Ankle-Brachial Index Test

2022 ◽  
pp. 40-43
Author(s):  
Jonathan S Ruan ◽  
Kimberly E. Ng
Keyword(s):  
Ankle Brachial Index ◽  
Index Test

Abstract 17730: The Appropriate Biomarker of a Cardiac Rehabilitation in the Patients With Post Abdominal Aortic Aneurysm Repair

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Atsuko Nakayama ◽  
Masatoshi Nagayama ◽  
Hiroyuki Morita ◽  
Issei Komuro
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Blood Culture ◽  
Cardiac Rehabilitation ◽  
Cardiopulmonary Exercise Testing ◽  
Ankle Brachial Index ◽  
Index Test ◽  
Cardiac Events ◽  
Roc Curve Analysis ◽  
Abdominal Aortic

Introduction: The useful biomarkers of cardiac rehabilitation after post cardiovascular surgery are still unknown. This is the first report describing the markers of the effect of cardiac rehabilitation on prognosis after abdominal aortic aneurysm (AAA) surgery. Methods: We conducted an observed cohort study on 1330 patients receiving surgical repair of AAA in the multicenter in Tokyo from January 2003 to December 2014. The patients who had cardiac rehabilitation more than once a week for more than 3 months after surgery were classified into rehabilitation group. The patients in rehabilitation group underwent cardiopulmonary exercise testing (CPX) before and 3 months after surgery. Total 274 inspection items including blood culture, computerized tomography, carotid duplex, ankle-brachial index test, cardiac echography, respiratory function test and CPX were cyclopaedically analyzed. The results of blood culture in rehabilitation group were compared to those in non-rehabilitaion group before surgery, 14 days after and 30days after surgery. Results: The average age of patients was 73±8 years and the average follow-up period was 2.5±2.2 years. The 355 patients had cardiac rehabilitation after AAA repair, and the other 975 patients did not. Basal characteristics including age, gender, hypertension, dyslipidemia, diabetes, smoking and drugs were statistically similar in both groups. The predictors of the risk of major adverse cardiac events (MACE) after surgery were co-existence of coronary artery disease, non-intake of beta-blockers, non-intake of ARBs and nonparticipation in cardiac rehabilitation. The ROC curve analysis of the markers demonstrated no remarkable marker for the risk of MACE after surgery. But the level of CRP in rehabilitation group was lower 14 days and 30 days after surgery compared to which in non-rehabilitation group (4.5 ± 4.3 mg/dl vs. 5.9 ± 6.5 mg/dl, p<0.001 and 4.2 ± 4.5 mg/dl vs. 6.5 ± 6.0 mg/dl, p<0.001), although the level of CRP was similar in both groups before surgery. Conclusions: Cardiac rehabilitation in patients after AAA surgery improved the risk of MACE, and especially CRP may be useful as a convenient marker of effective rehabilitation for secondary prevention of arteriosclerosis.

scholarly journals Association between frailty and peripheral arterial disease

2020 ◽  
Vol 19 (2) ◽  
pp. 124
Author(s):  
Sérgio Ribeiro Barbosa ◽  
Natália Rodrigues Dos Reis ◽  
Henrique Novais Mansur
Keyword(s):  
Peripheral Arterial Disease ◽  
Descriptive Analysis ◽  
Ankle Brachial Index ◽  
Female Gender ◽  
Arterial Disease ◽  
Sociodemographic Factors ◽  
Genetic Alterations ◽  
Index Test ◽  
Peripheral Arterial ◽  
The Relationship

Background: Frailty has been associated with lifestyle, chronic diseases, and genetic alterations and with high levels of proinflammatory proteins, justifying the relationship proposed by the emerging literature that seeks associations between frailty and cardiovascular diseases. Objective: To investigate clinical and sociodemographic factors associated with frailty, emphasizing the relationship with peripheral arterial disease. Methods: Medical records of 76 patients were analyzed, considering the results of the ankle-brachial index test, fragility, sociodemographic and clinical variables. After the descriptive analysis, differences between groups were tested by chi-square test, student’s t-test and Tukey's post hoc test, when they were appropriated. The value of p < 0.05 for statistically significant differences was considered. Results: The prevalence of frailty in the study sample was 22.3%, and 47.3% for pre-frail. Frailty was associated with female gender, hypertension, dyslipidemia and level of education. Changes in ankle-brachial index test were statistically associated with frailty. Conclusion: The results of this research show the necessary targeted efforts to prevent and treat frailty.Keywords: peripheral arterial disease, cardiovascular disease, chronic disease, fragility.

scholarly journals 4281 Developing a predictive tool to detect peripheral artery disease (PAD): Examining patient-reported symptoms in ischemic versus non-ischemic conditions (PREDICT PAD)

2020 ◽  
Vol 4 (s1) ◽  
pp. 27-27
Author(s):  
Rebecca Brown ◽  
Erica Schorr ◽  
Diane Treat-Jacobson
Keyword(s):  
Diagnostic Accuracy ◽  
De Novo ◽  
Ankle Brachial Index ◽  
Disease Patient ◽  
Index Test ◽  
Predictive Tool ◽  
Patient Reported ◽  
Artery Disease ◽  
Chi Square Analysis ◽  
Cardinal Symptom

OBJECTIVES/GOALS: Objectives: The study goal is to identify discriminating symptom characteristics of PAD versus non-ischemic conditions to improve recognition. Just as nausea, back, and jaw pain were once thought to be unrelated to myocardial infarction and coronary artery disease, patient-reported symptoms of PAD are frequently overlooked as being a sign of PAD. METHODS/STUDY POPULATION: Methods: Using a prospective de novo population-based cross-sectional design we will link symptom descriptors to PAD disease status using diagnostic testing in individuals who report lower extremity or buttock symptoms (n = 100). Symptom descriptors will be obtained via questionnaires and structured interviews will be completed pre and post physical function tests. Using near infrared spectroscopy, we will measure calf muscle tissue oxygenation levels to further differentiate ischemic vs. non-ischemic symptoms during exercise. The primary outcome will be the diagnostic accuracy of patient-reported symptoms which discriminate between PAD and non-PAD conditions. Positive predictive value and accuracy will be calculated using receiver operating characteristic (ROC) curve and chi-square analysis. RESULTS/ANTICIPATED RESULTS: Results: Previous studies from which symptom descriptors have been obtained were from patients with known PAD, of which 85-88% of participants were male.1–2 Seventy-six percent of this sample thus far is female. Nationally, PAD prevalence is 20% in those over the age of 70 years, however 58% of our study participants tested positive for PAD (via ankle brachial index test).3 The most commonly reported symptoms of PAD are “numbness” and “aching” vs. those without PAD most commonly reporting “cramping”. These results trend against our current understanding of PAD symptomatology, which is that cramping is the cardinal symptom of PAD.4 Preliminary analysis suggests that balance is a sensitive and specific predictor of PAD. Recruitment is ongoing, therefore results are preliminary. DISCUSSION/SIGNIFICANCE OF IMPACT: Translation of the results will impact primary care and community health. Improved disease detection will position providers to refer patients to exercise therapy before symptoms become disabling. Understanding the diagnostic accuracy of symptoms prepares us to apply novel techniques, such as statistical modeling, to systematically predict PAD.

How to perform the ankle brachial index test in clinical practice

2017 ◽  
Vol 207 (2) ◽  
pp. 60-61
Author(s):  
Nicole M Organ ◽  
Catherine Harrison
Keyword(s):  
Clinical Practice ◽  
Ankle Brachial Index ◽  
Index Test

Abstract 322: Cost Effectiveness Analysis of Peripheral Arterial Disease Screening With the Ankle-Brachial Index Test

2017 ◽  
Vol 37 (suppl_1) ◽  
Author(s):  
Nathan K Itoga ◽  
Hataka Minami ◽  
Meena Chelvakumar ◽  
Keon Pearson ◽  
Matthew W Mell ◽  
...  
Keyword(s):  
Cost Effectiveness ◽  
Incremental Cost ◽  
Medical Therapy ◽  
Medication Compliance ◽  
Ankle Brachial Index ◽  
Cost Effective ◽  
Arterial Disease ◽  
Index Test ◽  
Life Years ◽  
Peripheral Arterial

Introduction: Screening for asymptomatic PAD (aPAD) with the ankle-brachial index (ABI) test may reduce mortality and disease progression by identifying individuals who may benefit from early initiation of cardiovascular (CV) risk reduction therapies. Methods: Using a Markov model, we evaluated the cost-effectiveness of initiating medical therapy (e.g. statin & ACE-inhibitor) after a positive ABI screen in adults 65-years old. We modeled progression to symptomatic PAD (sPAD) and CV mortality with and without screening evaluating quality adjust life years (QALY). Cost of the ABI test, physician visit, new medication, and surgery for sPAD were calculated. Our baseline model estimated 96% of patients already eligible for medical therapy given the similar risk factor profiles of aPAD and CV disease. Repeated screening was considered given the imperfect screening test, development of disease with age, and opportunity to re-initiate therapy given limited medication compliance. Variables with uncertainty underwent a tornado analysis to determine variables with large effects. Results: Our model found an incremental cost of $367 and incremental QALY of 0.0022 with one-time ABI screening resulting in an incremental cost-effectiveness ratio (ICER) of $169,025/QALY over a 35-year period. Removing the benefits of medication on CV mortality increases the ICER by 51%, and removing the benefits of medication on PAD progression increases the ICER by 16%. A tornado diagram shows variables affecting the ICER (Figure). Screening high-risk populations, such as tobacco users where the prevalence of PAD may be 2.5x higher than the general population of 9%, decreases the ICER to $63,500/QALY. Conclusions: Our cost-effective analysis predicts that one-time ABI screening does not meet generally accepted thresholds for cost effectiveness. Disease prevalence and medication adherence had the largest effects on the ICER and are important to consider in implementing ABI screening.

scholarly journals COST-EFFECTIVENESS OF CARDIOVASCULAR RISK CLASSIFICATION BASED ON ANKLE-BRACHIAL INDEX TEST IN ASSOCIATION TO FRAMINGHAM RISK SCORE

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e274
Author(s):  
Alessandro Maloberti ◽  
Paolo Cortesi ◽  
M. Micale ◽  
G. Mazzaglia ◽  
Lucia Occhi ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Cost Effectiveness ◽  
Risk Score ◽  
Framingham Risk Score ◽  
Ankle Brachial Index ◽  
Risk Classification ◽  
Index Test ◽  
Framingham Risk

scholarly journals A multi centric study of diabetic foot ulcer: causes and complications

2019 ◽  
Vol 6 (4) ◽  
pp. 1327 ◽  
Author(s):  
Earnest Daniel Prasad Pilla ◽  
Rajendra Desai ◽  
Prashant Ramdas Kokiwar
Keyword(s):  
Diabetes Mellitus ◽  
Diabetic Foot ◽  
Ankle Brachial Index ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Ulcer Formation ◽  
Index Test ◽  
Ischemic Ulcer ◽  
Plantar Aspect ◽  
The Right

Background: Diabetes mellitus is a metabolic disorder and has become an epidemic. 73 million people in India have diabetes mellitus. Presently India has ranked the second highest country with diabetics in the world. Diabetic foot ulcer is a result of one or both of the complications of diabetes such as neuropathy and ischemia. The objective of the study was to study the causes for the ulcer formation on the toes.Methods: A prospective study was carried out from January 2016 to August 2018 from multiple diabetic clinics in Hyderabad, India. All the patients had undergone the following tests. 1) X-ray foot, 2) ABI (ankle brachial index) test, 3) Neuropathy test by VPT (vibration perception test) and monofilament.Results: The age of the patients mostly ranged from 50 to 70 years. 61% of the patients had neuropathic ulcer, 20% had ischemic ulcer, 19% had neuro-ischemic ulcer. 69% of these patients had osteomyelitis. 52% had ulcer on the right foot and 48% on the left. 15% had dry gangrene with ulcer where as 85% had infected ulcers. 60% of the ulcers were only on the plantar aspect and 24% had ulcers all around the toe. ABI (ankle brachial index) was normal 0.9 to 1.2 in 80% of patients whereas 20% had abnormal (<0.9). 60% of patients had ulcers involving the 1st and 2nd toes and both feet were almost equally affected.Conclusions: Neuropathy is the leading cause for ulcers on the toes followed by ischemia and then infection. Treating the neuropathic ulcer early can bring down the amputation rate of the toes by 50%.

Sign in / Sign up

Export Citation Format

Share Document