Growth factors and guided bone regeneration

2020 ◽  
pp. 133-143
Author(s):  
Fawad Javed ◽  
Zohaib Akram ◽  
Junad Khan ◽  
Muhammad Sohail Zafar
2020 ◽  
Vol 7 (3) ◽  
pp. 313-320
Author(s):  
Yan Dai ◽  
Xiao-Hui Han ◽  
Li-Hua Hu ◽  
Hai-Wei Wu ◽  
Sheng-Yun Huang ◽  
...  

Abstract To evaluate the clinical efficacy of concentrated growth factors (CGFs) combined with mineralized collagen (MC) in guided bone regeneration (GBR). A retrospective study involving 29 patients treated with GBR technique, which was performed either CGF and MC complexes or MC alone. Implants were inserted simultaneously and cone-beam computed tomography was taken immediately, at 3 and 6 months postoperation. Questionnaires were completed by all patients so as to evaluate the main symptoms and daily activities during the first week after surgery. The outcomes of the two groups were statistically compared. All implants healed uneventfully. Patients in both groups suffered from different levels of discomfort for the reason of swelling, pain and chewing impairment on 1–2 days. Meanwhile, swelling of the Trial group was weaker than the Control group. When compared with the Control group, pain levels in Trial group were more rapidly reduced and patients took fewer analgesics from Day 3. Furthermore, the reconstitution mean value of the graft was thicker at 3 and 6 months in Trial group. CGFs complex with MC were beneficial to relieve the clinical symptoms, promote the peri-implant bone regeneration and shorten the healing time.


2019 ◽  
Vol 6 (4) ◽  
pp. 244-249
Author(s):  
Harjit Singh Sehgal ◽  
Steven D. Hokett ◽  
James A. Katancik

2015 ◽  
Vol 61 (4) ◽  
pp. 271-276
Author(s):  
Alexandra Mihaela Tuţă ◽  
◽  
Valentin Daniel Sîrbu ◽  
Ioan Sîrbu ◽  
Ştefan Nichita ◽  
...  

Dental implant therapy based on osseointegration has known a big expansion in dentistry in the last years. Dental implant rehabilitation is a common procedure in restoring partial or total edentulous pacients in our days. A problem regarding implant rehabilitation appears when the pacient doesn’t have enought bone to allow implant insertion in safety conditions. In this cases the clinician has to turn to complementary interventions in order to improve bone width and height so that implants could be inserted. One of the most known procedures is guided bone regeneration (GBR – guided bone regeneration) wich consists in placing a membrane to the bone defects. Platelet rich fibrin (PRF – platelet rich fibrin) is a second generation platelet concentrate wich gives the clinician access to growth factors throught a simple and up to date technology. These growth factors wich are autologous, non-toxic and non-immunogenic enhance and accelerate normal bone regeneration pathways. (1)


Author(s):  
Saurabh Mohan Kamat ◽  
Rakshit Khandeparker ◽  
Francis Akkara ◽  
Vikas Dhupar ◽  
Ashwin Mysore

Membrane fixation in guided bone regeneration (GBR) has been traditionally achieved using resorbable pins, titanium tacks or miniscrews. However, these techniques are marredwith a number of clinical challenges. This article presents the “SauFRa” technique, a novel technique for stabilization of resorbable membranes in both, single as well as multiple implant sites while avoiding the shortcomings of other suturing techniques described in literature. Furthermore, the technique also eliminates the possibility of complications observed when using resorbable pins, titanium tacks or miniscrews, such as damage to adjacent roots during insertion. The authors’ employed this technique in 89 patients (51 male and 35 female) and found no complications like tissue dehiscence, infection or graft migration.


2016 ◽  
Vol 1 (45) ◽  
Author(s):  
Bruno Pires Miranda

Resumo O osso é um tecido conjuntivo especializado, vascularizado e dinâmico que se modifica ao longo do organismo. Quando lesado, possui uma capacidade única de regeneração e reparação sem a presença de cicatrizes, mas em algumas situações devido tamanho do defeito ósseo não se regenera por completo. Assim, se faz necessária a realização de procedimentos de regeneração óssea guiada. Para isso, o implantodontista deve conhecer as bases biológicas da regeneração óssea guiada alveolar e suas indicações. Nesta revisão foram abordadas indicações, vantagens e tipos de biomateriais utilizados para preenchimento do alvéolo dentário imediatamente após a extração dentária sempre que o objetivo for à reabilitação através da instalação de implantes. Mesmo este, biomateriais, apresentando inúmeras qualidades, estudos ainda devem ser feitos a fim de obter a cada dia, um material sintético compatível com o tecido ósseo perdido em quantidades adequadas sem necessitar de cirurgias extra-bucais.ABSTRACT Bone is a specialized vascularized connective tissue that dynamic changes throughout the body. When injured, it has a unique ability to regenerate and repair without the presence of scars, but in some situations due to size of the bone defect does not regenerate completely. Thus, it is necessary to perform guided bone regeneration procedures. For this, the implant dentistry must know the biological bases of alveolar guided bone regeneration and its indications. In this review were addressed indications, advantages and types of biomaterials used for filling the tooth socket immediately after the tooth extraction whenever the goal is rehabilitation through implants installation. Even this, biomaterials, having several qualities, further studies must be done to obtain each day, a synthetic material compatible with the bone tissue lost in proper amounts without the need of extra-oral surgery.


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