scholarly journals Mechanisms by Which Atopic Dermatitis Predisposes to Food Allergy and the Atopic March

2019 ◽  
Vol 11 (1) ◽  
pp. 4 ◽  
Author(s):  
Elizabeth Huiwen Tham ◽  
Donald Y.M. Leung
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Atopic March

scholarly journals Skin Barrier Function and Its Importance at the Start of the Atopic March

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Mary Beth Hogan ◽  
Kathy Peele ◽  
Nevin W. Wilson
Keyword(s):  
Clinical Trials ◽  
Atopic Dermatitis ◽  
Food Allergy ◽  
Immune System ◽  
Barrier Function ◽  
Skin Barrier ◽  
Skin Barrier Function ◽  
Allergen Sensitization ◽  
Epidermal Barrier ◽  
Atopic March

Atopic dermatitis can be due to a variety of causes from nonatopic triggers to food allergy. Control of egress of water and protection from ingress of irritants and allergens are key components of cutaneous barrier function. Current research suggests that a degraded barrier function of the skin allows the immune system inappropriate access to environmental allergens. Epidermal aeroallergen exposure may allow sensitization to allergen possibly initiating the atopic march. Further research into connections between epidermal barrier function and possible allergen sensitization will be important to undertake. Future clinical trials focused on skin barrier protection may be of value as a possible intervention in prevention of the initiation of the atopic march.

Atopic Dermatitis, Food Allergy, and Anaphylaxis

Asthma ◽  
2014 ◽  
pp. 455-466
Author(s):  
Julie Wang ◽  
Hugh A. Sampson ◽  
Alessandro Fiocchi ◽  
Scott Sicherer
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Respiratory Symptoms ◽  
The Other ◽  
Food Allergies ◽  
Allergen Sensitization ◽  
Atopic March ◽  
Underlying Mechanisms ◽  
And Control ◽  
The Relationship

Asthma, food allergy, and atopic dermatitis are common disorders affecting children that often coexist. Children can develop atopic dermatitis in infancy and later develop food allergies as new foods are introduced. In these highly atopic children, respiratory symptoms can also develop. This pattern of allergic disease progression has been termed the “atopic march.” Allergic (TH2-biased) inflammation and allergen sensitization are underlying mechanisms of these disorders, and control of one disease may affect the outcomes of the other disorders. Therefore, an understanding of the relationship between these allergic entities is important.

scholarly journals A Combined Analysis of Gut and Skin Microbiota in Infants with Food Allergy and Atopic Dermatitis: A Pilot Study

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1682
Author(s):  
Ewa Łoś-Rycharska ◽  
Marcin Gołębiewski ◽  
Marcin Sikora ◽  
Tomasz Grzybowski ◽  
Marta Gorzkiewicz ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Gut Microbiota ◽  
Bacterial Species ◽  
Rrna Gene ◽  
Healthy Children ◽  
Skin Microbiota ◽  
Fecal Samples ◽  
Healthy Infants ◽  
Α Diversity

The gut microbiota in patients with food allergy, and the skin microbiota in atopic dermatitis patients differ from those of healthy people. We hypothesize that relationships may exist between gut and skin microbiota in patients with allergies. The aim of this study was to determine the possible relationship between gut and skin microbiota in patients with allergies, hence simultaneous analysis of the two compartments of microbiota was performed in infants with and without allergic symptoms. Fifty-nine infants with food allergy and/or atopic dermatitis and 28 healthy children were enrolled in the study. The skin and gut microbiota were evaluated using 16S rRNA gene amplicon sequencing. No significant differences in the α-diversity of dermal or fecal microbiota were observed between allergic and non-allergic infants; however, a significant relationship was found between bacterial community structure and allergy phenotypes, especially in the fecal samples. Certain clinical conditions were associated with characteristic bacterial taxa in the skin and gut microbiota. Positive correlations were found between skin and fecal samples in the abundance of Gemella among allergic infants, and Lactobacillus and Bacteroides among healthy infants. Although infants with allergies and healthy infants demonstrate microbiota with similar α-diversity, some differences in β-diversity and bacterial species abundance can be seen, which may depend on the phenotype of the allergy. For some organisms, their abundance in skin and feces samples may be correlated, and these correlations might serve as indicators of the host’s allergic state.

scholarly journals Food sensitization rate and immediate-type food allergy incidence among infantile atopic dermatitis

2018 ◽  
Vol 141 (2) ◽  
pp. AB162
Author(s):  
Yuki Ejiri ◽  
Tetsuharu Manabe ◽  
Noriyuki Yanagida ◽  
Sakura Sato ◽  
Motohiro Ebisawa
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Sensitization Rate ◽  
Food Sensitization

scholarly journals Rare occurrence of common filaggrin mutations in Turkish children with food allergy and atopic dermatitis

2020 ◽  
Vol 50 (8) ◽  
pp. 1865-1871
Author(s):  
Neşe VARDAR ACAR ◽  
Özlem CAVKAYTAR ◽  
Ebru ARIK YILMAZ ◽  
Betül BÜYÜKTİRYAKİ ◽  
Özge SOYER ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Food Allergy ◽  
Rare Occurrence ◽  
Turkish Children
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