scholarly journals Proof of concept for eliminating Aedes aegypti production by means of integrated control including turtles, copepods, tilapia, and community participation in Monte Verde, Honduras

Acta Tropica ◽  
2021 ◽  
pp. 106269
Author(s):  
Gerald G. Marten ◽  
Xenia Caballero ◽  
Arnulfo Larios ◽  
Hilda Bendaña
Keyword(s):  
Aedes Aegypti ◽  
Community Participation ◽  
Integrated Control ◽  
Proof Of Concept ◽  
Monte Verde

scholarly journals A New Strategy for Aedes aegypti (Diptera: Culicidae) Control With Community Participation Using a New Fumigant Formulation

2011 ◽  
Vol 48 (3) ◽  
pp. 577-583 ◽  
Author(s):  
Laura Harburguer ◽  
Gastón Beltrán ◽  
Lucila Goldberg ◽  
Laura Goldberg ◽  
Eduardo Zerba ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Community Participation ◽  
New Strategy

Aedes aegypti population model with integrated control

2018 ◽  
Vol 12 (22) ◽  
pp. 1075-1083
Author(s):  
Julian A. Hernandez S. ◽  
John F. Arredondo M. ◽  
Anibal Munoz L. ◽  
Juan C. Jamboos T.
Keyword(s):  
Aedes Aegypti ◽  
Population Model ◽  
Integrated Control ◽  
Aegypti Population

scholarly journals Combined sterile insect technique and incompatible insect technique: The first proof-of-concept to suppress Aedes aegypti vector populations in semi-rural settings in Thailand

2019 ◽  
Vol 13 (10) ◽  
pp. e0007771 ◽  
Author(s):  
Pattamaporn Kittayapong ◽  
Suwannapa Ninphanomchai ◽  
Wanitch Limohpasmanee ◽  
Chitti Chansang ◽  
Uruyakorn Chansang ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Sterile Insect Technique ◽  
Proof Of Concept ◽  
Incompatible Insect Technique ◽  
Rural Settings

Eradication of Aedes aegypti from a village in Vietnam, using copepods and community participation.

1998 ◽  
Vol 59 (4) ◽  
pp. 657-660 ◽  
Author(s):  
S N Vu ◽  
T Y Nguyen ◽  
B H Kay ◽  
J W Reid ◽  
G G Marten
Keyword(s):  
Aedes Aegypti ◽  
Community Participation

scholarly journals Susceptibility of Aedes aegypti larvae to temephos and Bacillus thuringiensis var israelensis in integrated control

1991 ◽  
Vol 25 (3) ◽  
pp. 184-187 ◽  
Author(s):  
Carlos Fernando S. de Andrande ◽  
Maurício Modolo
Keyword(s):  
Bacillus Thuringiensis ◽  
Aedes Aegypti ◽  
Integrated Control ◽  
Integrated Treatment ◽  
Fourth Instar ◽  
Two Agents ◽  
Lethal Time ◽  
Third Instar Larvae

The susceptibility of field collected Aedes aegypti larvae was evaluated in terms of median lethal time (LT50) and final mortality, when treated with temephos, Bacillus thuringiensis var israelensis as well as mixtures of these two agents. Third instar larvae were shown to be more susceptible than early and late fourth instar ones to the entomopathogen. Survival of some individuals when exposed to temephos suggest possible resistance. Temporal synergism in early fourth instar larvae was detected when they were exposed to mixtures of Bti-temephos. The possibility of this integrated treatment is commented on.

scholarly journals Reduced competence to arboviruses following the sustainable invasion of Wolbachia into native Aedes aegypti from Southeastern Brazil

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
João Silveira Moledo Gesto ◽  
Gabriel Sylvestre Ribeiro ◽  
Marcele Neves Rocha ◽  
Fernando Braga Stehling Dias ◽  
Julia Peixoto ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Disease Transmission ◽  
Oral Feeding ◽  
Southeastern Brazil ◽  
Proof Of Concept ◽  
Small Community ◽  
High Infection ◽  
Promising Solution ◽  
Virus Blocking

AbstractField release of Wolbachia-infected Aedes aegypti has emerged as a promising solution to manage the transmission of dengue, Zika and chikungunya in endemic areas across the globe. Through an efficient self-dispersing mechanism, and the ability to induce virus-blocking properties, Wolbachia offers an unmatched potential to gradually modify wild Ae. aegypti populations turning them unsuitable disease vectors. Here we describe a proof-of-concept field trial carried out in a small community of Niterói, greater Rio de Janeiro, Brazil. Following the release of Wolbachia-infected eggs, we report here a successful invasion and long-term establishment of the bacterium across the territory, as denoted by stable high-infection indexes (> 80%). We have also demonstrated that refractoriness to dengue and Zika viruses, either thorough oral-feeding or intra-thoracic saliva challenging assays, was maintained over the adaptation to the natural environment of Southeastern Brazil. These findings further support Wolbachia’s ability to invade local Ae. aegypti populations and impair disease transmission, and will pave the way for future epidemiological and economic impact assessments.

scholarly journals Experimental Infection of Calves with Transfected Attenuated Babesia bovis Expressing the Rhipicephalus microplus Bm86 Antigen and eGFP Marker: Preliminary Studies towards a Dual Anti-Tick/Babesia Vaccine

Pathogens ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 135
Author(s):  
Monica L. Mazuz ◽  
Jacob M. Laughery ◽  
Benjamin Lebovitz ◽  
Daniel Yasur-Landau ◽  
Assael Rot ◽  
...  
Keyword(s):  
Integrated Control ◽  
Tick Control ◽  
Rhipicephalus Microplus ◽  
Control Measures ◽  
Babesia Bovis ◽  
Proof Of Concept ◽  
Bovine Babesiosis ◽  
Simultaneous Control ◽  
Tick Borne Disease ◽  
Vaccine Approach

Bovine babesiosis, caused by Babesia bovis and B. bigemina, is a major tick-borne disease of cattle with global economic impact. The disease can be prevented using integrated control measures including attenuated Babesia vaccines, babesicidal drugs, and tick control approaches. Vaccination of cattle with the Rhipicephalus microplus Bm86-based recombinant vaccine reduces the fitness of R. microplus and R. annulatus, but several booster inoculations are required to maintain protection. Herein, we generated a stable transfected strain of B. bovis expressing an enhanced GFP (eGFP) and a chimeric version of Bm86 (B. bovis/Bm86/eGFP). The eGFP was expressed in the parasite cytoplasm, whereas Bm86 was displayed on the surface of merozoites. Three splenectomized calves experimentally infected with B. bovis/Bm86/eGFP showed mild signs of acute disease and developed long-lasting antibody responses to B. bovis and native Bm86. No evidence of sequestration of parasites in the cerebral capillaries was found upon postmortem analysis, confirming attenuation of the strain. This is the first report of transfected B. bovis expressing the tick antigen Bm86 on the merozoite surface that elicits an antibody response to native Bm86. These results represent a proof of concept for a novel live, attenuated, tagged dual-vaccine approach to attempt simultaneous control of babesiosis and tick infestation.

scholarly journals Reduced competence to arboviruses following the sustainable invasion of Wolbachia into native Aedes aegypti from Niterói, Southeastern Brazil

2020 ◽  
Author(s):  
João Silveira Moledo Gesto ◽  
Gabriel Sylvestre Ribeiro ◽  
Marcele Neves Rocha ◽  
Fernando Braga Stehling Dias ◽  
Julia Peixoto ◽  
...  
Keyword(s):  
Aedes Aegypti ◽  
Disease Transmission ◽  
Oral Feeding ◽  
Southeastern Brazil ◽  
Proof Of Concept ◽  
Small Community ◽  
High Infection ◽  
Promising Solution ◽  
Virus Blocking

AbstractField release of Wolbachia-infected Aedes aegypti has emerged as a promising solution to manage the transmission of dengue, Zika and chikungunya in endemic areas across the globe. Through an efficient self-dispersing mechanism, and the ability to induce virus-blocking properties, Wolbachia offers an unmatched potential to gradually modify wild Ae. aegypti populations turning them unsuitable disease vectors. Here in this work, a proof-of-concept field trial was carried out in a small community of Niterói, greater Rio de Janeiro. Following the release of Wolbachia-infected eggs, we reported a successful invasion and long-term establishment of the bacterium across the territory, as denoted by stable high-infection indexes (>80%). We have also demonstrated that refractoriness to dengue and Zika viruses, either thorough oral-feeding or intra-thoracic saliva challenging assays, were maintained over the adaptation to the natural environment of Southeastern Brazil. These findings further support Wolbachia’s ability to invade local Ae. aegypti populations and impair disease transmission, and shall pave the way for future epidemiological and economic impact assessments.

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