The effects of intrauterine growth retardation on the development of the Purkinje cell dendritic tree in the cerebellar cortex of fetal sheep: A note on the ontogeny of the Purkinje cell

1988 ◽  
Vol 6 (5) ◽  
pp. 461-469 ◽  
Author(s):  
Sandra Rees ◽  
Richard Harding
Keyword(s):  
Purkinje Cell ◽  
Cerebellar Cortex ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Dendritic Tree ◽  
Fetal Sheep ◽  
Intrauterine Growth

Structural Changes in Cerebellar Cortex Induced by Intrauterine Growth Retardation in the Rat

1981 ◽  
Vol 39 ◽  
pp. 536-537
Author(s):  
Alfredo Feria-Velasco ◽  
Guadalupe Tapia-Arizmendi
Keyword(s):  
Cerebellar Cortex ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Structural Changes ◽  
Growth Failure ◽  
Genetic Alterations ◽  
Sprague Dawley ◽  
Intrauterine Growth ◽  
The Central Nervous System ◽  
Placental Blood

Intrauterine growth retardation (IUGR), both in human and experimental animals, can be produced by two types of factors : intrinsic and extrinsic. Intrinsic growth failure may result from congenital and/or genetic alterations. Two main categories of extrinsic growth failure have been described: a) produced by interfering with placental blood flow to fetuses; and b) produced by maternal dietary restriction. In both types, alterations of neurological functions are observed, mainly related to learning and memory.In various models of IUGR, the cerebellum is more affected than the other structures of the central nervous system,according to biochemical studies carried out by different authors.For the present work, IUGR was produced in Sprague Dawley rats according to Wigglesworth's method by ligation of one uterine artery at the 15th gestational day. The products and placentas were obtained by cæsarean section at the 21st gestational day to be weighed and studied with the light and electron microscope. The data here presented correspond to the ultrastructural study of cerebellar cortex of neonates perfused intravascularly with 2.5% buffered-glutaraldehyde, postfixed with buffered osmium tetroxide and processed for transmission electron microscopy.

Intrauterine growth retardation and the circulatory responses to acute hypoxemia in fetal sheep

1989 ◽  
Vol 161 (6) ◽  
pp. 1576-1579 ◽  
Author(s):  
Barry S. Block ◽  
Donald H. Schlafer ◽  
Richard A. Wentworth ◽  
Lois A. Kreitzer ◽  
Peter W. Nathanielsz
Keyword(s):  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Fetal Sheep ◽  
Intrauterine Growth

Imbalance in the system L-arginin-NO in pathogenesis of obstetric complications and intrauterine growth retardation (Literature review)

2016 ◽  
pp. 43-47
Author(s):  
O.V. Basystyi ◽  
Keyword(s):  
Nitric Oxide ◽  
Literature Review ◽  
Growth Retardation ◽  
Intrauterine Growth Retardation ◽  
Obstetric Complications ◽  
Pathogenetic Role ◽  
Intrauterine Growth ◽  
System L ◽  
Nitric Oxide Deficiency

The data of domestic and foreign literature on etiology, pathogenesis and intrauterine growth retardation diagnosis are presented in the paper. It highlights pathogenetic role of nitric oxide deficiency in case of obstetric complications and intrauterine growth retardation. Key words: intrauterine growth retardation (IUGR), system L-arginin–NO, obstetric complications.

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