Recent advances in DNA walker machines and their applications coupled with signal amplification strategies: A critical review

2021 ◽  
pp. 338523
Author(s):  
Mingdi Xu ◽  
Dianping Tang
2021 ◽  
Author(s):  
Soumi Dutta ◽  
Bramha Gupta ◽  
suneel Kumar srivastava ◽  
Ashok Kumar Gupta

The rapid increase of toxic dye wastewater generated from various industries remains a severe public health problem and of prime environmental protection concern. Therefore, it has imposed a major challenge...


The Analyst ◽  
2021 ◽  
Author(s):  
Na Wang ◽  
Yong Jian Jiang ◽  
Xu Zhang ◽  
Hua Rong Lin ◽  
Feng Cheng ◽  
...  

An Exo III-propelled stochastic 3D DNA walker based on nanosurface energy transfer was developed for enzyme-assisted DNA detection with signal amplification.


2020 ◽  
Vol 5 (1) ◽  
pp. 49-66 ◽  
Author(s):  
Léonard Bezinge ◽  
Akkapol Suea-Ngam ◽  
Andrew J. deMello ◽  
Chih-Jen Shih

This account reviews the major amplification strategies utilizing nanomaterials in electrochemical biosensing for robust and sensitive molecular diagnostics.


Author(s):  
Albano N. Carneiro Neto ◽  
Ercules E.S. Teotonio ◽  
Gilberto F. de Sá ◽  
Hermi F. Brito ◽  
Janina Legendziewicz ◽  
...  

Molecules ◽  
2020 ◽  
Vol 25 (15) ◽  
pp. 3542
Author(s):  
Sebastian Cajigas ◽  
Jahir Orozco

Nanobioconjugates are hybrid materials that result from the coalescence of biomolecules and nanomaterials. They have emerged as a strategy to amplify the signal response in the biosensor field with the potential to enhance the sensitivity and detection limits of analytical assays. This critical review collects a myriad of strategies for the development of nanobioconjugates based on the conjugation of proteins, antibodies, carbohydrates, and DNA/RNA with noble metals, quantum dots, carbon- and magnetic-based nanomaterials, polymers, and complexes. It first discusses nanobioconjugates assembly and characterization to focus on the strategies to amplify a biorecognition event in biosensing, including molecular-, enzymatic-, and electroactive complex-based approaches. It provides some examples, current challenges, and future perspectives of nanobioconjugates for the amplification of signals in electrochemical biosensing.


2020 ◽  
Vol 56 (14) ◽  
pp. 2135-2138 ◽  
Author(s):  
Xue-Jiao Yang ◽  
Mei-Rong Cui ◽  
Xiang-Ling Li ◽  
Hong-Yuan Chen ◽  
Jing-Juan Xu

We construct a target-triggered, self-powered 3D DNA walker for achieving intracellular signal amplification and sensitive imaging analysis of microRNAs.


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