Coupling of the ring-oven-based preconcentration technique and surface-enhanced Raman spectroscopy: Application for the determination of purine bases in DNA

2017 ◽  
Vol 991 ◽  
pp. 95-103 ◽  
Author(s):  
Javier E.L. Villa ◽  
Celio Pasquini ◽  
Ronei J. Poppi
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Purine Bases ◽  
Ring Oven ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Preconcentration Technique

Multivariate Analysis Aided Surface-Enhanced Raman Spectroscopy (MVA-SERS) Multiplex Quantitative Detection of Trace Fentanyl in Illicit Drug Mixtures Using a Handheld Raman Spectrometer

2021 ◽  
pp. 000370282110329
Author(s):  
Ling Wang ◽  
Mario O. Vendrell-Dones ◽  
Chiara Deriu ◽  
Sevde Doğruer ◽  
Peter de B. Harrington ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Principal Component ◽  
Surface Enhanced Raman Spectroscopy ◽  
Quantitative Detection ◽  
Least Squares Regression ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Current Screening

Recently there has been upsurge in reports that illicit seizures of cocaine and heroin have been adulterated with fentanyl. Surface-enhanced Raman spectroscopy (SERS) provides a useful alternative to current screening procedures that permits detection of trace levels of fentanyl in mixtures. Samples are solubilized and allowed to interact with aggregated colloidal nanostars to produce a rapid and sensitive assay. In this study, we present the quantitative determination of fentanyl in heroin and cocaine using SERS, using a point-and-shoot handheld Raman system. Our protocol is optimized to detect pure fentanyl down to 0.20 ± 0.06 ng/mL and can also distinguish pure cocaine and heroin at ng/mL levels. Multiplex analysis of mixtures is enabled by combining SERS detection with principal component analysis and super partial least squares regression discriminate analysis (SPLS-DA), which allow for the determination of fentanyl as low as 0.05% in simulated seized heroin and 0.10% in simulated seized cocaine samples.

scholarly journals Rapid Determination of Thiabendazole Pesticides in Rape by Surface Enhanced Raman Spectroscopy

Sensors ◽  
2018 ◽  
Vol 18 (4) ◽  
pp. 1082 ◽  
Author(s):  
Lei Lin ◽  
Tao Dong ◽  
Pengcheng Nie ◽  
Fangfang Qu ◽  
Yong He ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Rapid Determination ◽  
Surface Enhanced Raman Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman
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