Immunopharmacological Activities of Muramyl Dipeptide, A Synthetic Mycobacterial Analog

1979 ◽  
pp. 187-196
Author(s):  
L. Chedid
Keyword(s):  
Muramyl Dipeptide

Muramyl-dipeptide analogues: Synthesis and biological activities

1988 ◽  
Vol 53 (11) ◽  
pp. 2897-2906 ◽  
Author(s):  
Jan Ježek ◽  
Milan Zaoral ◽  
Miloš Buděšínský ◽  
Jiří Günther ◽  
Jiří Rotta
Keyword(s):  
Biological Activities ◽  
Muramyl Dipeptide ◽  
Delayed Hypersensitivity ◽  
Test Compound ◽  
Active Compounds ◽  
Dipeptide Analogues ◽  
Pyrogenic Activity

In the search for immunoadjuvant active compounds without pyrogenic activity we prepared N-Ac-norMur-L-Abu-D-Gln-O-Bu (V), N-Ac-Mur-L-Abu-D-Gln-O-Bu (VII) and their respective α-benzylglycosides VI and VIII. All the prepared compounds are nonpyrogenic. In the delayed hypersensitivity test, compound V is inactive, VI is comparable to MDP, VII is more and VIII is less active than MDP.

Designed leucine‐rich repeat proteins bind two muramyl dipeptide ligands

2021 ◽  
Author(s):  
Christina S. Kim ◽  
Anne M. Brown ◽  
Tijana Z. Grove ◽  
Felicia A. Etzkorn
Keyword(s):  
Muramyl Dipeptide ◽  
Leucine Rich Repeat ◽  
Repeat Proteins

Immunomodulating activity of new muramyl dipeptide derivatives in vitro

1992 ◽  
Vol 114 (6) ◽  
pp. 1838-1841
Author(s):  
A. �. Medvedev ◽  
B. B. Fuks ◽  
N. V. Bovin ◽  
A. E. Zemlyakov
Keyword(s):  
Muramyl Dipeptide ◽  
Immunomodulating Activity ◽  
Muramyl Dipeptide Derivatives

Activation of mouse macrophages by muramyl dipeptide coupled with an anti-macrophage monoclonal antibody

1992 ◽  
Vol 3 (2) ◽  
pp. 194-199 ◽  
Author(s):  
Patrick Midoux ◽  
Anne Martin ◽  
Brigitte Collet ◽  
Michel Monsigny ◽  
Annie Claude Roche ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Muramyl Dipeptide ◽  
Mouse Macrophages

scholarly journals Ex vivo response to mucosal bacteria and muramyl dipeptide in inflammatory bowel disease

2016 ◽  
Vol 22 (44) ◽  
pp. 9734
Author(s):  
Claudia Loganes ◽  
Erica Valencic ◽  
Alessia Pin ◽  
Elisa Marini ◽  
Stefano Martelossi ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Ex Vivo ◽  
Muramyl Dipeptide ◽  
Inflammatory Bowel

The augmentation of tumor-specific immunity using haptenic muramyl dipeptide (MDP) derivatives

1985 ◽  
Vol 20 (3) ◽  
Author(s):  
Toshiyuki Hamaoka ◽  
Yasuyuki Takai ◽  
Atsushi Kosugi ◽  
Yumiko Mizushima ◽  
Junko Shima ◽  
...  
Keyword(s):  
Muramyl Dipeptide ◽  
Specific Immunity
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