Effects of GABA and l-glutamic acid on the potassium-evoked in vitro release of substance P- and neurokinin A-like immunoreactivities are different in the rat striatum and substantia nigra

1989 ◽  
Vol 105 (1-2) ◽  
pp. 159-163 ◽  
Author(s):  
Christian Humpel ◽  
Alois Saria
Keyword(s):  
Substance P ◽  
Substantia Nigra ◽  
Glutamic Acid ◽  
In Vitro Release ◽  
Rat Striatum ◽  
Neurokinin A ◽  
Vitro Release

Opioid Control of the In Vitro Release of Cholecystokinin-Like Material from the Rat Substantia Nigra

1992 ◽  
Vol 58 (3) ◽  
pp. 916-922 ◽  
Author(s):  
J. J. Benoliel ◽  
A. Mauborgne ◽  
S. Bourgoin ◽  
J. C. Legrand ◽  
M. Hamon ◽  
...  
Keyword(s):  
Substantia Nigra ◽  
In Vitro Release ◽  
Vitro Release ◽  
Rat Substantia Nigra

The in vitro release of endogenousm-tyramine,p-tyramine and dopamine from rat striatum

1982 ◽  
Vol 7 (6) ◽  
pp. 705-716 ◽  
Author(s):  
Lillian E. Dyck ◽  
A. V. Juorio ◽  
A. A. Boulton
Keyword(s):  
In Vitro Release ◽  
Rat Striatum ◽  
Vitro Release

Study on in vitro release patterns of fentanyl-loaded PLGA microspheres

2003 ◽  
Vol 20 (5) ◽  
pp. 569-579 ◽  
Author(s):  
S.-A. Seo ◽  
G. Khang ◽  
J. M. Rhee ◽  
J. Kim ◽  
H. B. Lee
Keyword(s):  
In Vitro Release ◽  
Plga Microspheres ◽  
Vitro Release

Reliability of a Single β-Thromboglobulin Measurement in a Diabetic Population : Importance of PGE1 in Anticoagulant Mixture

1987 ◽  
Vol 57 (02) ◽  
pp. 201-204 ◽  
Author(s):  
P Y Scarabin ◽  
L Strain ◽  
C A Ludlam ◽  
J Jones ◽  
E M Kohner
Keyword(s):  
In Vitro Release ◽  
Mean Value ◽  
Reliable Estimate ◽  
Diabetic Patients ◽  
Single Measurement ◽  
Diabetic Population ◽  
The Difference ◽  
Vitro Release

SummaryDuring the collection of samples for plasma β-thromboglobulin (β-TG) determination, it is well established that artificially high values can be observed due to in-vitro release. To estimate the reliability of a single β-TG measurement, blood samples were collected simultaneously from both arms on two separate occasions in 56 diabetic patients selected for a clinical trial. From each arm, blood was taken into two tubes containing an anticoagulant mixture with (tube A) and without (tube B) PGE!. The overall mean value of B-TG in tube B was 1.14 times higher than in tube A (p <0.01). The markedly large between-arms variation accounted for the most part of within-subject variation in both tubes and was significantly greater in tube B than in tube A. Based on the difference between B-TG values from both arms, the number of subjects with artifically high B-TG values was significantly higher in tube B than in tube A on each occasion (overall rate: 28% and 14% respectively). Estimate of between-occasions variation showed that B-TG levels were relatively stable for each subject between two occasions in each tube. It is concluded that the use of PGEi decreases falsely high B-TG levels, but a single measurement of B-TG does not provide a reliable estimate of the true B-TG value in vivo.

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