Dynamic Tissue Remodeling in Chronic Liver Diseases: Abnormal Proliferation and Differentiation of Hepatocytes and Bile Ducts/Ductules

2018 ◽  
pp. 179-209
Author(s):  
Yuji Nishikawa
Keyword(s):  
Liver Diseases ◽  
Bile Ducts ◽  
Tissue Remodeling ◽  
Chronic Liver ◽  
Chronic Liver Diseases ◽  
Proliferation And Differentiation

scholarly journals Interactions between Myc and Mediators of Inflammation in Chronic Liver Diseases

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Ting Liu ◽  
Yu Zhou ◽  
Kwang Suk Ko ◽  
Heping Yang
Keyword(s):  
Inflammatory Mediators ◽  
Liver Diseases ◽  
Therapeutic Potential ◽  
Current Knowledge ◽  
Chronic Liver ◽  
Chronic Liver Diseases ◽  
Cellular Events ◽  
Mediators Of Inflammation ◽  
Proliferation And Differentiation ◽  
Inflammatory Processes

Most chronic liver diseases (CLDs) are characterized by inflammatory processes with aberrant expressions of various pro- and anti-inflammatory mediators in the liver. These mediators are the driving force of many inflammatory liver disorders, which often result in fibrosis, cirrhosis, and liver tumorigenesis. c-Myc is involved in many cellular events such as cell growth, proliferation, and differentiation. c-Myc upregulates IL-8, IL-10, TNF-α, and TGF-β, while IL-1, IL-2, IL-4, TNF-α, and TGF-βpromote c-Myc expression. Their interactions play a central role in fibrosis, cirrhosis, and liver cancer. Molecular interference of their interactions offers possible therapeutic potential for CLDs. In this review, current knowledge of the molecular interactions between c-Myc and various well known inflammatory mediators is discussed.

Helicobacter infection in patients with HCV-chronic liver diseases

2001 ◽  
Vol 120 (5) ◽  
pp. A725-A725
Author(s):  
M DORE ◽  
G REALDI ◽  
D MURA ◽  
D GRAHAM ◽  
A SEPULVEDA
Keyword(s):  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Diseases

TRAF1-C5as risk locus for increased hepatic fibrosis in chronic liver diseases

2008 ◽  
Vol 46 (09) ◽  
Author(s):  
F Grünhage ◽  
A Höblinger ◽  
S Schwartz ◽  
T Sauerbruch ◽  
F Lammert
Keyword(s):  
Hepatic Fibrosis ◽  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Diseases ◽  
Risk Locus

Targeting TGF-β2 in chronic liver diseases

2015 ◽  
Vol 53 (01) ◽  
Author(s):  
A Dropmann ◽  
H Korhonen ◽  
F Jaschinski ◽  
M Janicot ◽  
N Meindl-Beinker ◽  
...  
Keyword(s):  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Diseases

Role of scavenger receptors in the pathophysiology of chronic liver diseases

2013 ◽  
Author(s):  
Carolina Armengol ◽  
Ramon Bartoli ◽  
Lucia Sanjurjo ◽  
Isabel Serra ◽  
Nuria Amezaga ◽  
...  
Keyword(s):  
Liver Diseases ◽  
Chronic Liver ◽  
Scavenger Receptors ◽  
Chronic Liver Diseases

The Connection between Hypercoagulability and Fibrogenesis in Chronic Liver Diseases

2020 ◽  
Vol 25 (5) ◽  
pp. 1851-1860
Author(s):  
ROMEO-GABRIEL MIHĂILĂ ◽  
◽  
ADRIAN BOICEAN ◽  
VICTORIA BÎRLUȚIU
Keyword(s):  
Liver Diseases ◽  
Chronic Liver ◽  
Chronic Liver Diseases
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