Oxycodone induced euphoria in ED patients with acute musculoskeletal pain. A secondary analysis of data from a randomized trial

Adherence is a critical factor to consider when interpreting study results from randomized clinical trials (RCTs) comparing one diet to another, but it is frequently not reported by researchers. The purpose of this secondary analysis of the Keto–Med randomized trial was to provide a detailed examination and comparison of the adherence to the two study diets (Well Formulated Ketogenic Diet (WFKD) and Mediterranean Plus (Med-Plus)) under the two conditions: all food being provided (delivered) and all food being obtained by individual participants (self-provided). Diet was assessed at six time points including baseline (x1), week 4 of each phase when participants were receiving food deliveries (x2), week 12 of each phase when participants were preparing and providing food on their own (x2), and 12 weeks after participants completed both diet phases and were free to choose their own diet pattern (x1). The adherence scores for WFKD and Med-Plus were developed specifically for this study. Average adherence to the two diet patterns was very similar during both on-study time points of the intervention. Throughout the study, a wide range of adherence was observed among participants—for both diet types and during both the delivery phase and self-provided phase. Insight from this assessment of adherence may aid other researchers when answering the important question of how to improve behavioral adherence during dietary trials. This study is registered at clinicaltrials.gov NCT03810378.

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OC06.01: Vaginal progesterone and the risk of preterm delivery in high-risk twin gestations - secondary analysis of a placebo-controlled randomized trial

Ultrasound in Obstetrics and Gynecology ◽

10.1002/uog.9123 ◽

2011 ◽

Vol 38 (S1) ◽

pp. 11-11 ◽

Cited By ~ 4

Author(s):

K. Klein ◽

L. Rode ◽

K. Nicolaides ◽

E. Krampl-Bettelheim ◽

H. Larsen ◽

...

Keyword(s):

High Risk ◽

Randomized Trial ◽

Preterm Delivery ◽

Secondary Analysis ◽

Vaginal Progesterone

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Utilisation of pain counselling in osteopathic practice: secondary analysis of a nationally representative sample of Australian osteopaths

Scandinavian Journal of Pain ◽

10.1515/sjpain-2020-0058 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Kylie Fitzgerald ◽

Brett Vaughan ◽

Michael Fleischmann ◽

Shane Pritchard ◽

Jane Mulcahy ◽

...

Keyword(s):

Clinical Practice ◽

Musculoskeletal Pain ◽

Representative Sample ◽

Secondary Analysis ◽

Chronic Musculoskeletal Pain ◽

Guideline Recommendation ◽

Allied Health Professionals ◽

Practice Characteristics ◽

Nationally Representative ◽

Evidence Based Care

AbstractObjectivesAdvice, reassurance and education are recommended as first line treatments for musculoskeletal pain conditions such as low back pain. Osteopaths are registered primary contact allied health professionals in the Australian healthcare system who primarily manage acute and chronic musculoskeletal pain conditions. This study aimed to investigate the proportion of Australian osteopaths who do and do not utilise advice, reassurance and education (pain counselling) in their clinical practice, and determine the characteristics associated with the frequency of using pain counselling in clinical practice.MethodsA secondary analysis of practice characteristics from a nationally representative sample of Australian osteopaths was undertaken. Participants completed a 27-item practice characteristics questionnaire between July-December 2016. Bivariate analyses were used to identify significant variables for inclusion in a backward multiple logistic regression model. Adjusted odds ratios (OR) were calculated for significant variables.ResultsResponses were received from 991 Australian osteopaths, representing 49% of the profession. Of these 264 (26.64%) indicated often utilising pain counselling, and 727 (73.36%) reported not often utilising pain counselling. Those who utilised pain counselling were more than twice as likely to report research evidence had a high impact on their clinical practice (OR 2.11), and nearly twice as likely to discuss physical activity with their patients (OR 1.84).ConclusionsPain counselling is under-utilised by nearly three quarters of the Australian osteopathic profession as a management strategy. Future studies are required to explore the reasons why most in the profession comprised in this sample are infrequently utilising this guideline recommendation. Given the frequency of chronic musculoskeletal pain conditions presenting to Australian osteopaths, strategies appear to be needed to advance the profession via professional development in accessing and using evidence-based care for pain conditions.

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