Genetic analyses of Trypanosoma cruzi isolates from naturally infected triatomines and humans in northeastern Brazil

The C. cerifera palm tree (carnaúba) is widely distributed in the Northeastem Brazil, including the State of Piauí. This investigation revealed that R. nasutus is the ortly triatomine species captured on that palm tree, in five different localities. 78% of palm trees were infested with triatomines, and 4.0% were infected with flagellates morphologically and biologically indistinguishable from Trypanosoma cruzi. Birds, rodents and marsupials were found as major blood meai sources for R. nasutus.

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Humoral and Cellular Immune Response of Adults from Northeastern Brazil with Chronic Trypanosoma cruzi Infection: Depressed Cellular Immune Response to T. cruzi Antigen among Chagas' Disease Patients with Symptomatic Versus Indeterminate Infection

American Journal of Tropical Medicine and Hygiene ◽

10.4269/ajtmh.1993.49.370 ◽

1993 ◽

Vol 49 (3) ◽

pp. 370-382 ◽

Cited By ~ 29

Author(s):

Martin S. Cetron ◽

Francisco P. Basilio ◽

Jose N. Paes ◽

Anastacio Q. Sousa ◽

Wesley C. Van Voorhis ◽

...

Keyword(s):

Immune Response ◽

Trypanosoma Cruzi ◽

Chagas Disease ◽

Cellular Immune Response ◽

Northeastern Brazil ◽

Cellular Immune ◽

Cruzi Infection

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Homogeneity of Trypanosoma cruzi I, II, and III populations and the overlap of wild and domestic transmission cycles by Triatoma brasiliensis in northeastern Brazil

Parasitology Research ◽

10.1007/s00436-013-3301-y ◽

2013 ◽

Vol 112 (4) ◽

pp. 1543-1550 ◽

Cited By ~ 12

Author(s):

Antonia Cláudia Jácome da Câmara ◽

Eliane Lages-Silva ◽

George Harisson Felinto Sampaio ◽

Daniella Alchaar D’Ávila ◽

Egler Chiari ◽

...

Keyword(s):

Trypanosoma Cruzi ◽

Northeastern Brazil ◽

Transmission Cycles

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Risk factors associated with seropositivity for Leishmania spp. and Trypanosoma cruzi in dogs in the state of Paraiba, Brazil

Revista Brasileira de Parasitologia Veterinária ◽

10.1590/s1984-29612016010 ◽

2016 ◽

Vol 25 (1) ◽

pp. 90-98 ◽

Cited By ~ 8

Author(s):

Annielle Regina da Fonseca Fernandes ◽

Carla Lauise Rodrigues Menezes Pimenta ◽

Ivana Fernandes Vidal ◽

Gabriela Capriogli Oliveira ◽

Raissa Saran Sartori ◽

...

Keyword(s):

Risk Factors ◽

Trypanosoma Cruzi ◽

Fluorescent Antibody ◽

Antibody Test ◽

The State ◽

Control Measures ◽

Northeastern Brazil ◽

Soil Cement ◽

Canine Population ◽

Leishmania Spp

Abstract The aim of this survey was to determine the seropositivity and risk factors forLeishmania spp. and Trypanosoma cruzi in dogs in the State of Paraíba, Northeastern Brazil. A total of 1,043 dogs were tested, and the serological diagnoses of Chagas disease (CD) and canine visceral leishmaniasis (CVL) was performed by the indirect fluorescent antibody test (IFAT). Animals that tested seropositive for both diseases (by IFAT) were further subjected to ELISA. Of the 1,043 dogs 81 (7.8%; 95% CI = 6.1-9.4%) tested seropositive for Leishmania spp., while 83 were seropositive for T. cruzi (7.9%; 95% CI = 6.3-9.6%). Simultaneous serological reactions were detected in 49 animals (4.6%; 95% CI= 3.6-6.2%). Semi-domiciled housing (OR = 2.044), free housing (OR = 4.151), and soil (OR = 3.425) and soil/cement (OR = 3.065) environmental conditions were identified as risk factors for CVL seropositivity. The risk factors identified for CD seropositivity were semi-domiciled (OR = 2.353) or free housing (OR = 3.454), and contact with bovine (OR = 2.015). This study revealed the presence of dogs in the Paraíba State seropositive for CVL and CD, suggesting the need for revisiting and intensification of disease control measures through constant monitoring of the canine population.

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Neolignans from plants in northeastern Brazil (Lauraceae) with activity against Trypanosoma cruzi

Experimental Parasitology ◽

10.1016/j.exppara.2009.11.007 ◽

2010 ◽

Vol 124 (3) ◽

pp. 319-324 ◽

Cited By ~ 27

Author(s):

M.M.O. Cabral ◽

J.M. Barbosa-Filho ◽

G.L.A. Maia ◽

M.C.O. Chaves ◽

M.V. Braga ◽

...

Keyword(s):

Trypanosoma Cruzi ◽

Northeastern Brazil

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Ecology of Triatoma brasiliensis in northeastern Brazil: seasonal distribution, feeding resources, and Trypanosoma cruzi infection in a sylvatic population

Journal of Vector Ecology ◽

10.1111/j.1948-7134.2010.00097.x ◽

2010 ◽

Vol 35 (2) ◽

pp. 385-394 ◽

Cited By ~ 23

Author(s):

Otilia Sarquis ◽

Filipe A. Carvalho-Costa ◽

Lívia Silva Oliveira ◽

Rosemere Duarte ◽

Paulo Sergio D′Andrea ◽

...

Keyword(s):

Trypanosoma Cruzi ◽

Seasonal Distribution ◽

Northeastern Brazil ◽

Feeding Resources ◽

Cruzi Infection

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Wide distribution of Trypanosoma cruzi-infected triatomines in the State of Bahia, Brazil

Parasites & Vectors ◽

10.1186/s13071-019-3849-1 ◽

2019 ◽

Vol 12 (1) ◽

Cited By ~ 2

Author(s):

Gilmar Ribeiro ◽

Carlos G. S. dos Santos ◽

Fernanda Lanza ◽

Jamylle Reis ◽

Fernanda Vaccarezza ◽

...

Keyword(s):

Spatial Analysis ◽

Trypanosoma Cruzi ◽

Potential Risk ◽

Blood Meal ◽

Species Complex ◽

Domestic Animals ◽

Wide Distribution ◽

The State ◽

Northeastern Brazil ◽

Epidemiologic Surveillance

Abstract Background The identification of Trypanosoma cruzi and blood-meal sources in synanthropic triatomines is important to assess the potential risk of Chagas disease transmission. We identified T. cruzi infection and blood-meal sources of triatomines caught in and around houses in the state of Bahia, northeastern Brazil, and mapped the occurrence of infected triatomines that fed on humans and domestic animals. Methods Triatominae bugs were manually captured by trained agents from the Epidemiologic Surveillance team of Bahia State Health Service between 2013 and 2014. We applied conventional PCR to detect T. cruzi and blood-meal sources (dog, cat, human and bird) in a randomized sample of triatomines. We mapped triatomine distribution and analyzed vector hotspots with kernel density spatial analysis. Results In total, 5906 triatomines comprising 15 species were collected from 127 out of 417 municipalities in Bahia. The molecular analyses of 695 triatomines revealed a ~10% T. cruzi infection rate, which was highest in the T. brasiliensis species complex. Most bugs were found to have fed on birds (74.2%), and other blood-meal sources included dogs (6%), cats (0.6%) and humans (1%). Trypanosoma cruzi-infected triatomines that fed on humans were detected inside houses. Spatial analysis showed a wide distribution of T. cruzi-infected triatomines throughout Bahia; triatomines that fed on dogs, humans, and cats were observed mainly in the northeast region. Conclusions Synanthropic triatomines have a wide distribution and maintain the potential risk of T. cruzi transmission to humans and domestic animals in Bahia. Ten species were recorded inside houses, mainly Triatoma sordida, T. pseudomaculata, and the T. brasiliensis species complex. Molecular and spatial analysis are useful to reveal T. cruzi infection and blood-meal sources in synanthropic triatomines, identifying areas with ongoing threat for parasite transmission and improving entomological surveillance strategies.

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