The Impact of Mental Health Conditions on Oral Anticoagulation Therapy and Outcomes in Patients with Atrial Fibrillation: A Systematic Review and Meta-analysis

Abstract Background Peer support is being integrated within mental health services to further the development of a recovery approach. However, the most effective models and formats of intervention delivery are unknown. We conducted this systematic review and meta-analysis to determine the effectiveness of peer support for improving outcomes for people with lived experience of mental health conditions, when delivered as group interventions. Methods Studies reporting randomised controlled trials of group peer support interventions for people experiencing mental health conditions were identified by searching MEDLINE, PsycINFO, Embase and Cochrane CENTRAL, from inception until July 12th 2019 and undertaking supplementary searches. Included studies were assessed for risk of bias and meta-analyses were conducted if three or more trials provided usable data. Results Eight trials met eligibility criteria, providing data from 2131 participants. Six trials had either high or unclear risk of bias. Interventions were categorised as mutual support groups, or peer support groups, sub-categorised as anti-stigma or self-management interventions. Meta-analyses were only possible for peer support groups and five outcomes. We found evidence that group peer support may make small improvements to overall recovery but not hope or empowerment individually, or to clinical symptoms. Evidence for effectiveness for outcomes which could not be meta-analysed was mixed. Conclusions Findings from the few eligible trials suggest group peer support interventions may be specifically effective for supporting personal recovery and have a limited impact on other outcomes, though there were some risks of bias to study findings. Interventions were heterogeneous and most social outcomes were absent in the literature, highlighting further limitations to the current evidence-base. There is insufficient evidence available from trials of group peer support torecommend the routine implementation of these interventions across mainstream mental health services at present. More high-quality trials of peer-developed, group peer support interventions are needed in order tomake firm conclusions about intervention effectiveness.

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Data visualization in chronic neurological and mental health condition self-management: a systematic review of user perspectives (Preprint)

10.2196/preprints.25249 ◽

2020 ◽

Author(s):

Ashley Polhemus ◽

Jan Novak ◽

Shazmin Majid ◽

Sara Simblett ◽

Stuart Bruce ◽

...

Keyword(s):

Mental Health ◽

Systematic Review ◽

Data Visualization ◽

User Preferences ◽

Health Conditions ◽

Cochrane Library ◽

Mental Health Conditions ◽

Visualization Design ◽

The Impact ◽

Data Visualizations

BACKGROUND Remote measurement technology (RMT) such as mobile health devices and applications, are increasingly used by those living with chronic neurological and mental health conditions. RMT enables real-world data collection and regular feedback, providing users with insights about their own conditions. Data visualizations are an integral part of RMT, though little is known about visualization design preferences from the perspectives of those living with chronic conditions. OBJECTIVE Explore the experiences and preferences of individuals with chronic neurological and mental health conditions on data visualizations derived from RMT to manage health. METHODS In this systematic review, we searched peer-reviewed literature and conference proceedings (PubMed, IEEE Xplore, EMBASE, Web of Science, ACM Computer-Human Interface proceedings, and the Cochrane Library) for original articles published between January 2007 and February 2020 that reported perspectives on data visualization of people living with chronic neurological and mental health conditions. Two reviewers independently screened each abstract and full-text article, with disagreements resolved through discussion. Studies were critically appraised and extracted data underwent thematic synthesis. RESULTS We identified 28 eligible publications from 24 studies representing 11 conditions. Coded data coalesced into four themes: desire for data visualization, the impact of visualizations on condition management, visualizations as data reporting tools, and visualization design considerations. Data visualizations were viewed an integral part of users’ experiences with RMT, impacting satisfaction and engagement. However, user preferences were diverse and often conflicting, both between and within conditions. CONCLUSIONS When used effectively, data visualizations are valuable, engaging components of RMT. They can provide structure and insight, allowing individuals to manage their own health more effectively. However, visualizations are not “one-size-fits-all,” and it is important to engage with potential user during visualization design to understand when, how, and with whom the visualizations will be used to manage health.

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A systematic review of the impact of brief interventions on substance use and co-morbid physical and mental health conditions

Mental Health and Substance Use ◽

10.1080/17523281.2011.533449 ◽

2011 ◽

Vol 4 (1) ◽

pp. 38-61 ◽

Cited By ~ 12

Author(s):

Eileen F.S. Kaner ◽

Nicola Brown ◽

Katherine Jackson

Keyword(s):

Mental Health ◽

Systematic Review ◽

Substance Use ◽

Brief Interventions ◽

Health Conditions ◽

Physical And Mental Health ◽

Mental Health Conditions ◽

The Impact

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LEFT ATRIAL APPENDAGE CLOSURE IN PATIENTS WITH CONTRAINDICATIONS TO ORAL ANTICOAGULATION THERAPY: A SYSTEMATIC REVIEW AND POOLED META-ANALYSIS

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(19)30912-x ◽

2019 ◽

Vol 73 (9) ◽

pp. 304

Author(s):

Tawseef Dar ◽

Fnu Sibghat Tul Llah ◽

Bharath Yarlagadda ◽

Shady Abohashem ◽

Tarun Dahlia ◽

...

Keyword(s):

Systematic Review ◽

Oral Anticoagulation ◽

Left Atrial ◽

Left Atrial Appendage ◽

Meta Analysis ◽

Anticoagulation Therapy ◽

Atrial Appendage ◽

Left Atrial Appendage Closure ◽

Oral Anticoagulation Therapy

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Oral Anticoagulation Therapy in Heart Failure Patients in Sinus Rhythm: A Systematic Review and Meta-Analysis

PLoS ONE ◽

10.1371/journal.pone.0052952 ◽

2013 ◽

Vol 8 (1) ◽

pp. e52952 ◽

Cited By ~ 16

Author(s):

Giuseppe Rengo ◽

Gennaro Pagano ◽

Alessandro Squizzato ◽

Lorenzo Moja ◽

Grazia Daniela Femminella ◽

...

Keyword(s):

Heart Failure ◽

Systematic Review ◽

Sinus Rhythm ◽

Oral Anticoagulation ◽

Meta Analysis ◽

Anticoagulation Therapy ◽

Oral Anticoagulation Therapy ◽

Heart Failure Patients

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Faculty Opinions recommendation of Oral anticoagulation therapy in heart failure patients in sinus rhythm: a systematic review and meta-analysis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717976292.793472365 ◽

2013 ◽

Author(s):

Arvind Bhimaraj

Keyword(s):

Heart Failure ◽

Systematic Review ◽

Sinus Rhythm ◽

Oral Anticoagulation ◽

Meta Analysis ◽

Anticoagulation Therapy ◽

Oral Anticoagulation Therapy ◽

Heart Failure Patients

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Effectiveness of vocational interventions for gaining paid work for people living with mild to moderate mental health conditions: systematic review and meta-analysis

BMJ Open ◽

10.1136/bmjopen-2020-039699 ◽

2020 ◽

Vol 10 (10) ◽

pp. e039699

Author(s):

Joanna K Fadyl ◽

David Anstiss ◽

Kirk Reed ◽

Mariya Khoronzhevych ◽

William M M Levack

Keyword(s):

Mental Health ◽

Systematic Review ◽

Vocational Rehabilitation ◽

Usual Care ◽

Meta Analysis ◽

Health Conditions ◽

Competitive Employment ◽

Paid Work ◽

Mental Health Conditions ◽

Quality Evidence

ObjectivesTo evaluate the effectiveness of vocational interventions to help people living with mild to moderate mental health conditions gain paid work.MethodsSystematic review of international, peer-reviewed literature. Development of the prepublished protocol and search strategy was done in consultation with stakeholder reference groups consisting of people with lived experience of long-term conditions, advocates and clinicians. We searched academic databases MEDLINE, EMBASE, PsychINFO, AMED, CINAHL, Proquest Dissertations and Theses database, and Business Source Complete for controlled trials comparing a specific vocational intervention against a control intervention or usual care, published between 1 January 2004 and 1 August 2019. Two authors independently screened search results, extracted data and appraised studies using the Cochrane risk of bias tool.ResultsEleven studies met inclusion criteria. Seven studies investigated Individual Placement and Support (IPS) modified for people who were not in intensive mental health treatment services. These studies occurred settings such as community vocational rehabilitation services, a housing programme and community mental health services. The studies provided very low quality evidence that people who receive IPS-style vocational rehabilitation are more likely to gain competitive employment than people who receive usual care (risk ratio 1.70, 95% CI 1.23 to 2.34, seven studies, 1611 participants). The remaining four studies considered cognitive behavioural therapy or specific vocational rehabilitation interventions designed to fit a unique context. There was insufficient evidence from these studies to draw conclusions regarding the effectiveness of non-IPS forms of vocational rehabilitation for people with mild to moderate mental health conditions.DiscussionThe meta-analysis showed a clear intervention effect but low precision, and more high-quality studies are needed in this field. There is currently very low quality evidence that IPS-style intervention results in more participants in competitive employment compared with ‘usual care’ control groups in populations with mild to moderate mental health conditions.

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