

Immunohistochemical Characterization of Cellular and Extracellular Matrix Components of Oral Mucoceles

2014 ◽  
Vol 117 (2) ◽  
pp. e211
Author(s):  
ADNA CONCEIÇÃO BARROS ◽  
JAMILE GOMES CONCEIÇÃO ◽  
FLÁVIA CALÓ XAVIER DE AQUINO ◽  
LUCIANA MARIA PEDREIRA RAMALHO ◽  
CLARISSA ARAÚJO SILVA GURGEL ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Extracellular Matrix Components ◽  
Matrix Components

scholarly journals Characterization of extracellular matrix components from the desiccation-tolerant cyanobacterium Nostoc commune

2018 ◽  
Vol 64 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Kaori Inoue-Sakamoto ◽  
Yasunori Tanji ◽  
Minami Yamaba ◽  
Takumi Natsume ◽  
Takuya Masaura ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Nostoc Commune ◽  
Extracellular Matrix Components ◽  
Matrix Components

Characterization of extracellular matrix components in the limbal epithelial stem cell compartment

2007 ◽  
Vol 85 (6) ◽  
pp. 845-860 ◽  
Author(s):  
U. Schlötzer-Schrehardt ◽  
T. Dietrich ◽  
K. Saito ◽  
L. Sorokin ◽  
T. Sasaki ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Stem Cell ◽  
Cell Compartment ◽  
Epithelial Stem Cell ◽  
Stem Cell Compartment ◽  
Extracellular Matrix Components ◽  
Matrix Components

Immunohistochemical characterization of extracellular matrix components of granulosa cell tumor of ovary

1994 ◽  
Vol 44 (3) ◽  
pp. 205-212 ◽  
Author(s):  
Nili Meng ◽  
Nobuo Nakashima ◽  
Tetsuro Nagasaka ◽  
Toshiaki Fukatsu ◽  
Yoshiharu Nara ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Granulosa Cell ◽  
Granulosa Cell Tumor ◽  
Cell Tumor ◽  
Extracellular Matrix Components ◽  
Matrix Components
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