Influence of frying fat on mutagenic activity in lean pork meat

1986 ◽  
Vol 171 (2-3) ◽  
pp. 115-121 ◽  
Author(s):  
Lena Nilsson ◽  
Eva Övervik ◽  
Lillemor Fredholm ◽  
Östen Levin ◽  
Carl-Erik Nord ◽  
...  
Keyword(s):  
Mutagenic Activity ◽  
Pork Meat ◽  
Frying Fat ◽  
Lean Pork

Gastrointestinal digestion and cecal fermentation of a mixed gel of lean pork meat and resistant starch in mice

2020 ◽  
Vol 11 (8) ◽  
pp. 6834-6842
Author(s):  
Xi-xi Wang ◽  
Xia Yu ◽  
Yu Wang ◽  
Pei-jun Li ◽  
Bao-cai Xu ◽  
...  
Keyword(s):  
Resistant Starch ◽  
Pork Meat ◽  
Gastrointestinal Digestion ◽  
Lean Meat ◽  
Lean Pork

A mixed gel of lean meat and RS promoted gastrointestinal digestion and cecalfermentation in mice.

Mutagenic activity in smoke formed during broiling of lean pork at 200, 250 and 300°C

1988 ◽  
Vol 207 (3-4) ◽  
pp. 199-204 ◽  
Author(s):  
Ingrid Berg ◽  
Eva Övervik ◽  
Carl-Erik Nord ◽  
Jan-Åke Gustafsson
Keyword(s):  
Mutagenic Activity ◽  
Lean Pork

Mutagenicity in Pulp and Paper Mill Effluents and in Recipient

1988 ◽  
Vol 20 (2) ◽  
pp. 143-152 ◽  
Author(s):  
A. Langi ◽  
M. Priha
Keyword(s):  
Activated Sludge ◽  
Mutagenic Activity ◽  
Chinese Hamster Ovary Cells ◽  
Chinese Hamster ◽  
Paper Mill ◽  
Pulp And Paper ◽  
Pulp And Paper Mill ◽  
Sludge Treatment ◽  
Paper Mill Effluents ◽  
Kraft Mill

The mutagenic properties of pulp and paper mill effluents were studied in three mills: bleached kraft mill with aerated lagoon treatment (Mill 1), bleached kraft mill with activated sludge treatment (Mill 2) and mechanical pulp/paper mill (Mill 3). Both treated and untreated effluents, process streams and molecular fractions were tested for mutagenicity (Ames test. Salmonella typhimurium TA100 and SCE sister chromatid exchange test, Chinese hamster ovary cells). To verify the potential environmental effects the mutagenic activity of concentrated recipient lake water (Mill 2) was also studied. The Ames mutagenicity of the bleached kraft mill effluent (BKME) originated from the first chlorination filtrate, SCE mutagenicity also occurred in the alkali extraction stage filtrate (Mill 1). No Ames mutagenicity was detected in the paper mill effluent, but it was SCE mutagenic. Activated sludge treatment of BKME removed both Ames and SCE mutagenicity, but the aerated lagoon treated BKME was still SCE mutagenic. No mutagenic activity was detected in the recipient water concentrates.

Antiproliferative and Genotoxic Action of an Underexploited Organoteluran Derivative on Sarcoma 180 Cells

2020 ◽  
Vol 20 ◽  
Author(s):  
Maria L.L. Barreto do Nascimento ◽  
Antonielly Campinho dos Reis ◽  
José V.O. Santos ◽  
Helber A. Negreiros ◽  
Felipe C. Carneiro da Silva ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Nuclear Division ◽  
Micronucleus Test ◽  
Mutagenic Activity ◽  
Chemical Compounds ◽  
Negative Control ◽  
Nuclear Division Index ◽  
Apoptosis And Necrosis ◽  
Genotoxicity Tests ◽  
Genotoxic Action

Background: The search for novel metallic chemical compounds with toxicogenic effects have been of great importance for more efficient cancer treatment. Objective: The study evaluated the cytotoxic, genotoxic and mutagenic activity of organoteluran RF07 in S-180 cell line. Methods: The bioassays used were cell viability with 3-(4,5-dimethyl-2-thiazole)-2,5-diphenyl-2-H-tetrazolium bromide (MTT) test, evaluation of apoptosis and necrosis using fluorescence and flow cytometry, cytokinesis-block micronucleus test and comet assay. The compound was tested at 1; 2.5 and 5 µM. Results: The results showed the cytotoxicity of RF07 at concentrations of 2.5, 5, 10 and 20 µM when compared to the negative control. For genotoxicity tests, RF07 showed effects in all concentrations assessed by increased index and frequencies of damage and mutagenic alterations. The compound was also cytotoxic due to the significant decrease in nuclear division index, with significant values of apoptosis and necrosis. The results of fluorescence and flow cytometry showed apoptosis as the main type of cell death caused by RF07 at 5 µM, which is thought to avoid an aggressive immune response of the organism. Conclusion: In addition to cytotoxic and genotoxic effects, RF07 creates good perspectives for future antitumor formulations.

scholarly journals N-Nitroso Compounds and Mutagens in Chinese Fermented (Sour) Corn Pancakes

2002 ◽  
Vol 85 (5) ◽  
pp. 1052-1056 ◽  
Author(s):  
Frank D Groves ◽  
Haleem Issaq ◽  
Stephen Fox ◽  
Alan M Jeffrey ◽  
John Whysner ◽  
...  
Keyword(s):  
Stomach Cancer ◽  
Ames Test ◽  
Energy Analysis ◽  
Case Control Study ◽  
Mutagenic Activity ◽  
Nitroso Compounds ◽  
Positive Trend ◽  
Mutagenic Response ◽  
Control Study ◽  
Volatile Nitrosamines

Abstract Stomach cancer rates in rural Linqu County, Shandong Province, China, are exceptionally high. A previous case-control study revealed that the risk of stomach cancer was 30%higher among those who consumed sour (fermented) corn pancakes at least daily. A previous study of the sour pancakes reported volatile nitrosamines in most specimens, and almost half reportedly showed mutagenic activity. Few households currently consume sour pancakes, and the duration of fermentation has been shortened. We tested specimens of pancake batter and sour pancakes from Linqu County for mutagenic activity using the Ames test; for N-nitroso compounds (NOC) we used the Nitrolite–thermal energy analysis (TEA) method. Results of the Ames test were inconclusive: only 1 out of 15 cooked pancakes showed a positive mutagenic response, and all 15 batter specimens were negative; however, several batter specimens showed a weakly positive trend of mutagenicity with extract concentration. Our assay for total nitroso compounds was weakly positive in only 1 out of 15 specimens of sour pancake batter. That specimen was also tested by gas chromatography–TEA for nitrosaminoacids and volatile nitrosamines, but none were detected. It seems unlikely that the Chinese sour pancakes are significantly contaminated by NOC or other mutagens.

scholarly journals Frozen/thawed meat quality associated with muscle fiber characteristics of porcine longissimus thoracis et lumborum, psoas major, semimembranosus, and semitendinosus muscles

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Huilin Cheng ◽  
Sumin Song ◽  
Gap-Don Kim
Keyword(s):  
Meat Quality ◽  
Muscle Fiber ◽  
Shear Force ◽  
Muscle Fibers ◽  
Frozen Storage ◽  
Meat Color ◽  
Pork Meat ◽  
Psoas Major ◽  
The Relationship

AbstractTo evaluate the relationship between muscle fiber characteristics and the quality of frozen/thawed pork meat, four different muscles, M. longissimus thoracis et lumborum (LTL), M. psoas major (PM), M. semimembranosus (SM), and M. semitendinosus (ST), were analyzed from twenty carcasses. Meat color values (lightness, redness, yellowness, chroma, and hue) changed due to freezing/thawing in LTL, which showed larger IIAX, IIX, and IIXB fibers than found in SM (P < 0.05). SM and ST showed a significant decrease in purge loss and an increase in shear force caused by freezing/thawing (P < 0.05). Compared with LTL, SM contains more type IIXB muscle fibers and ST had larger muscle fibers I and IIA (P < 0.05). PM was the most stable of all muscles, since only its yellowness and chroma were affected by freezing/thawing (P < 0.05). These results suggest that pork muscle fiber characteristics of individual cuts must be considered to avoid quality deterioration during frozen storage.

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