M247 KWASHIORKOR AND ORAL AVERSION SECONDARY TO FOOD ALLERGY TESTING PERFORMED FOR ATOPIC DERMATITIS

2021 ◽  
Vol 127 (5) ◽  
pp. S118
Author(s):  
A. McIntyre ◽  
A. Singh
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Allergy Testing

Challenge of food allergy testing and avoidance in children with atopic dermatitis

2021 ◽  
Vol 14 (6) ◽  
pp. e243141
Author(s):  
Stephanie Ann Kubala ◽  
Paula Mariam Mohyi ◽  
Kristin Sokol ◽  
Pamela Frischmeyer-Guerrerio
Keyword(s):  
Primary Care ◽  
Atopic Dermatitis ◽  
Food Allergy ◽  
Growth Failure ◽  
Clinical History ◽  
Primary Care Providers ◽  
Care Providers ◽  
Immediate Hypersensitivity ◽  
Allergy Testing ◽  
Food Avoidance

Atopic dermatitis (AD) is a common presenting complaint by children and their caretakers to their primary care providers. On testing, children with AD frequently exhibit positive food-specific IgE levels in the absence of immediate allergic reactions. Misinterpretation of these false positive tests can lead to unnecessary food avoidance, which can have tremendous psychosocial, economic and nutritional consequences and, in some cases, facilitate the development of an immediate hypersensitivity to the food. We present a child with persistent AD who underwent broad testing that led to unnecessary food avoidance resulting in Vitamin D deficiency, growth failure and the development of an IgE-mediated food allergy. This case underscores the need for caution by primary care clinicians in using food avoidance diets as a treatment for AD and the importance of limiting allergy testing to foods only when the clinical history indicates an immediate hypersensitivity reaction.

scholarly journals A Combined Analysis of Gut and Skin Microbiota in Infants with Food Allergy and Atopic Dermatitis: A Pilot Study

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1682
Author(s):  
Ewa Łoś-Rycharska ◽  
Marcin Gołębiewski ◽  
Marcin Sikora ◽  
Tomasz Grzybowski ◽  
Marta Gorzkiewicz ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Gut Microbiota ◽  
Bacterial Species ◽  
Rrna Gene ◽  
Healthy Children ◽  
Skin Microbiota ◽  
Fecal Samples ◽  
Healthy Infants ◽  
Α Diversity

The gut microbiota in patients with food allergy, and the skin microbiota in atopic dermatitis patients differ from those of healthy people. We hypothesize that relationships may exist between gut and skin microbiota in patients with allergies. The aim of this study was to determine the possible relationship between gut and skin microbiota in patients with allergies, hence simultaneous analysis of the two compartments of microbiota was performed in infants with and without allergic symptoms. Fifty-nine infants with food allergy and/or atopic dermatitis and 28 healthy children were enrolled in the study. The skin and gut microbiota were evaluated using 16S rRNA gene amplicon sequencing. No significant differences in the α-diversity of dermal or fecal microbiota were observed between allergic and non-allergic infants; however, a significant relationship was found between bacterial community structure and allergy phenotypes, especially in the fecal samples. Certain clinical conditions were associated with characteristic bacterial taxa in the skin and gut microbiota. Positive correlations were found between skin and fecal samples in the abundance of Gemella among allergic infants, and Lactobacillus and Bacteroides among healthy infants. Although infants with allergies and healthy infants demonstrate microbiota with similar α-diversity, some differences in β-diversity and bacterial species abundance can be seen, which may depend on the phenotype of the allergy. For some organisms, their abundance in skin and feces samples may be correlated, and these correlations might serve as indicators of the host’s allergic state.

scholarly journals Food sensitization rate and immediate-type food allergy incidence among infantile atopic dermatitis

2018 ◽  
Vol 141 (2) ◽  
pp. AB162
Author(s):  
Yuki Ejiri ◽  
Tetsuharu Manabe ◽  
Noriyuki Yanagida ◽  
Sakura Sato ◽  
Motohiro Ebisawa
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Sensitization Rate ◽  
Food Sensitization

scholarly journals Mechanisms by Which Atopic Dermatitis Predisposes to Food Allergy and the Atopic March

2019 ◽  
Vol 11 (1) ◽  
pp. 4 ◽  
Author(s):  
Elizabeth Huiwen Tham ◽  
Donald Y.M. Leung
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Atopic March
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