scholarly journals A serpin from human tumor cells with direct lymphoid immunomodulatory activity: mitogenic stimulation of human tumor-infiltrating lymphocytes

1995 ◽  
Vol 1269 (1) ◽  
pp. 41-50 ◽  
Author(s):  
Beverly Z. Packard ◽  
Sylvia S. Lee ◽  
Eileen Remold-O'Donnell ◽  
Akira Komoriya
Keyword(s):  
Tumor Cells ◽  
Human Tumor ◽  
Tumor Infiltrating Lymphocytes ◽  
Immunomodulatory Activity ◽  
Human Tumor Cells ◽  
Mitogenic Stimulation ◽  
Infiltrating Lymphocytes ◽  
Stimulation Of

scholarly journals Lysis of Fresh Human Tumor Cells by Autologous Peripheral Blood Lymphocytes and Tumor-infiltrating Lymphocytes Activated hy PSK

1991 ◽  
Vol 82 (9) ◽  
pp. 1044-1050 ◽  
Author(s):  
Yoshitaka Kariya ◽  
Norihiko Okamoto ◽  
Takuya Fujimoto ◽  
Naoya Inoue ◽  
Takeshi Kihara ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Peripheral Blood ◽  
Human Tumor ◽  
Tumor Infiltrating Lymphocytes ◽  
Peripheral Blood Lymphocytes ◽  
Human Tumor Cells ◽  
Blood Lymphocytes ◽  
Infiltrating Lymphocytes

Immunosensitization of resistant human tumor cells to cytotoxicity by tumor infiltrating lymphocytes

2003 ◽  
Author(s):  
Patrick Frost ◽  
Randy Caliliw ◽  
Arie Belldegrun ◽  
Benjamin Bonavida
Keyword(s):  
Tumor Cells ◽  
Human Tumor ◽  
Tumor Infiltrating Lymphocytes ◽  
Human Tumor Cells ◽  
Infiltrating Lymphocytes

Growth Factor-Dependent Stimulation of Primary Human Tumor Cells

1990 ◽  
pp. 173-180
Author(s):  
H. Depenbrock ◽  
J. Trijssenaar ◽  
D. Neukam ◽  
H.-J. Meyer ◽  
M. Freund ◽  
...  
Keyword(s):  
Growth Factor ◽  
Tumor Cells ◽  
Human Tumor ◽  
Human Tumor Cells ◽  
Stimulation Of

scholarly journals Human neutrophil-mediated lysis of ovarian cancer cells

Blood ◽  
1989 ◽  
Vol 74 (2) ◽  
pp. 805-809 ◽  
Author(s):  
A Lichtenstein ◽  
M Seelig ◽  
J Berek ◽  
J Zighelboim
Keyword(s):  
Ovarian Cancer ◽  
Tumor Cells ◽  
Human Tumor ◽  
Ovarian Cancer Cells ◽  
Human Ovarian Cancer ◽  
Myristate Acetate ◽  
Human Tumor Cells ◽  
Effector Cells ◽  
Lethal Event ◽  
Stimulation Of

Abstract Because of recent questions concerning the sensitivity of human tumor cells to neutrophil-induced oxidative injury, we studied six freshly obtained human ovarian cancer (OC) specimens. Stimulation of neutrophils (PMNs) by phorbol myristate acetate (PMA) did not result in OC cytolysis during the first nine hours of incubation. However, three of six specimens were significantly lysed by stimulated PMNs when assay length was increased to 18 hours. Cytotoxicity was mediated by PMN production of reactive oxidative intermediates (ROIs). Presentation of ROIs to OC targets as preformed or enzymatically generated molecules in cell-free systems duplicated the enhanced lysis at 18 hours (as compared with six hours). Since addition of catalase at three or six hours did not inhibit enhanced lysis at 18 hours (achieved by PMNs or in cell-free systems), it appears that an initial ROI-mediated lethal event occurs early, but longer incubations are required for the event to become manifested as cell death. These data suggest that shorter assays may underestimate the potential of PMNs as effector cells against human tumor cells.

Early stimulation of acidification rate by novel cytotoxic pyridyl cyanoguanidines in human tumor cells: comparison with m-Iodobenzylguanidine

2000 ◽  
Vol 60 (6) ◽  
pp. 839-849 ◽  
Author(s):  
Sara Ekelund ◽  
Gunnar Liminga ◽  
Fredrik Björkling ◽  
Erik Ottosen ◽  
Charlotte Schou ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Human Tumor ◽  
Human Tumor Cells ◽  
Early Stimulation ◽  
Stimulation Of

Generation of specific anti-melanoma reactivity by stimulation of human tumor-infiltrating lymphocytes with MAGE-1 synthetic peptide

1994 ◽  
Vol 39 (2) ◽  
pp. 105-116 ◽  
Author(s):  
Michael L. Salgaller ◽  
Jeffrey S. Weber ◽  
Scott Koenig ◽  
John R. Yannelli ◽  
Steven A. Rosenberg
Keyword(s):  
Synthetic Peptide ◽  
Human Tumor ◽  
Tumor Infiltrating Lymphocytes ◽  
Infiltrating Lymphocytes ◽  
Stimulation Of
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