structural development
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Author(s):  
A. M. H. Ansar ◽  
A. H. M. Din ◽  
A. S. A. Latip ◽  
M. N. M. Reba

Abstract. Technology advancement has urged the development of Interferometric Synthetic Aperture Radar (InSAR) to be upgraded and transformed. The main contribution of the InSAR technique is that the surface deformation changes measurements can achieve up to millimetre level precision. Environmental problems such as landslides, volcanoes, earthquakes, excessive underground water production, and other phenomena can cause the earth's surface deformation. Deformation monitoring of a surface is vital as unexpected movement, and future behaviour can be detected and predicted. InSAR time series analysis, known as Persistent Scatterer Interferometry (PSI), has become an essential tool for measuring surface deformation. Therefore, this study provides a review of the PSI techniques used to measure surface deformation changes. An overview of surface deformation and the basic principles of the four techniques that have been developed from the improvement of Persistent Scatterer Interferometric Synthetic Aperture Radar (PSInSAR), which is Small Baseline Subset (SBAS), Stanford Method for Persistent Scatterers (StaMPS), SqueeSAR and Quasi Persistent Scatterer (QPS) were summarised to perceive the ability of these techniques in monitoring surface deformation. This study also emphasises the effectiveness and restrictions of each developed technique and how they suit Malaysia conditions and environment. The future outlook for Malaysia in realising the PSI techniques for structural monitoring also discussed in this review. Finally, this review will lead to the implementation of appropriate techniques and better preparation for the country's structural development.


2022 ◽  
Author(s):  
Barbara Luzia Santos de Oliveira Faro ◽  
Priscila Sanjuan de Medeiros-Sarmento ◽  
Norma Ely Santos Beltrão ◽  
Paulo Weslem Portal Gomes ◽  
Ana Cláudia Caldeira Tavares-Martins

Abstract Mangroves in the Amazon are influenced by several environmental conditions that determine the composition and structural development of the arboreal flora, which results in different distribution patterns. In this study, we sought to answer two questions: (1) what is the composition and structure of the mangroves near the mouth of the Amazon River in Marajó Island? (2) Are the fringe and inland mangroves more similar or dissimilar in terms of floristic composition? For this, we delimited a fringe zone and an inland zone about 1 km apart from each other. In each zone, we distributed five 400-m2 plots. The individuals were grouped into diameter and height classes and structural and phytosociological parameters were calculated. Ten species were recorded in the mangroves, of which seven are typical of white-water (várzea) and black-water (igapó) flooded forest ecosystems. We believed the adjacent ecosystems and the hydrological network are inducing the establishment of such species. The composition and structure of mangroves did not differ statistically between zones, and the degree of similarity may be a result of similar environmental factors in these zones such as low relief and high frequency of macrotides. We conclude that the vegetation of the studied mangroves has a major influence of the fluvial-marine system of the great rivers of the Amazon associated with a diversity of ecosystems that, together, generate greater floristic richness when compared to mangroves in other regions.


Author(s):  
Qasim Zaheer ◽  
Tan Yonggang ◽  
Furqan Qamar

The structural development in bridge engineering along with efficiency have got much attention in few decades. Leading to the development, Optimization of structure established on mathematical analysis emerged mostly employed strategies for productive and sustainable design in the bridge engineering. Despite the widespread knowledge, there has yet to be a rigorous examination of recent structural optimization exploration development. Thus, the primary objectives of this paper are to critically review previous structural optimization research, provide a detailed examination of optimization goals and outline recent research field limitations and provide guidelines for future research proposal in the field of bridge engineering structural optimization. This article begins by outlining the relevance of efficiency and sustainability in the bridge construction, as well as the work done required for this review. Suitable papers are gathered and followed by a statistical analysis of the selected publications. Following that, the selected papers are evaluated in terms of the optimization targets as well as their spatial patterns. Structure's optimization four key steps, including modeling, optimization techniques, formulation of optimization concerns and computational tools, are also researched and examined in depth. Finally, research gaps in contemporary works are identified, as well as suggested guidance for future works.


2021 ◽  
Author(s):  
Hee-Hwan Wang ◽  
Seo-Yoon Moon ◽  
KaKyeong Kim ◽  
Hyun-Jin Kim ◽  
Woo-Young Ahn ◽  
...  

Early life stress (ELS), such as abuse, neglect, and maltreatment, is a well-known risk factor for mental illness. However, it is unclear how ELS affects the brain and cognitive development. Identifying specific relationships of ELS with the genetic and brain-related underpinnings of cognitive development may reveal biological mechanisms responsible for the negative impact of ELS and those that lead to individual differences in sensitivity (or resilience) to ELS. In this study, to investigate the interlinked processes of cognitive development, we analyzed the multimodal data of DNA genotypes, brain imaging (MRI), and neuropsychological assessment (NIH Toolbox) outcomes of 4,276 children (ages 9 to 10 years, European ancestry) from the Adolescent Brain Cognitive Development (ABCD) study. We estimated the genetic influence on cognitive capacity using genome-wide polygenic scores (GPSs). Our regression and mediation analyses revealed significant causal relationships for the gene-brain-cognition pathway: Brain structural development significantly mediated the genetic influence on cognitive development (partial mediation effect = 0.016, PFWE<0.001). Interestingly, within the triangular relationship, we found a significant moderation effect of abuse only on the gene-to-brain pathway (Index of Moderated Mediation = -0.007; 95% CI= -0.012 ~ -0.002; PFWE<0.05). These findings indicate the negative modulatory effects of ELS on the genetic influence on brain structural development that lead to disadvantageous neurocognitive development in prepubertal children.


2021 ◽  
Author(s):  
Naoki Yamamoto ◽  
Rintaro Inoue ◽  
Yoshiteru Makino ◽  
Naoya Shibayama ◽  
Akira Naito ◽  
...  

Amyloid fibrils are abnormal protein aggregates that relate to a large number of amyloidoses and neurodegenerative diseases. The oligomeric precursors, or prefibrillar intermediates, which emerge prior to the amyloid fibril formation, have been known to play a crucial role for the formation. Therefore, it is essential to elucidate the mechanisms of the structural development of the prefibrillar intermediates and ways to prevent its fibril formation. An insulin-derived peptide, insulin B chain, has been known for its stable accumulation of the prefibrillar intermediates. In this study, structural development of B chain prefibrillar intermediates was monitored by transmission electron microscopy and small-angle X-ray scattering combined with size exclusion chromatography and solid-state NMR spectroscopy to elucidate the stability and secondary structure. We further tracked its inhibition process by fibrinogen (Fg), which has been known to effectively prevent the amyloid fibril formation of B chain. We demonstrated that prefibrillar intermediates are wavy structures with low β-sheet content, growing in a multistep manner toward the nucleation for the amyloid fibril formation. In the presence of Fg, the formation of the prefibrillar intermediates slowed down by forming specific complexes. These observations suggest that the prefibrillar intermediates serve as reaction fields for the nucleation and its propagation for the amyloid fibril formation, whereas the inhibition of prefibrillar intermediate elongation by Fg is the significant factor to suppress the fibril formation. We propose that the obtained molecular picture could be a general inhibition mechanism of the amyloid fibril formation by the inhibitors.


2021 ◽  
pp. 1-24
Author(s):  
Oyeniyi Abe

Abstract This article examines the framework of Nigeria's local content laws and policy, and the implications for sustainable development. The legislation is geared towards safeguarding local productivity and aiding the progressive aspirations of Nigeria's citizens. While commendable in principle, there have been questions about policy articulation, implementation and enforcement mechanisms, especially with regard to the Sustainable Development Goals. The article examines the local content legislation in Nigeria, and how policies have shaped the community-corporate nexus. This exposes the challenges facing extractive resource governance in a jurisdiction such as Nigeria and the discourses that have permeated legal scholarship on the practical deference to local content by non-state actors. It considers that well designed and implemented local content requirements are catalysts for structural development. To achieve sustainable development of its extractive sector, Nigeria requires state-led determination to stimulate economic growth and development. The article argues for continuous consultation as a bedrock for meaningful engagement.


Author(s):  
O. V. Morozov ◽  
M. A. Vasiliev

In the practice of state governance economic development is usually estimated by comparing macro-economic indicators for the period being evaluated with relevant preceding periods. The article studies a non-conventional – structural approach to estimating the development of sectoral structure of Russian economy. The period of 10 years, i. e. from 2011 to 2020 was analyzed, at the same time the possibility of accelerated development in the medium-term (2023) and long-term (2036) periods was investigated. The authors provide theoretical foundations of the research, indicators of structural development, the procedure and algorithms of their estimation. The criterion and quality model of passing-over from the actual condition to the optimal combination of sector scales were identified. By comparing the actual and model (estimated) indicators of sector scales the trend and nature of structural development of national economy were evaluated, as well as its capacity to develop rapidly in future periods. The findings show that harmonization of indicators of diversity and uniformity, changeability and stability in sectoral structure forms a structural precondition for the development of national economy. These indicators can be used by bodies of state governance in the process of devising strategy of accelerated development of economy in general and its industries.


2021 ◽  
Vol 20 (10) ◽  
pp. 103-116
Author(s):  
Natalya S. Epifanova ◽  
Vladimir N. Akulinin

The purpose of this article is to study border trade in the regions of Russia and the provinces of China. It is shown that in recent years there have been negative trends in border trade, leading to its reduction. Therefore, Russian regions bordering with China should transform into separate objects of regional policy, while also forming a legislative framework for border interaction in all its main spheres: trade, humanitarian cooperation, science and education, and others. In border cooperation with China, special emphasis should be placed on cooperation in the innovation sphere, as well as on improving the quality of exported goods and services and promoting infrastructure projects. Border trade between the regions of Russia and China is built mainly on trade and export of labour resources from China to Russia, as well as China’s receipt of additional sales channels for the confidently growing sales markets for consumer goods and sources of raw materials and primary products. The interaction of Russian regions with neighbouring provinces on the border with China not only preserves the raw material orientation of these regions, but also hinders the development and strengthening of the manufacturing industry in the structure of their regional economies, since border interaction for Russian regions immobilizes those stages of value-added production observed in the very first stages. In general, for the Chinese provinces there is a similar problem associated with such exports to border regions that have common borders with Russia, which does not contribute to the diversification and structural development of the regional economies of the Chinese provinces. That is why building an effective mechanism for border interaction between Russia and China is a strategically important issue for both countries.


ASTONJADRO ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 30
Author(s):  
Muhamad Lutfi ◽  
Nurul Chayati ◽  
Asrul Adriansyah

<p>Mosques serve as a place of worship and foster Muslims who live around the mosque, so the function of this can give a positive impact for Muslims’ life. Mosques also function as a place for developing people’s activities from the time of Prophet Muhammad to the present. It certainly plays important roles so the condition of the mosque, especially the interior, needs to have comfort element in order to get more solemnity when carrying out those activities. Mosque Al-Hidayah is located in Kampung Belentuk RT 001 RW 001, Kelurahan Cimahpar, Kecamatan Bogor Utara, Kota Bogor. This Belentuk village area has a land area of 23 hectares with a Muslim population of 1571 and 807 of them are men. This village has three mosques which Masjid Al-Hidayah is one of them. At this time, mosque Al-Hidayah has land area of 339 m<sup>2</sup> with a building area of 128,9 m<sup>2</sup> so that the room capacity can only accommodate 106 people. The number of men of Kampun Belantuk are divided into those three mosques of the village, even so, Mosque Al-Hidayah is not able to accommodate the number of people especially on Friday prayer because the number of worshipers is more than the current capacity of the mosque. The result of the analysis shows the need for prayer space is 330 m2 to accommodate 270 worshipers in prayer activities, especially Friday prayers, then the result of the analysis of the existing concrete structure were carried out by means of a concrete bounce test using the Hammer test, it is known that the average value of the concrete quality in the column is fc'=13.34 MPa, the block is equal to fc'=14.41 MPa. It indicates that the quality of the existing concrete of the Al-Hidayah Mosque does not meet the requirements of SNI 2847-2019 Article 19.2 concerning the minimum allowable normal concrete quality, then the design is carried out according to space requirements and a structural analysis is carried out on the planned design. The planned design is based on the existing space and land requirements which are 15 m x 14 m with a height of 3.5 m per floor and structural analysis is declared safe.</p>


2021 ◽  
Author(s):  
Jules D. P. Valentin ◽  
Hervé Straub ◽  
Franziska Pietsch ◽  
Marion Lemare ◽  
Christian H. Ahrens ◽  
...  

AbstractPseudomonas aeruginosa biofilms exhibit an intrinsic resistance to antibiotics and constitute a considerable clinical threat. In cystic fibrosis, a common feature of biofilms formed by P. aeruginosa in the airway is the occurrence of mutants deficient in flagellar motility. This study investigates the impact of flagellum deletion on the structure and antibiotic tolerance of P. aeruginosa biofilms, and highlights a role for the flagellum in adaptation and cell survival during biofilm development. Mutations in the flagellar hook protein FlgE influence greatly P. aeruginosa biofilm structuring and antibiotic tolerance. Phenotypic analysis of the flgE knockout mutant compared to the wild type (WT) reveal increased fitness under planktonic conditions, reduced initial adhesion but enhanced formation of microcolony aggregates in a microfluidic environment, and decreased expression of genes involved in exopolysaccharide formation. Biofilm cells of the flgE knock-out mutant display enhanced tolerance towards multiple antibiotics, whereas its planktonic cells show similar resistance to the WT. Confocal microscopy of biofilms demonstrates that gentamicin does not affect the viability of cells located in the inner part of the flgE knock-out mutant biofilms due to reduced penetration. These findings suggest that deficiency in flagellar proteins like FlgE in biofilms and in cystic fibrosis infections represent phenotypic and evolutionary adaptations that alter the structure of P. aeruginosa biofilms conferring increased antibiotic tolerance.


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